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Article

Woolley, Michael J.; Simms, John; Uddin, Sifat; Poyner, David R. and Conner, Alex C. (2017). Relative antagonism of mutants of the CGRP receptor extracellular loop 2 domain (ECL2) using a truncated competitive antagonist (CGRP8-37):evidence for the dual involvement of ECL2 in the two-domain binding model. Biochemistry, 56 (30), pp. 3877-3880.

Routledge, Sarah J.; Ladds, Graham and Poyner, David R. (2017). The effects of RAMPs upon cell signalling. Molecular and Cellular Endocrinology, in pre ,

Wheatley, Mark; Charlton, Jack; Jamshad, Mohammed; Routledge, Sarah J.; Bailey, Sian; La-Borde, Penelope J.; Azam, Maria T.; Logan, Richard T.; Bill, Roslyn M.; Dafforn, Tim R. and Poyner, David R. (2016). GPCR-styrene maleic acid lipid particles (GPCR-SMALPs):their nature and potential. Biochemical Society Transactions, 44 (2), pp. 619-623.

Hay, Debbie L.; Walker, Christopher S.; Gingell, Joseph J.; Ladds, Graham; Reynolds, Christopher A. and Poyner, David R. (2016). Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins. Biochemical Society Transactions, 44 (2), pp. 568-573.

Jamshad, Mohammed; Charlton, Jack; Lin, Yu-Pin; Routledge, Sarah J; Bawa, Zharain; Knowles, Timothy J.; Overduin, Michael; Dekker, Niek; Dafforn, Tim R.; Bill, Roslyn M.; Poyner, David R. and Wheatley, Mark (2015). G-protein-coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent. Bioscience Reports, 35 (2),

Bawa, Zharain; Routledge, Sarah J.; Jamshad, Mohammed; Clare, Michelle; Sarkar, Debasmita; Dickerson, Ian; Ganzlin, Markus; Poyner, David R. and Bill, Roslyn M. (2014). Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. Microbial Cell Factories, 13 (1),

Hay, Debbie L.; Harris, Paul W.R.; Kowalczyk, Renata; Brimble, Margaret A.; Rathbone, Dan L; Barwell, James; Conner, Alex C. and Poyner, David R. (2014). Structure-activity relationships of the N-terminus of calcitonin gene-related peptide:key roles of alanine-5 and threonine-6 in receptor activation. British Journal of Pharmacology, 171 (2), pp. 415-426.

Woolley, Michael J.; Watkins, Harriet A.; Taddese, Bruck; Karakullukcu, Z. Gamze; Barwell, James; Smith, Kevin J.; Hay, Debbie L.; Poyner, David R.; Reynolds, Christopher A. and Conner, Alex C. (2013). The role of ECL2 in CGRP receptor activation:a combined modelling and experimental approach. Journal of the Royal Society Interface, 10 (88),

Vohra, Shabana; Taddese, Bruck; Conner, Alex C.; Poyner, David R.; Hay, Debbie L.; Barwell, James; Reeves, Philip J.; Upton, Graham J.G. and Reynolds, Christopher A. (2013). Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies. Journal of the Royal Society Interface, 10 (79),

Poyner, David R. and Hay, Debbie L. (2012). Secretin family (Class B) G protein-coupled receptors - from molecular to clinical perspectives. British Journal of Pharmacology, 166 (1), pp. 1-3.

Hong, Yanguo; Hay, Debbie L.; Quirion, Remi and Poyner, David R. (2012). The pharmacology of adrenomedullin 2/intermedin. British Journal of Pharmacology, 166 (1), pp. 110-120.

Barwell, James; Wootten, Denise; Simms, John; Hay, Debbie L. and Poyner, David R. (2012). RAMPs and CGRP receptors. Advances in Experimental Medicine and Biology, 744 , pp. 13-24.

Poyner, David R.; Hay, Debbie L. and Conner, Alex C. (2009). CGRP receptor antagonists:design and screening. Expert Opinion on Drug Discovery, 4 (12), pp. 1253-1265.

Hay, Debbie L. and Poyner, David R. (2009). Calcitonin gene-related peptide, adrenomedullin and flushing. Maturitas, 64 (2), pp. 104-108.

Bonander, Nicklas; Darby, Richard A.J.; Grgic, Ljuban; Bora, Nagamani; Wen, Jikai; Brogna, Saverio; Poyner, David R.; O'Neill, Michael A. A. and Bill, Roslyn M. (2009). Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield. Microbial Cell Factories, 8 (10),

Hay, Debbie L.; Poyner, David R. and Quirion, Remi (2008). International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor. Pharmacological Reviews, 60 (2), pp. 143-145.

Conner, Alex C.; Simms, John; Conner, Matthew T.; Wootten, Denise L.; Wheatley, Mark and Poyner, David R. (2006). Diverse functional motifs within the three intracellular loops of the CGRP1 receptor. Biochemistry, 45 (43), pp. 12976-12985.

Simms, John; Hay, Debbie L.; Wheatley, Mark and Poyner, David R. (2006). Characterization of the structure of RAMP1 by mutagenesis and molecular modeling. Biophysical Journal, 91 (2), pp. 662-669.

Takhshid, Mohammad A.; Poyner, David R.; Chabot, Jean-Guy; Fournier, Alain; Ma, Weiya; Zheng, Wen-Hua; Owji, Ali A. and Quirion, Remi (2006). Characterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene-related peptide (CGRP) receptors in dissociated rat spinal cord cell culture. British Journal of Pharmacology, 148 (4), pp. 459-468.

Conner, Alex C.; Simms, John; Howitt, Stephen G.; Wheatley, Mark and Poyner, David R. (2006). The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression. Journal of Biological Chemistry, 281 (3), pp. 1644-1651.

Hay, Debbie L.; Poyner, David R. and Sexton, Patrick M. (2006). GPCR modulation by RAMPs. Pharmacology and Therapeutics, 109 (1-2), pp. 173-197.

Hay, Debbie L.; Christopoulos, George; Christopoulos, Arthur; Poyner, David R. and Sexton, Patrick M. (2005). Pharmacological discrimination of calcitonin receptor:receptor activity-modifying protein complexes. Molecular Pharmacology, 67 (5), pp. 1655-1665.

Lattmann, Eric; Billington, David C.; Poyner, David R.; Arayarat, Pornthip; Howitt, Stephen B.; Lawrence, Spencer and Offel, Michael (2002). Combinatorial solid phase synthesis of multiply substituted 1,4-benzodiazepines and affinity studies on the CCK2 receptor (Part 1). Drug Design and Discovery, 18 (1), pp. 9-21.

Adams, Eric F.; Oikonomou, Eftychia; Bhamrah, Mandeep; Buchfelder, Michael; Mitchell, Rosalind and Poyner, David R. (2002). A polymorphism in the growth hormone-releasing hormone receptor gene: clinical significance? Regulatory peptides, 108 (2-3), pp. 125-128.

Hay, Debbie L.; Howitt, Stephen G.; Conner, Alex C.; Doods, Henri; Schindler, Marcus and Poyner, David R. (2002). A comparison of the actions of BIBN4096BS and CGRP 8-37 on CGRP and adrenomedullin receptors expressed on SK-N-MC, L6, Col 29 and Rat 2 cells. British Journal of Pharmacology, 137 (1), pp. 80-86.

Smith, David M.; Coppock, H.A.; Withers, D.J.; Owji, A.A.; Hay, D.L.; Choksi, T.P.; Chakravarty, P.; Legon, S. and Poyner, David R. (2002). Adrenomedullin: receptor and signal transduction. Biochemical Society Transactions, 30 (4), pp. 432-437.

Conner, Alex C.; Hay, Debbie L.; Howitt, S.G.; Kilk, K.; Langel, U.; Wheatley, Mark; Smith, David M. and Poyner, David R. (2002). Interaction of calcitonin-gene-related peptide with its receptors. Biochemical Society Transactions, 30 (4), pp. 451-455.

Choksi, Tejal; Hay, Debbie L.; Legon, Stephen; Poyner, David R.; Hagner, Stefanie; Bloom, Stephen R. and Smith, David M. (2002). Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines. British Journal of Pharmacology, 136 (5), pp. 784-792.

Lattmann, Eric; Sattayasai, Jintana; Billington, David C.; Poyner, David R.; Puapairoj, Prapawadee; Tiamkao, Siriporn; Airarat, Wanchai; Singh, Harjit; Offel, Michael and Poyner, David (2002). Synthesis and evaluation of N1-substituted-3-propyl-1,4-benzodiazepine-2-ones as cholecystokinin (CCK2) receptor ligands. Journal of Pharmacy and Pharmacology, 54 (6), pp. 827-834.

Brain, Susan. D.; Poyner, David R. and Hill, Raymond G. (2002). CGRP receptors:A headache to study, but will antagonists prove therapeutic in migraine? Trends in Pharmacological Sciences, 23 (2), pp. 51-53.

Conner, Alex C. and Poyner, David R. (2001). The perils of using the human genome sequence:Lessons from CALCRL. Trends in Pharmacological Sciences, 22 (6), p. 272.

Hirst, Peter H.; Riley, A.M.; Mills, S.J.; Spiers, Ian D.; Poyner, David R.; Freeman, Sally; Potter, B.V. and Smith, Anthony W. (1999). Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa. Journal of Applied Microbiology, 86 (3), pp. 537-543.

Poyner, David R.; Taylor, Gillian M.; Tomlinson, A. Elaine; Richardson, Alan G. and Smith, David M. (1999). Characterization of receptors for calcitonin gene-related peptide and adrenomedullin on the guinea-pig vas deferens. British Journal of Pharmacology, 126 (5), pp. 1276-1282.

Poyner, David R.; Soomets, Ursel; Howitt, Stephen G. and Langel, Ulo (1998). Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells:Studies with chimeric and other peptides. British Journal of Pharmacology, 124 (8), pp. 1659-1666.

Poyner, David R. (1997). Molecular pharmacology of receptors for calcitonin-gene-related peptide, amylin and adrenomedullin. Biochemical Society Transactions, 25 (3), pp. 1032-1036.

Gosling, Martin; Akhtar, Saghir; Smith, J.W. and Poyner, David R. (1996). Direct inhibitory effects of an antisense oligodeoxynucleotide upon the volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Biochemical and Biophysical Research Communications, 227 (1), pp. 15-19.

Gosling, Martin; Smith, J.W. and Poyner, David R. (1995). Activation of calcium-sensitive potassium channels in L6 skeletal myocytes by arginine vasopressin requires extracellular calcium. Biochemical and Biophysical Research Communications, 217 (3), pp. 1163-1168.

Denny, Brian J.; Lambert, Peter A. and Poyner, David R. (1995). Molecular modelling of the human formyl peptide receptor. Biochemical Society Transactions, 23 (1), 96S.

Gosling, Martin; Smith, John W. and Poyner, David R. (1994). Regulation of membrane potential by G-protein-coupled receptors in L6 skeletal myocytes: the role of second messengers. Biochemical Society Transactions, 21 (4), 433S.

Gosling, Martin; Poyner, David R. and Smith, John W. (1993). Stimulation of chloride secretion and adenylate cyclase secretion in human colonic derived cell lines by calcitonin gene-related peptide. Biochemical Society Transactions, 21 (4), 434S.

Stanley, Alison F.; Hawkins, Phillip T.; Poyner, David R. and Hanley, Michael R. (1992). Metabolism of myo-inositol pentakisphosphates in mammalian brain. Biochemical Society Transactions, 20 (2), 149S.

Poyner, David R.; Jackson, Trevor R. and Hawkins, Phillip T. (1992). Stimulation of phosphatidylinositol-3-kinase by insulin-like growth factor 1 and other agonists. Biochemical Society Transactions, 20 (2), 140S.

Hanley, Michael R.; Poyner, David R. and Hawkins, Phillip T. (1991). Inositol phospholipids and phosphates for investigation of intact cell phospholipase C substrates and products. Methods in Enzymology, 197 , pp. 149-158.

Poyner, David R.; Hawkins, Phillip T.; Benton, H.P. and Hanley, Michael R. (1990). Changes in inositol lipids and phosphates after stimulation of the MAS-transfected NG115-401L-C3 cell line by mitogenic and non-mitogenic stimuli. Biochemical Journal, 271 (3), pp. 605-611.

Routledge, Sarah J.; Poyner, David R. and Bill, Roslyn M. Antifoams:the overlooked additive? Pharmaceutical Bioprocessing, 2 (2), pp. 103-106.

Poyner, David R.; Birdsall, N.J.; Curtis, C.; Eveleigh, P.; Hulme, E.C.; Pedder, E.K. and Wheatley, Mark Binding and hydrodynamic properties of muscarinic receptor subtypes solubilized in 3-(3-cholamidopropyl)dimethylammonio-2-hydroxy-1-propanesulfonate. Molecular Pharmacology, 36 (3), pp. 420-429.

Hay, Debbie L.; Howitt, Stephen G.; Conner, Alex C.; Schindler, Marcus; Smith, David M. and Poyner, David R. CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors:a comparison of effects of adrenomedullin 22-52, CGRP 8-37 and BIBN4096BS. British Journal of Pharmacology, 140 (3), pp. 477-486.

Barwell, James; Gingell, Joseph J.; Watkins, Harriet A.; Archbold, Julia K.; Poyner, David R. and Hay, Debbie L. Calcitonin and calcitonin receptor-like receptors:common themes with family B GPCRs? British Journal of Pharmacology, 166 (1), pp. 51-65.

Poyner, David R. Calcitonin gene-related peptide:multiple actions, multiple receptors. Pharmacology and Therapeutics, 56 (1), pp. 23-51.

Gosling, Martin; Smith, J.W. and Poyner, David R. Characterization of a volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Journal of Physiology, 485 (3), pp. 671-682.

Poyner, David R.; Cooke, F.; Hanley, Michael R.; Reynolds, D.J. and Hawkins, Phillip T. Characterization of metal ion-induced [3H]inositol hexakisphosphate binding to rat cerebellar membranes. Journal of Biological Chemistry, 268 (2), pp. 1032-1038.

Hay, Debbie L.; Poyner, David R. and Smith, David M. Desensitisation of adrenomedullin and CGRP receptors. Regulatory peptides, 112 (1-3), pp. 139-145.

Chugunov, Anton O.; Simms, John; Poyner, David R.; Dehouck, Yves; Rooman, Marianne; Gilis, Dimitri and Langer, Ingrid Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation. Molecular Pharmacology, 78 (3), pp. 394-401.

Poyner, David R. and Wheatley, M. Family resemblances? Ligand binding and activation of family A and B G-protein-coupled receptors. Biochemical Society Transactions, 35 (4), pp. 707-708.

Conner, Matthew; Hicks, Matthew R.; Dafforn, Tim; Knowles, Timothy J.; Ludwig, Christian; Staddon, Susan; Overduin, Michael; Günther, Ulrich L.; Thome, Johannes; Wheatley, M.; Poyner, David R. and Conner, Alex C. Functional and biophysical analysis of the C-terminus of the CGRP-receptor; a family B GPCR. Biochemistry, 47 (32), pp. 8434-8444.

Chini, Bice; Parenti, Marco; Poyner, David R. and Wheatley, Mark G-protein-coupled receptors:from structural insights to functional mechanisms. Biochemical Society Transactions, 41 (1), 135–136.

Hawkins, Phillip T.; Reynolds, D.J.M.; Poyner, David R. and Hanley, Michael R. Identification of a novel inositol phosphate recognition site: specific [3H]inositol hexakisphosphate binding to brain regions and cerebellar membranes. Biochemical and Biophysical Research Communications, 167 (2), pp. 819-827.

Hawkins, Phillip T.; Poyner, David R.; Jackson, T.R.; Letcher, A.J.; Lander, Dawn and Irvine, R.F. Inhibition of iron-catalysed hydroxyl radical formation by inositol polyphosphates: a possible physiological function for myo-inositol hexakisphosphate. Biochemical Journal, 294 , pp. 929-934.

Poyner, David R.; Sexton, Patrick M.; Marshall, Ian; Smith, David M.; Quirion, Remi; Born, Walter; Muff, Roman; Fischer, Jan A. and Foord, Steven M. International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacological Reviews, 54 (2), pp. 233-246.

Wheatley, M.; Wootten, Denise; Conner, Matthew T.; Simms, John; Kendrick, R.; Logan, R.T.; Poyner, David R. and Barwell, James Lifting the lid on GPCRs:the role of extracellular loops. British Journal of Pharmacology, 165 (6), pp. 1688-1703.

Barwell, James; Miller, Philip S.; Donnelly, Dan and Poyner, David R. Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor. Peptides, 31 (1), pp. 170-176.

Sexton, Patrick M.; Poyner, David R.; Simms, John; Christopoulos, Arthur and Hay, Debbie L. Modulating receptor function through RAMPs:can they represent drug targets in themselves? Drug Discovery Today, 14 (7-8), pp. 413-419.

Miller, Philip S.; Barwell, James; Poyner, David R.; Wigglesworth, Mark J.; Garland, Stephen L. and Donnelly, Dan Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74. Biochemical and Biophysical Research Communications, 391 (1), pp. 437-442.

Sexton, Patrick M.; Poyner, David R.; Simms, John; Christopoulos, Arthur and Hay, Debbie L. RAMPs as drug targets. Advances in Experimental Medicine and Biology, 744 , pp. 61-74.

Woolley, Michael J.; Reynolds, Christopher A.; Simms, John; Walker, Christopher S.; Mobarec, Juan Carlos; Garelja, Michael L.; Conner, Alex C.; Poyner, David R. and Hay, Debbie L. Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs. Biochemical Pharmacology, in pre ,

Weston, Cathryn; Winfield, Ian; Harris, Matthew; Hodgson, Rose; Shah, Archna; Dowell, Simon J.; Mobarec, Juan Carlos; Woodlock, David A.; Reynolds, Christopher A.; Poyner, David R.; Watkins, Harriet A. and Ladds, Graham Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors. Journal of Biological Chemistry, 291 (42), pp. 21925-21944.

Watkins, Harriet A.; Chakravarthy, Madhuri; Abhayawardana, Rekhati S.; Gingell, Joseph J.; Garelja, Michael; Pardamwar, Meenakshi; McElhinney, James M.W.R.; Lathbridge, Alex; Constantine, Arran; Harris, Paul W.R.; Yuen, Tsz-Ying; Brimble, Margaret A.; Barwell, James; Poyner, David R.; Woolley, Michael J.; Conner, Alex C.; Pioszak, Augen A.; Reynolds, Christopher A. and Hay, Debbie L. Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties. Journal of Biological Chemistry, 291 (22), pp. 11657-11675.

Poyner, David R.; Hanley, Michael R.; Jackson, T.R. and Hawkins, Phillip T. Receptor regulation of phosphoinositide 3-hydroxykinase in the NG115-401L-C3 neuronal cell line: stimulation by insulin-like growth factor-I. Biochemical Journal, 290 , pp. 901-905.

Smith, Anthony W.; Poyner, David R.; Hughes, H.K. and Lambert, Peter A. Siderophore activity of myo-inositol hexakisphosphate in Pseudomonas aeruginosa. Journal of Bacteriology, 176 (12), pp. 3455-3459.

D'Santos, C.S.; Gatti, A.; Poyner, David R. and Hanley, Michael R. Stimulation of adenylate cyclase by amylin in CHO-K1 cells. Molecular Pharmacology, 41 (5), pp. 894-899.

Booe, Jason M.; Walker, Christopher S.; Barwell, James; Kuteyi, Gabriel; Simms, John; Jamaluddin, Muhammad A.; Warner, Margaret L.; Bill, Roslyn M.; Harris, Paul W.; Brimble, Margaret A.; Poyner, David R.; Hay, Debbie L. and Pioszak, Augen A. Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor. Molecular Cell, 58 (6), pp. 1040-1052.

Simms, John; Hay, Debbie L.; Bailey, Richard J.; Konycheva, Galina; Bailey, Graham; Wheatley, Mark and Poyner, David R. Structure-function analysis of RAMP1 by Alanine Mutagenesis. Biochemistry, 48 (1), pp. 198-205.

Qi, Tao; Ly, Kien; Poyner, David R.; Christopoulos, George; Sexton, Patrick M. and Hay, Debbie L. Structure-function analysis of amino acid 74 of human RAMP1 and RAMP3 and its role in peptide interactions with adrenomedullin and calcitonin gene-related peptide receptors. Peptides, 32 (5), pp. 1060-1067.

Jamshad, Mohammed; Lin, Yu-Pin; Knowles, Timothy J.; Parslow, Rosemary A.; Harris, Craig; Wheatley, Mark; Poyner, David R.; Bill, Roslyn M.; Thomas, Owen R.T.; Overduin, Michael and Dafforn, Tim R. Surfactant-free purification of membrane proteins with intact native membrane environment. Biochemical Society Transactions, 39 (3), pp. 813-818.

Spiers, Ian D.; Barker, Christopher J.; Chung, Sung-Kee; Chang, Young-Tae; Freeman, Sally; Gardiner, John M.; Hirst, Peter H.; Lambert, Peter A.; Michell, Robert H.; Poyner, David R.; Schwalbe, Carl H.; Smith, Anthony W. and Solomons, Kevin R. H. Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (+/-)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates. Carbohydrate Research, 282 (1), pp. 81-99.

Woolley, Michael J.; Simms, John; Mobarec, Juan Carlos; Reynolds, Christopher A.; Poyner, David R. and Conner, Alex C. Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach. Molecular and Cellular Endocrinology, in pre ,

Barwell, James; Wheatley, Mark; Conner, Alex C.; Taddese, Bruck; Vohra, Shabana; Reynolds, Christopher A. and Poyner, David R. The activation of the CGRP receptor. Biochemical Society Transactions, 41 (1), pp. 180-184.

Gingell, Joseph J.; Simms, John; Barwell, James; Poyner, David R.; Watkins, Harriet A.; Pioszak, Augen A.; Sexton, Patrick M. and Hay, Debbie L. An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology. Cell Discovery, 2 ,

Conner, Alex C.; Hay, Debbie L.; Simms, John; Howitt, Stephen G.; Schindler, Marcus; Smith, David M.; Wheatley, Mark and Poyner, David R. A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling:implications for family B G-protein-coupled receptors. Molecular Pharmacology, 67 (1), pp. 20-31.

Stephens, L.R.; Hawkins, Phillip T.; Stanley, Alison F.; Moore, T.; Poyner, David R.; Morris, P.J.; Hanley, Michael R.; Kay, R.R. and Irvine, R.F. myo-inositol pentakisphosphates. Structure, biological occurrence and phosphorylation to myo-inositol hexakisphosphate. Biochemical Journal, 275 , pp. 485-499.

Adams, Eric F.; Symowski, Hedwig; Buchfelder, Michael and Poyner, David R. A polymorphism in the growth hormone (GH)-releasing hormone (GHRH) receptor gene is associated with elevated response to GHRH by human pituitary somatotrophinomas in vitro. Biochemical and Biophysical Research Communications, 275 (1), pp. 33-36.

Howitt, Stephen G.; Kilk, Kalle; Wang, Yang; Smith, David M.; Langel, Ulo and Poyner, David R. The role of the 8-18 helix of CGRP 8-37 in mediating high affinity binding to CGRP receptors; coulombic and steric interactions. British Journal of Pharmacology, 138 (2), pp. 325-332.

Book Section

Poyner, David R. and Wheatley, Mark (2010). Preface. IN: G protein-coupled receptors. Poyner, David R. and Wheatley, Mark (eds) Wiley-Blackwell.

Poyner, David R. (2008). RAMPs and the modulation of G-protein coupled receptors. IN: Proceeedings of the XXVIII European Section Meeting of the International Society gor Heart Research. Bologna (IT): Monduzzi.

Conner, Alex C.; Hay, Debbie L. and Poyner, David R. (2005). Characterization of CGRP receptor binding. IN: Current protocols in pharmacology. Wiley.

Conner, Alex C.; Barwell, James; Poyner, David R. and Wheatley, Mark The use of site-directed mutagenesis to study GPCRs. IN: Receptor signal transduction protocols. Willars, Gary B. and Challiss, R.A. John (eds) Methods in molecular biology (3rd ed). Humana Press.

This list was generated on Tue Apr 10 01:07:39 2018 BST.