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Grove, Joe; Hu, Ke; Farquhar, Michelle J.; Goodall, Margaret; Walker, Lucas; Jamshad, Mohammed; Drummer, Heidi E.; Bill, Roslyn M.; Balfe, Peter and McKeating, Jane A. (2017). A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81. Wellcome Open Research, 2 , p. 82.

Salman, Mootaz M.; Sheilabi, Mariam A.; Bhattacharyya, Dev; Kitchen, Philip; Conner, Alex C.; Bill, Roslyn M.; Woodroofe, M. Nicola; Conner, Matthew T. and Princivalle, Alessandra P. (2017). Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy. European Journal of Neuroscience, 46 (5), pp. 2121-2132.

Tran, Anh-Minh; Nguyen, Thanh-Thao; Nguyen, Cong-Thuan; Huynh-Thi, Xuan-Mai; Nguyen, Cao-Tri; Trinh, Minh-Thuong; Tran, Linh-Thuoc; Cartwright, Stephanie P.; Bill, Roslyn M. and Tran-Van, Hieu (2017). Pichia pastoris versus Saccharomyces cerevisiae:a case study on the recombinant production of human granulocyte-macrophage colony-stimulating factor. BMC Research Notes, 10 (1),

Hardy, David; Bill, Roslyn M.; Jawhari, Anass and Rothnie, Alice J. (2016). Overcoming bottlenecks in the membrane protein structural biology pipeline. Biochemical Society Transactions, 44 (3), pp. 838-844.

Wheatley, Mark; Charlton, Jack; Jamshad, Mohammed; Routledge, Sarah J.; Bailey, Sian; La-Borde, Penelope J.; Azam, Maria T.; Logan, Richard T.; Bill, Roslyn M.; Dafforn, Tim R. and Poyner, David R. (2016). GPCR-styrene maleic acid lipid particles (GPCR-SMALPs):their nature and potential. Biochemical Society Transactions, 44 (2), pp. 619-623.

Kitchen, Philip; Conner, Matthew T.; Bill, Roslyn M. and Conner, Alex C. (2016). Structural determinants of oligomerization of the aquaporin-4 channel. Journal of Biological Chemistry, 291 (13), pp. 6858-6871.

Kitchen, Philip; Öberg, Fredrik; Sjöhamn, Jennie; Hedfalk, Kristina; Bill, Roslyn M.; Conner, Alex C.; Conner, Matthew T. and Törnroth-Horsefield, Susanna (2015). Plasma membrane abundance of human aquaporin 5 is dynamically regulated by multiple pathways. PLoS ONE, 10 (11),

Kitchen, Philip; Day, Rebecca E.; Taylor, Luke H.J.; Salman, Mootaz M.; Bill, Roslyn M.; Conner, Matthew T. and Conner, Alex C. (2015). Identification and molecular mechanisms of the rapid tonicity-induced relocalization of the aquaporin 4 channel. Journal of Biological Chemistry, 290 , pp. 16873-16881.

Jamshad, Mohammed; Charlton, Jack; Lin, Yu-Pin; Routledge, Sarah J; Bawa, Zharain; Knowles, Timothy J.; Overduin, Michael; Dekker, Niek; Dafforn, Tim R.; Bill, Roslyn M.; Poyner, David R. and Wheatley, Mark (2015). G-protein-coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent. Bioscience Reports, 35 (2),

Bill, Roslyn M. (2015). Recombinant protein subunit vaccine synthesis in microbes:a role for yeast? Journal of Pharmacy and Pharmacology, 67 (3), pp. 319-328.

Bawa, Zharain; Routledge, Sarah J.; Jamshad, Mohammed; Clare, Michelle; Sarkar, Debasmita; Dickerson, Ian; Ganzlin, Markus; Poyner, David R. and Bill, Roslyn M. (2014). Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. Microbial Cell Factories, 13 (1),

Day, Rebecca E.; Kitchen, Philip; Owen, David; Bland, Charlotte; Marshall, Lindsay; Conner, Alex C.; Bill, Roslyn M. and Conner, Matthew T. (2014). Human aquaporins:regulators of transcellular water flow. BBA - General Subjects ,

Bill, Roslyn M. (2014). Playing catch-up with Escherichia coli:using yeast to increase success rates in recombinant protein production experiments. Frontiers in Microbiology, 5 ,

Bonander, Nicklas; Jamshad, Mohammed; Oberthür, Dominik; Clare, Michelle; Barwell, James; Hu, Ke; Farquhar, Michelle J.; Stamataki, Zania; Harris, Helen J.; Dierks, Karsten; Dafforn, Timothy R.; Betzel, Christian; McKeating, Jane A. and Bill, Roslyn M. (2013). Production, purification and characterization of recombinant, full-length human claudin-1. PLoS ONE, 8 (5),

Bill, Roslyn M. and Byrne, Bernadette (2013). Foreword for EDICT Special Edition, volume 2. Molecular Membrane Biology, 30 (2), p. 113.

Bonander, Nicklas and Bill, Roslyn M. (2012). Optimising yeast as a host for recombinant protein production (review). Methods in molecular biology, 866 , pp. 1-9.

Bora, Nagamani; Bawa, Zharain; Bill, Roslyn M. and Wilks, Martin D.B. (2012). The implementation of a design of experiments strategy to increase recombinant protein yields in yeast (review). Methods in molecular biology, 866 , pp. 115-127.

Kitson, Susan M.; Mullen, William; Cogdell, Richard J.; Bill, Roslyn M. and Fraser, Niall J. (2011). GPCR production in a novel yeast strain that makes cholesterol-like sterols. Methods, 55 (4), pp. 287-292.

Ferndahl, Cecilia; Bonander, Nicklas; Logez, Christel; Wagner, Renaud; Gustafsson, Lena; Larsson, Christer; Hedfalk, Kristina; Darby, Richard A.J. and Bill, Roslyn M. (2010). Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield:the use of a respiratory strain as a microbial cell factory. Microbial Cell Factories, 9 , p. 47.

Holmes, William J.; Darby, Richard A.J.; Wilks, Martin D.B.; Smith, Rodney and Bill, Roslyn M. (2009). Developing a scalable model of recombinant protein yield from Pichia pastoris:the influence of culture conditions, biomass and induction regime. Microbial Cell Factories, 8 (35), p. 35.

Bonander, Nicklas; Darby, Richard A.J.; Grgic, Ljuban; Bora, Nagamani; Wen, Jikai; Brogna, Saverio; Poyner, David R.; O'Neill, Michael A. A. and Bill, Roslyn M. (2009). Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield. Microbial Cell Factories, 8 (10),

Jamshad, Mohammed; Rajesh, Sundaresan; Stamataki, Zania; McKeating, Jane A; Dafforn, Timothy; Overduin, Michael and Bill, Roslyn M. (2008). Structural characterization of recombinant human CD81 produced in Pichia pastoris. Protein Expression and Purification, 57 (2), pp. 206-216.

Saidijam, M.; Bettaney, K.E.; Szakonyi, G.; Psakis, G.; Shibayama, K.; Suzuki, S.; Clough, J.L.; Blessie, V.; Abu-bakr, A.; Baumberg, S.; Meuller, J.; Hoyle, C.K.; Palmer, S.L.; Butaye, P.; Walravens, K.; Patching, S.G.; O'Reilly, J.; Rutherford, NG.; Bill, Roslyn M.; Roper, D.I.; Phillips-Jones, M.K. and Henderson, P.J.F. (2005). Active membrane transport and receptor proteins from bacteria. Biochemical Society Transactions, 33 (Part 4), pp. 867-872.

Karlgren, Sara; Pettersson, Nina; Nordlander, Bodil; Mathai, John C.; Brodsky, Jeffrey L.; Zeidel, Mark L.; Bill, Roslyn M. and Hohmann, Stefan (2005). Conditional osmotic stress in yeast:a system to study transport through aquaglyceroporins and osmostress signaling. Journal of Biological Chemistry, 280 (8), pp. 7186-7193.

Althage, Magnus; Karlsson, Jenny; Gourdon, Pontus; Levin, Mikael; Bill, Roslyn M.; Tigerström, Anna and Rydström, Jan (2003). Functional split and crosslinking of the membrane domain of the β subunit of proton-translocating transhydrogenase from Escherichia coli. Biochemistry, 42 (37), pp. 10998-11003.

Filipsson, C.; Hedfalk, K.; Rydström, Jan; Hohmann, Sara and Bill, Roslyn M. (2003). Analysis of the control of the Fps1p glycerol efflux channel. Yeast, 20 (Suppl.), S247.

Bill, Roslyn M.; Hedfalk, Kristina; Karlgren, Sara; Mullins, Jonathan G.L.; Rydström, Jan and Hohmann, Stefan (2001). Analysis of the pore of the unusual major intrinsic protein channel, yeast Fps1p. Journal of Biological Chemistry, 276 (39), pp. 36543-36549.

Macmillan, Derek; Bill, Roslyn M.; Sage, Karen A.; Fern, Dominic and Flitsch, Sabine L. (2001). Selective in vitro glycosylation of recombinant proteins:semi-synthesis of novel homogeneous glycoforms of human erythropoietin. Chemistry and Biology, 8 (2), pp. 133-145.

Karlgren, Sara; Bill, Roslyn M. and Hohmann, Stefan (2001). Polyol transport in yeast: studying transport proteins and manipulating osmotic responses. Yeast, 18 (Suppl.), S266.

Routledge, Sarah J.; Hewitt, Christopher J.; Bora, Nagamani and Bill, Roslyn M. Antifoam addition to shake flask cultures of recombinant Pichia pastoris increases yield. Microbial Cell Factories, 10 (17),

Routledge, Sarah J.; Poyner, David R. and Bill, Roslyn M. Antifoams:the overlooked additive? Pharmaceutical Bioprocessing, 2 (2), pp. 103-106.

Chan, K. L. Andrew; Govada, Lata; Bill, Roslyn M.; Chayen, Naomi E. and Kazarian, Sergei G. Attenuated total reflection-FT-IR spectroscopic imaging of protein crystallization. Analytical Chemistry, 81 (10), pp. 3769-3775.

Kitchen, Philip; Day, Rebecca E.; Salman, Mootaz M.; Conner, Matthew T.; Bill, Roslyn M. and Conner, Alex C. Beyond water homeostasis:diverse functional roles of mammalian aquaporins. BBA - General Subjects, 1850 (12), pp. 2410-2421.

Hipkiss, Alan R.; Cartwright, Stephanie P.; Bromley, Clare; Gross, Stephane R. and Bill, Roslyn M. Carnosine:can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential? Chemistry Central Journal, 7 (1),

Cartwright, Stephanie P.; Darby, Richard A.J.; Sarkar, Debasmita; Bonander, Nicklas; Gross, Stephane R.; Ashe, Mark P. and Bill, Roslyn M. Constitutively-stressed yeast strains are high-yielding for recombinant Fps1:implications for the translational regulation of an aquaporin. Microbial Cell Factories, 16 (1),

Bonander, Nicklas; Hedfalk, Kristina; Larsson, Christer; Mostad, Petter; Chang, Celia; Gustafsson, Lena and Bill, Roslyn M. Design of improved membrane protein production experiments:quantitation of the host response. Protein Science, 14 (7), pp. 1729-1740.

Berger, Imre and Bill, Roslyn M. Editorial overview:new protein production tools for structural biology. Current Opinion in Structural Biology, 32 , v–vii.

Aricescu, A.R.; Assenberg, R.; Bill, Roslyn M.; Busso, D.; Chang, V.T.; Davis, S.J.; Dubrovsky, A.; Gustafsson, L.; Hedfalk, K.; Heinemann, U.; Jones, I.M.; Ksiazek, D.; Lang, C.; Maskos, K.; Messerschmidt, A.; Macieira, S.; Peleg, Y.; Perrakis, A.; Poterszman, A.; Schneider, G.; Sixma, T.K.; Sussman, J.L.; Sutton, G.; Tarboureich, N.; Zeev-Ben-Mordehai, T. and Jones, E. Yvonne Eukaryotic expression:Developments for structural proteomics. Acta Crystallographica: Section D, 62 (10), pp. 1114-1124.

Nyblom, Maria; Öberg, Fredrik; Lindkvist-Petersson, Karin; Hallgren, Karin; Findlay, Heather; Wikström, Jennie; Karlsson, Anders; Hansson, Örjan; Booth, Paula J; Bill, Roslyn M.; Neutze, Richard and Hedfalk, Kristina Exceptional overproduction of a functional human membrane protein. Protein Expression and Purification, 56 (1), pp. 110-120.

Pettersson, Nina; Hagström, Johan; Bill, Roslyn M. and Hohmann, Stefan Expression of heterologous aquaporins for functional analysis in Saccharomyces cerevisiae. Current Genetics, 50 (4), pp. 247-255.

Bill, Roslyn M. and von der Haar, Tobias Hijacked then lost in translation:the plight of the recombinant host cell in membrane protein structural biology projects. Current Opinion in Structural Biology, 32 , pp. 147-155.

Karlgren, Sara; Filipsson, Caroline; Mullins, Jonathan G.L.; Bill, Roslyn M.; Tamás, Markus J. and Hohmann, Stefan Identification of residues controlling transport through the yeast aquaglyceroporin Fps1 using a genetic screen. FEBS journal, 271 (4), pp. 771-779.

Fantoni, Adele; Bill, Roslyn M.; Gustafsson, Lena and Hedfalk, Kristina Improved yields of full-length functional human FGF1 can be achieved using the methylotrophic yeast Pichia pastoris. Protein Expression and Purification, 52 (1), pp. 31-39.

Öberg, Fredrik; Sjöhamn, Jennie; Conner, Matthew T.; Bill, Roslyn M. and Hedfalk, Kristina Improving recombinant eukaryotic membrane protein yields in Pichia pastoris:the importance of codon optimization and clone selection. Molecular Membrane Biology, 28 (6), pp. 398-411.

Bill, Roslyn M. and Byrne, Bernadette Introduction to EDICT volume 1. Molecular Membrane Biology, 30 (1), p. 2.

Cartwright, Stephanie P.; Bill, Roslyn M. and Hipkiss, Alan R. L-carnosine affects the growth of Saccharomyces cerevisiae in a metabolism-dependent manner. PLoS ONE, 7 (9),

Conner, Matthew T.; Conner, Alex C.; Brown, James and Bill, Roslyn M. Membrane trafficking of aquaporin 1 is mediated by protein kinase C via microtubules and regulated by tonicity. Biochemistry, 49 (5), pp. 821-823.

Bill, Roslyn M.; Henderson, Peter J.F.; Iwata, So; Kunji, Edmund R.S.; Michel, Hartmut; Neutze, Richard; Newstead, Simon; Poolman, Bert; Tate, Christopher G. and Vogel, Horst Overcoming barriers to membrane protein structure determination. Nature Biotechnology, 29 (4), pp. 335-340.

Jamshad, Mohammed; Darby, Richard A. J.; Grgic, Ljuban and Bill, Roslyn M. Production of membrane proteins in yeast. Biochemistry and Cell Biology, 84 (6), p. 1069.

Conner, Matthew T.; Conner, Alex C.; Bland, Charlotte E.; Taylor, Luke H.J.; Brown, James; Parri, H. Rheinallt and Bill, Roslyn M. Rapid aquaporin translocation regulates cellular water flow:the mechanism of hypotonicity-induced sub-cellular localization of the aquaporin 1 water channel. Journal of Biological Chemistry, 287 (14), pp. 11516-11525.

Cartwright, Stephanie; Bill, Roslyn M.; Bui, Sy Tien; Van, Hieu Tran and Nguyen, Hung Minh Rapid expression and purification of the hepatitis delta virus antigen using the methylotropic yeast Pichia pastoris. BMC Research Notes, 10 ,

Bonander, Nicklas and Bill, Roslyn M. Relieving the first bottleneck in the drug discovery pipeline:using array technologies to rationalize membrane protein production. Expert Review of Proteomics, 6 (5), pp. 501-505.

Elbing, Karin; Larsson, Christer; Bill, Roslyn M.; Albers, Eva; Snoep, Jacky L.; Boles, Eckhard; Hohmann, Stefan and Gustafsson, Lena Role of hexose transport in control of glycolytic flux in Saccharomyces cerevisiae. Applied and Environmental Microbiology, 70 (9), pp. 5323-5330.

Booe, Jason M.; Walker, Christopher S.; Barwell, James; Kuteyi, Gabriel; Simms, John; Jamaluddin, Muhammad A.; Warner, Margaret L.; Bill, Roslyn M.; Harris, Paul W.; Brimble, Margaret A.; Poyner, David R.; Hay, Debbie L. and Pioszak, Augen A. Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor. Molecular Cell, 58 (6), pp. 1040-1052.

Jamshad, Mohammed; Lin, Yu-Pin; Knowles, Timothy J.; Parslow, Rosemary A.; Harris, Craig; Wheatley, Mark; Poyner, David R.; Bill, Roslyn M.; Thomas, Owen R.T.; Overduin, Michael and Dafforn, Tim R. Surfactant-free purification of membrane proteins with intact native membrane environment. Biochemical Society Transactions, 39 (3), pp. 813-818.

Otterstedt, Karin; Larsson, Christer; Bill, Roslyn M.; Ståhlberg, Anders; Boles, Eckhard; Hohmann, Stefan and Gustafsson, Lena Switching the mode of metabolism in the yeast Saccharomyces cerevisiae. Embo Reports, 5 (5), pp. 532-537.

Bonander, Nicklas; Ferndahl, Cecilia; Mostad, Petter; Wilks, Martin D.B.; Chang, Celia; Showe, Louise; Gustafsson, Lena; Larsson, Christer and Bill, Roslyn M. Transcriptome analysis of a respiratory Saccharomyces cerevisiae strain suggests the expression of its phenotype is glucose insensitive and predominantly controlled by Hap4, Cat8 and Mig1. BMC Genomics, 9 (365),

Bawa, Zharain; Bland, Charlotte E.; Bonander, Nicklas; Bora, Nagamani; Cartwright, Stephanie P.; Clare, Michelle; Conner, Matthew T.; Darby, Richard A.J.; Dilworth, Marvin V; Holmes, William J.; Jamshad, Mohammed; Routledge, Sarah J.; Gross, Stephane R. and Bill, Roslyn M. Understanding the yeast host cell response to recombinant membrane protein production. Biochemical Society Transactions, 39 (3), pp. 719-723.

Conner, Alex C.; Bill, Roslyn M. and Conner, Matthew T. An emerging consensus on aquaporin translocation as a regulatory mechanism. Molecular Membrane Biology, 30 (1), pp. 101-112.

Hedfalk, Kristina; Bill, Roslyn M.; Mullins, Jonathan G.L.; Karlgren, Sara; Filipsson, Caroline; Bergstrom, Johanna; Tamás, Markus J.; Rydström, Jan and Hohmann, Stefan A regulatory domain in the C-terminal extension of the yeast glycerol channel Fps1p. Journal of Biological Chemistry, 279 (15), pp. 14954-14960.

Tamás, Markus J.; Karlgren, Sara; Bill, Roslyn M.; Hedfalk, Kristina; Allegri, Laura; Ferreira, Marie; Thevelein, Johan M.; Rydström, Jan; Mullins, Jonathan G.L. and Hohmann, Stefan A short regulatory domain restricts glycerol transport through yeast Fps1p. Journal of Biological Chemistry, 278 (8), pp. 6337-6345.

Routledge, Sarah; Mikaliunaite, Lina; Patel, Anjana; Clare, Michelle; Cartwright, Stephanie P.; Bawa, Zharain; Wilks, Martin D.B.; Low, Floren; Hardy, David; Rothnie, Alice J. and Bill, Roslyn M. The synthesis of recombinant membrane proteins in yeast for structural studies. Methods, 95 , pp. 26-37.

Book Section

Bonander, Nicklas and Bill, Roslyn M. (2012). Optimising yeast as a host for recombinant protein production (review). IN: Recombinant protein production in yeast. Bill, Roslyn M. (ed.) Springer protocols . Humana Press.

Darby, Richard A.J.; Jamshad, Mohammed; Grgic, Ljuban; Holmes, William J. and Bill, Roslyn M. (2010). Production of recombinant G protein-coupled receptor in yeast for structural and functional analysis. IN: G protein-coupled receptors. Poyner, David R. and Wheatley, Mark (eds) Wiley-Blackwell.

Cartwright, Stephanie P.; Mikaliunaite, Lina and Bill, Roslyn M. Membrane protein production in the Yeast, S. cerevisiae. IN: Heterologous expression of membrane proteins. Mus-Veteau, Isabelle (ed.) Methods in Molecular Biology . New York (US): Springer.

Bill, Roslyn M. Preface. IN: Recombinant protein production in yeast. Bill, Roslyn M. (ed.) Springer protocols . Humana Press.

Darby, Richard A.J.; Cartwright, Stephanie P.; Dilworth, Marvin V. and Bill, Roslyn M. Which yeast species shall I choose? Saccharomyces cerevisiae versus Pichia pastoris (review). IN: Recombinant protein production in yeast. Bill, Roslyn M. (ed.) Springer protocols . Humana Press.

Routledge, Sarah J. and Bill, Roslyn M. The effect of antifoam addition on protein production yields. IN: Recombinant protein production in yeast. Bill, Roslyn M. (ed.) Springer protocols . Humana Press.

Bora, Nagamani; Bawa, Zharain; Bill, Roslyn M. and Wilks, Martin D.B. The implementation of a design of experiments strategy to increase recombinant protein yields in yeast (review). IN: Recombinant protein production in yeast. Bill, Roslyn M. (ed.) Springer protocols . Humana Press.