Items where Division is "College of Health & Life Sciences > School of Biosciences" and Year is 2019

Abir-Awan, Mohammed, Kitchen, Philip, Salman, Mootaz M., Conner, Matthew T., Conner, Alex C. and Bill, Roslyn M. (2019). Inhibitors of Mammalian Aquaporin Water Channels. International Journal of Molecular Sciences, 20 (7),

Afonso, Catarina B. and Spickett, Corinne M. (2019). Lipoproteins as targets and markers of lipoxidation. Redox Biology, 23 ,

Al-shaeli, S J, Ethaeb, A M and Brown, J E (2019). Anti-neoplastic effect of epigallocatechin gallate on breast cancer cells through glucose metabolism. Journal of Physics: Conference Series, 1234 (1),

Allsop, Thomas D.P., Neal, Ronald, Wang, Changle, Nagel, David A, Hine, Anna V., Culverhouse, Philip F., Ania-Castañón, Juan Diego, Webb, David J, Scarano, Simona and Minunni, Maria (2019). An ultra-sensitive aptasensor on optical fibre for the direct detection of Bisphenol A. Biosensors and Bioelectronics, 135 , pp. 102-110.

Ayinde, Oluseyi, Wang, Zhuo, Pinton, Giulia, Moro, Laura and Griffin, Martin (2019). Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition. Oncotarget, 10 (44), pp. 4556-4569.

Ayub, Hoor (2019). Membrane phospholipids as regulators of tetraspanin oligomerisation. PHD thesis, Aston University.

Bailey, Clifford J (2019). FDA guidance on cardiovascular risk of antidiabetic therapies: one decade later. Diabetes, Obesity and Metabolism, 21 (5), pp. 1079-1080.

Bailey, Clifford J (2019). Uric acid and the cardio-renal effects of SGLT2 inhibitors. Diabetes, Obesity and Metabolism, 21 (6), pp. 1291-1298.

Bailey, Clifford J. (2019). Insulin resistance:Impact on therapeutic developments in diabetes. Diabetes and Vascular Disease Research, 16 (2), pp. 128-132.

Bailey, Clifford J. and Day, Caroline (2019). The future of new drugs for diabetes management. Diabetes Research and Clinical Practice, 155 ,

Bailey, Clifford J., Del Prato, Stefano, Wei, Cheryl, Reyner, Daniel and Saraiva, Gabriela (2019). Durability of glycaemic control with dapagliflozin, an SGLT2 inhibitor, compared with saxagliptin, a DPP4 inhibitor, in patients with inadequately controlled type 2 diabetes. Diabetes, Obesity and Metabolism, 21 (11), pp. 2564-2569.

Bailey, Clifford J. and Marx, Nikolaus (2019). Cardiovascular protection in type 2 diabetes:Insights from recent outcome trials. Diabetes, Obesity and Metabolism, 21 (1), pp. 3-14.

Bashir, Amreen, Azeem, Ansar, Stedman, Yvonne and Hilton, Anthony C. (2019). Pet Food Factory Isolates of Salmonella Serotypes Do Not Demonstrate Enhanced Biofilm Formation Compared to Serotype-Matched Clinical and Veterinary Isolates. BioMed Research International, 2019 ,

Boiocchi, Federica, Davies, Matthew and Hilton, Anthony C (2019). An Examination of Flying Insects in Seven Hospitals in the United Kingdom and Carriage of Bacteria by True Flies (Diptera:Calliphoridae, Dolichopodidae, Fanniidae, Muscidae, Phoridae, Psychodidae, Sphaeroceridae). Journal of Medical Entomology, 56 (6), 1684–1697.

Brown, James (2019). Can this new anti-ageing supplement turn back the clock? The Conversation Trust (UK).

Cameron, Allan (2019). Attracted to death:apoptotic cell-derived extracellular vesicles towards a basic characterisation. PHD thesis, Aston University.

Campos-pinto, Isabel, Méndez, Lucía, Schouten, James, Wilkins, John, Fedorova, Maria, Pitt, Andrew, Davis, Paul and Spickett, Corinne (2019). Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies. Free Radical Biology and Medicine, 144 , pp. 234-244.

Capoor, Manu N, McDowell, Andrew, Raz, Assaf, Lambert, Peter and Slaby, Ondrej (2019). Letter to the Editor concerning "Low virulence bacterial infections in cervical intervertebral discs: a prospective case series" by Chen Y, Wang X, Zhang X, et al. (Eur Spine J; 2018: doi:10.1007/s00586-018-5582-4). European Spine Journal, 28 , 1242–1245.

Chapman, David, Foxcroft, Roland, Dale-Harris, Laura, Ronte, Hanno, Bidgoli, Farid and Bellary, Srikanth (2019). Insights for Care:The Healthcare Utilisation and Cost Impact of Managing Type 2 Diabetes-Associated Microvascular Complications. Diabetes Therapy, 10 (2), pp. 575-585.

Choudhery, Haris (2019). Novel collagen- based biomaterials for bone regeneration. PHD thesis, Aston University.

Connolly, James P R, O'Boyle, Nicky, Turner, Natasha C A, Browning, Douglas F and Roe, Andrew J (2019). Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor. Proceedings of the National Academy of Sciences of the United States of America, 116 (39), pp. 19695-19704.

Conway, Claire (2019). Disappearing pressure cuffs. Science Translational Medicine, 11 (476),

Costa Sousa, Bebiana, Ahmed, Tanzim, Dann, William L., Ashman, Jed, Guy, Alexandre, Durand, Thierry, Pitt, Andrew R and Spickett, Corinne M (2019). Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells. Free Radical Biology and Medicine, 144 , pp. 223-233.

Cox, Jonathan A.G., Taylor, Rebecca C., Brown, Alistair K., Attoe, Samuel, Besra, Gurdyal S. and Fütterer, Klaus (2019). Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation. Acta Crystallographica Section D: Structural Biology, 75 (Pt 1), pp. 101-108.

Da Costa Sousa, Bebiana (2019). An investigation into protein modification by short-chain lipid oxidation products:development of mass spectrometry-based approaches for their detection and assessment of the effect on cellular proteins structure and activity. PHD thesis, Aston University.

Ellis, Samuel J, Yasir, Muhammad, Browning, Douglas F, Busby, Stephen J W and Schüller, Stephanie (2019). Oxygen and contact with human intestinal epithelium independently stimulate virulence gene expression in enteroaggregative Escherichia coli. Cellular microbiology, 21 (6),

Flavell, Charlotte and Lee, Jonathan (2019). Dopaminergic D1 receptor signalling is necessary, but not sufficient for cued fear memory destabilisation. Psychopharmacology, 236 , 3667–3676.

Grant, Lois, Milic, Ivana and Devitt, Andrew (2019). Apoptotic cell-derived extracellular vesicles: structure-function relationships. Biochemical Society Transactions, 47 (2), pp. 509-516.

Guerrero Montero, Isabel, Richards, Kirsty L, Jawara, Chillel, Browning, Douglas F, Peswani, Amber R, Labrit, Mickael, Allen, Matthew, Aubry, Cedric, Davé, Emma, Humphreys, David P, Busby, Stephen J W and Robinson, Colin (2019). Escherichia coli "TatExpress" strains export several g/L human growth hormone to the periplasm by the Tat pathway. Biotechnology and Bioengineering, 116 (12), pp. 3282-3291.

Gulamhussein, Aiman A., Meah, Danyall, Soja, Damian D., Fenner, Stephen, Saidani, Zakaria, Akram, Aneel, Lallie, Simran, Mathews, Ashlyn, Painter, Culum, Liddar, Monique K., Mohammed, Zain, Ki Chiu, Lai, Sumar, Sabiha S., Healy, Hannah, Hussain, Nabeel, Patel, Jaimin H., Hall, Stephen C.l., Dafforn, Timothy R. and Rothnie, Alice J. (2019). Examining the stability of membrane proteins within SMALPs. European Polymer Journal, 112 , pp. 120-125.

Hardy, David (2019). Solubilisation and stabilisation of MRP4 using novel detergents for function and structural studies. PHD thesis, Aston University.

Hardy, David, Bill, Roslyn M, Jawhari, Anass and Rothnie, Alice J (2019). Functional expression of Multidrug Resistance Protein 4 MRP4/ABCC4. SLAS Discovery, 24 (10), pp. 1000-1008.

Hardy, David, Bill, Roslyn M, Rothnie, Alice J and Jawhari, Anass (2019). Stabilization of human Multidrug Resistance Protein 4 (MRP4/ABCC4) using novel solubilization agents. SLAS Discovery, 24 (10), pp. 1009-1017.

Harrison, James and Cox, Jonathan A. G. (2019). Changing the Rules of TB-Drug Discovery. Journal of Medicinal Chemistry, 62 (23), pp. 10583-10585.

Heitmar, Rebekka, Brown, James E and Kyrou, Ioannis (2019). Saffron (Crocus sativus L.) in ocular diseases:a narrative review of the existing evidence from clinical studies. Nutrients, 11 (3),

Ikwuobe, Ogwu John (2019). The role of odd chain fatty acids on hepatocyte and monocyte function. PHD thesis, Aston University.

Jabran, Ali, Peach, Chris, Zou, Zhenmin and Ren, Lei (2019). Parametric design optimisation of proximal humerus plates based on finite element method. Annals of Biomedical Engineering, 47 (2), 601–614.

Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J, Stewart, Grant S, Wollnik, Bernd, Yigit, Gökhan and Caldecott, Keith W (2019). Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ. Neurology Genetics, 5 (2),

Karagoz, Pınar, Bill, Roslyn M. and Ozkan, Melek (2019). Lignocellulosic ethanol production:Evaluation of new approaches, cell immobilization and reactor configurations. Renewable Energy, 143 , pp. 741-752.

Karikari, T.K., Nagel, David A, Grainger, Alastair, Clarke-Bland, Charlotte, Crowe, James, Hill, Eric J and Moffat, Kevin G. (2019). Distinct conformations, aggregation and cellular internalization of different tau strains. Frontiers in Cellular Neuroscience, 13 ,

Karikari, Thomas K., Nagel, David A., Grainger, Alastair, Clarke-bland, Charlotte, Hill, Eric J. and Moffat, Kevin G. (2019). Preparation of stable tau oligomers for cellular and biochemical studies. Analytical Biochemistry, 566 , pp. 67-74.

Khadke, Swapnil, Roces, Carla B., Cameron, Allan, Devitt, Andrew and Perrie, Yvonne (2019). Formulation and manufacturing of lymphatic targeting liposomes using microfluidics. Journal of Controlled Release, 307 , pp. 211-220.

Kilari, R. S., Bashir, A. I.j., Devitt, A., Perry, C. J., Safrany, S. T. and Nicholl, Iain D. (2019). The cytotoxicity and synergistic potential of aspirin and aspirin analogues towards oesophageal and colorectal cancer. Current Clinical Pharmacology, 14 (2), pp. 141-151.

Kitchen, Philip, Salman, Mootaz M., Pickel, Simone, Jennings, Jordan, Törnroth-horsefield, Susanna, Conner, Matthew, Bill, Roslyn and Conner, Alex C. (2019). Water channel pore size determines exclusion properties but not solute selectivity. Scientific Reports, 9 (1),

Kite, Christopher, Lahart, Ian M., Afzal, Islam, Broom, David, Randeva, Harpal Singh, Kyrou, Ioannis and Brown, James E (2019). Exercise, or exercise and diet for the management of polycystic ovary syndrome:a systematic review and meta-analysis. Systematic Reviews, 8 (1), p. 51.

Kohli, Nupur, Al-Delfi, Ibtesam R.T., Snow, Martyn, Sakamoto, Takumi, Miyazaki, Tsuyoshi, Nakajima, Hideaki, Uchida, Kenzo and Johnson, William E.B. (2019). CD271-selected mesenchymal stem cells from adipose tissue enhance cartilage repair and are less angiogenic than plastic adherent mesenchymal stem cells. Scientific Reports, 9 (1),

Lascar, Nadia, Altaf, Quratul-Ain, Raymond, Neil T, Brown, James Ep, Pattison, Helen, Barnett, Anthony, Bailey, Clifford J and Bellary, Srikanth (2019). Phenotypic characteristics and risk factors in a multi-ethnic cohort of young adults with type 2 diabetes. Current Medical Research and Opinion, 35 (11), pp. 1893-1900.

Lee, Si Yuen, George, Julian H., Nagel, David A., Ye, Hua, Kueberuwa, Gray and Seymour, Leonard W. (2019). Optogenetic control of iPS cell-derived neurons in 2D and 3D culture systems using channelrhodopsin-2 expression driven by the synapsin-1 and calcium-calmodulin kinase II promoters. Journal of Tissue Engineering and Regenerative Medicine, 13 (3), pp. 369-384.

Leyva, Francisco, Zegard, Abbasin, Okafor, Osita, De Bono, Joseph, Mcnulty, David, Ahmed, Asif, Marshall, Howard, Ray, Daniel and Qiu, Tian (2019). Survival after cardiac resynchronization therapy: results from 50 084 implantations. Europace, 21 (5), 754–762.

Liu, Jing, Qian, Zhihui, Wang, Kunyang, Wu, Jianan, Jabran, A., Ren, Luquan and Ren, Lei (2019). Non-invasive Quantitative Assessment of Muscle Force Based on Ultrasonic Shear Wave Elastography. Ultrasound in Medicine and Biology, 45 (2), pp. 440-451.

Lopeman, Rose C., Harrison, James, Desai, Maya and Cox, Jonathan A. G. (2019). Mycobacterium abscessus: Environmental Bacterium Turned Clinical Nightmare. Microorganisms, 7 (3),

Low, Floren (2019). ATP-binding cassette subfamily C (ABCC) transporter 1 (ABCC1) and 4 (ABCC4) independent of their drug efflux ability affects breast cancer biology. PHD thesis, Aston University.

Moutsatsou, P., Ochs, J., Schmitt, R. H., Hewitt, C. J. and Hanga, M. P. (2019). Automation in cell and gene therapy manufacturing:from past to future. Biotechnology Letters, 41 (11), pp. 1245-1253.

Mulla, Suhayl (2019). Mathematical modelling of hypoxia and temperature signalling pathways in lifespan. PHD thesis, Aston University.

Ni, Zhixu, Sousa, Bebiana C., Colombo, Simone, Afonso, Catarina B., Melo, Tania, Pitt, Andrew R., Spickett, Corinne M., Domingues, Pedro, Domingues, M. Rosário, Fedorova, Maria and Criscuolo, Angela (2019). Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS. Free Radical Biology and Medicine, 144 , pp. 156-166.

Nolan, Victoria C., Harrison, James and Cox, Jonathan A. G. (2019). Dissecting the Antimicrobial Composition of Honey. Antibiotics, 8 (4),

Okafor, Osita, Zegard, Abbasin, Van Dam, Peter, Stegemann, Berthold, Qiu, Tian, Marshall, Howard and Leyva, Francisco (2019). Changes in QRS Area and QRS Duration After Cardiac Resynchronization Therapy Predict Cardiac Mortality, Heart Failure Hospitalizations, and Ventricular Arrhythmias. Journal of the American Heart Association, 8 (21),

Pallett, Ross (2019). Using an in vitro model of human cystic fibrosis airways to investigate bacterial strategies which inactivate defence mechanisms and increase infection. PHD thesis, Aston University.

Pallett, Ross, Leslie, Laura J., Lambert, Peter. A., Milic, Ivana, Devitt, Andrew and Marshall, Lindsay J. (2019). Anaerobiosis influences virulence properties of Pseudomonas aeruginosa cystic fibrosis isolates and the interaction with Staphylococcus aureus. Scientific Reports, 9 (1),

Perkovic, Vlado, Jardine, Meg J., Neal, Bruce, Bompoint, Severine, Heerspink, Hiddo J.l., Charytan, David M., Edwards, Robert, Agarwal, Rajiv, Bakris, George, Bull, Scott, Cannon, Christopher P., Capuano, George, Chu, Pei-ling, De Zeeuw, Dick, Greene, Tom, Levin, Adeera, Pollock, Carol, Wheeler, David C., Yavin, Yshai, Zhang, Hong, Zinman, Bernard, Meininger, Gary, Brenner, Barry M., Mahaffey, Kenneth W. and Bellary, Srikanth (2019). Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. New England Journal of Medicine, 380 (24), pp. 2295-2306.

Pollock, Naomi L., Rai, Megha, Simon, Kailene S., Hesketh, Sophie J., Teo, Alvin C.k., Parmar, Mayuriben, Sridhar, Pooja, Collins, Richard, Lee, Sarah C., Stroud, Zoe N., Bakker, Saskia E., Muench, Stephen P., Barton, C. Howard, Hurlbut, Gregory, Roper, David I., Smith, Corinne J.i., Knowles, Timothy J., Spickett, Corinne M., East, J. Malcolm, Postis, Vincent and Dafforn, Tim R. (2019). SMA-PAGE: A new method to examine complexes of membrane proteins using SMALP nano-encapsulation and native gel electrophoresis. BBA -Biomembranes, 1861 (8), pp. 1437-1445.

Raja, Farah N.s., Worthington, T., Isaacs, Mark A., Rana, Karan S. and Martin, Richard A. (2019). The antimicrobial efficacy of zinc doped phosphate-based glass for treating catheter associated urinary tract infections. Materials Science and Engineering C, 103 ,

Raja, Farah, Worthington, Anthony, Isaacs, Mark, Forto Chungong, Louis, Burke, Bernard, Addison, Owen and Martin, Richard A (2019). The antimicrobial efficacy of hypoxia mimicking cobalt oxide doped phosphate-based glasses against clinically relevant Gram positive, Gram negative bacteria and a fungal strain. ACS Biomaterials Science and Engineering, 5 (1), 283–293.

Remtulla, Ali Hussein (2019). Reactive oxygen species in protein sulphenic acid formation during T cell activation; implications for rheumatoid arthritis. PHD thesis, Aston University.

Repici, Mariaelena and Giorgini, Flaviano (2019). DJ-1 in Parkinson’s Disease: Clinical Insights and Therapeutic Perspectives. Journal of Clinical Medicine, 8 (9),

Rong Tay, Kai, Law, Charlotte, Cassini, Lindsey F., Wimber, Maria and Lee, Jonathan (2019). Postretrieval Relearning Strengthens Hippocampal Memories via Destabilization and Reconsolidation. Journal of Neuroscience, 39 (6), pp. 1109-1118.

Rossin, D., Dias, I.h.k., Solej, M., Milic, I., Pitt, A.r., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H.r., Spickett, C.m., Poli, G. and Biasi, F. (2019). Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration. Free Radical Biology and Medicine, 136 , pp. 35-44.

Routledge, Sarah J., Linney, John A. and Goddard, Alan D. (2019). Liposomes as models for membrane integrity. Biochemical Society Transactions, 47 (3), pp. 919-932.

Santiago-toledo, Gerardo, Georgiou, Melanie, Dos Reis, Joana, Roberton, Victoria H., Valinhas, Ana, Wood, Rachael C., Phillips, James B., Mason, Chris, Li, Daqing, Li, Ying, Sinden, John D., Choi, David, Jat, Parmjit S. and Wall, Ivan B. (2019). Generation of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications. Scientific Reports, 9 (1),

Sobczak, Maciej, Pitt, Andrew R, Spickett, Corinne M and Robaszkiewicz, Agnieszka (2019). PARP1 Co-regulates EP300–BRG1-dependent transcription of genes involved in breast cancer cell proliferation and DNA repair. Cancers, 11 (10),

Teo, Alvin C. K., Lee, Sarah C., Pollock, Naomi L., Stroud, Zoe, Hall, Stephen, Thakker, Alpesh, Pitt, Andrew R., Dafforn, Timothy R., Spickett, Corinne M. and Roper, David I. (2019). Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein. Scientific Reports, 9 (1),

Trotter, Katherine D., Owojaiye, Olawale, Meredith, Stuart, Keating, Pat E., Spicer, Mark D., Reglinski, John and Spickett, Corinne M (2019). The interaction of silver(II) complexes with biological macromolecules and antioxidants. BioMetals, 32 (4), pp. 627-640.

Vernon, D., Brown, James E, Griffiths, E., Nevill, Alan M. and Pinkney, M. (2019). Reducing readmission rates through a discharge follow-up service. Future Healthcare Journal, 6 (2), pp. 114-117.

Yasir, Muhammad, Icke, Christopher, Abdelwahab, Radwa, Haycocks, James R, Godfrey, Rita E, Sazinas, Pavelas, Pallen, Mark J, Henderson, Ian R, Busby, Stephen J W and Browning, Douglas F (2019). Organization and architecture of AggR-dependent promoters from enteroaggregative Escherichia coli. Molecular Microbiology, 111 (2), pp. 534-551.

Zafar, Ali, Lee, Jou, Yesmin, Shameema, Paget, Michelle B., Bailey, Clifford J., Murray, Hilary E. and Downing, Richard (2019). Rotational culture and integration with amniotic stem cells reduce porcine islet immunoreactivity in vitro and slow xeno‐rejection in a murine model of islet transplantation. Xenotransplantation, 26 (4),