Items where Division is "College of Health & Life Sciences > School of Biosciences" and Year is 2016

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Al Delfi, I.R., Sheard, J.J., Wood, C.R., Vernallis, A., Innes, J.F., Myint, P. and Johnson, W.E.B. (2016). Canine mesenchymal stem cells are neurotrophic and angiogenic:an in vitro assessment of their paracrine activity. Veterinary Journal, 217 , pp. 10-17.

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Bailey, Clifford J., Tahrani, Abd A. and Barnett, Anthony H. (2016). Future glucose-lowering drugs for type 2 diabetes. The Lancet Diabetes and Endocrinology, 4 (4), pp. 350-359.

Balklava, Zita, Rathnakumar, Navin D., Vashist, Shilpa, Schweinsberg, Peter J. and Grant, Barth D. (2016). Linking gene expression in the intestine to production of gametes through the phosphate transporter PITR-1 in Caenorhabditis elegans. Genetics, 204 (1), pp. 153-162.

Bashir, Amreen (2016). Exploring the biological basis for Salmonella persistence in food manufacturing environments. PHD thesis, Aston University.

Begum, Saima, Johnson, Eustace, Worthington, Tony and Martin, Richard A. (2016). The influence of pH and fluid dynamics on the antibacterial efficacy of 45S5 Bioglass. Biomedical Materials, 11 (1),

Bilkhu, Paramdeep, Wolffsohn, James S., Hilton, Anthony, Matthews, Gabrielle, Legood, Simon and Riley, Liam (2016). Microwave decontamination of eyelid warming devices for the treatment of meibomian gland dysfunction. Contact Lens and Anterior Eye, 39 (4), 293–297.

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Chen, Xianfeng, Liu, Chen, Cardoso, Marcos R., Mendonça, Cleber R., Nagel, David A., Hine, Anna V. and Zhang, Lin (2016). Label-free oligonucleotide biosensor based on dual-peak long period fiber grating. IN: Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI. Gannot, Israel (ed.) SPIE Proceedings . USA: SPIE.

Christie, Jamieson K., Cormack, Alastair N., Hanna, John V., Martin, Richard A., Newport, Robert J., Pickup, David M. and Smith, Mark E. (2016). Bioactive sol-gel glasses at the atomic scale:the complementary use of advanced probe and computer modeling methods. International Journal of Applied Glass Science, 7 (2), 147–153.

Currinn, Heather, Guscott, Benjamin, Balklava, Zita, Rothnie, Alice and Wassmer, Thomas (2016). APP controls the formation of PI(3,5)P2 vesicles through its binding of the PIKfyve complex. Cellular and Molecular Life Sciences, 73 (2), pp. 393-408.

Currinn, Heather and Wassmer, Thomas (2016). The amyloid precursor protein (APP) binds the PIKfyve complex and modulates its function. Biochemical Society Transactions, 44 (1), pp. 185-190.

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Davies, M.P., Anderson, M. and Hilton, A.C. (2016). The housefly Musca domestica as a mechanical vector of Clostridium difficile. Journal of Hospital Infection, 94 (3), pp. 263-267.

Denisenko, Oleg, Lucas, Emma S., Sun, Congshan, Watkins, Adam J., Mar, Daniel, Brmsztyk, Karol and Fleming, Tom P. (2016). Regulation of ribosomal RNA expression across the lifespan is fine-tuned by maternal diet before implantation. BBA Gene Regulatory Mechanisms, 1859 (7), 906–913.

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Gascoyne, Lauren, Furlong, Paul L., Hillebrand, Arjan, Worthen, Siân F. and Witton, Caroline (2016). Localising the auditory N1m with event-related beamformers:localisation accuracy following bilateral and unilateral stimulation. Scientific Reports, 6 ,

Gingell, Joseph J., Simms, John, Barwell, James, Poyner, David R., Watkins, Harriet A., Pioszak, Augen A., Sexton, Patrick M. and Hay, Debbie L. (2016). An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology. Cell Discovery, 2 ,

Guscott, Benjamin (2016). Investigating novel interaction partners of amyloid precursor protein: the mechanistic target of rapamycin and pikyve complex. PHD thesis, Aston University.

Guscott, Benjamin, Balklava, Zita, Safrany, Stephen T. and Wassmer, Thomas (2016). A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity. Bioscience Reports, 36 (2),

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Hardy, David, Bill, Roslyn M., Jawhari, Anass and Rothnie, Alice J. (2016). Overcoming bottlenecks in the membrane protein structural biology pipeline. Biochemical Society Transactions, 44 (3), pp. 838-844.

Hill, Eric, Nagel, David, Parri, Rheinallt and Coleman, Michael (2016). Stem cell-derived astrocytes:are they physiologically credible? Journal of Physiology, 594 (22), pp. 6595-6606.

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Jabran, A., Ren, Lei, Peach, C. and Zou, Z. (2016). A Methodology for Biomechanical Assessment of Proximal Humerus Fractures Using an Integrated Experimental and Computational Framework. Procedia CIRP, 49 , pp. 139-142.

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Killick, Justin (2016). An investigation into the effects of metabolic disturbance on monocyte inflammatory response and regulation. PHD thesis, Aston University.

Kiraly, Robert, Thangaraju,, Kiruphagaran, Nagy, Zsófia, Collighan, Russell, Nemes, Zoltán, Griffin, Martin and Fésüs, László (2016). Isopeptidase activity of human transglutaminase 2:disconnection from transamidation and characterization by kinetic parameters. Amino Acids, 48 (1), pp. 31-40.

Kitchen, Philip, Conner, Matthew T., Bill, Roslyn M. and Conner, Alex C. (2016). Structural determinants of oligomerization of the aquaporin-4 channel. Journal of Biological Chemistry, 291 (13), pp. 6858-6871.

Kohli, Nupur (2016). An investigation of primary human cell sources and clinical scaffolds for articular cartilage repair. PHD thesis, Aston University.

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Lattmann, E., Russell, S.T., Schwalbe, C.H., Shortt, A., Balaram, P.N., Theochari, E., Alharbi, M., Narayanan, R. and Lattmann, P. (2016). Cholecystokinin-1 receptor antagonists:5-hydroxy-5-aryl-pyrrol-2-ones as anticancer agents. MedChemComm, 7 (6), pp. 1138-1145.

Lee, Sarah C., Khalid, Syma, Pollock, Naomi L., Knowles, Timothy J., Edler, Karen, Rothnie, Alice J., Thomas, Owen R.T. and Dafforn, Timothy R. (2016). Encapsulated membrane proteins: a simplified system for molecular simulation. BBA -Biomembranes, 1858 (10), pp. 2549-2557.

Litvinova, Karina S., Ahmad, Shakil, Wang, Keqing, Rafailov, Ilya E., Sokolovski, Sergei G., Zhang, Lin, Rafailov, Edik U. and Ahmed, Asif (2016). A pilot study using laser-based technique for non-invasive diagnostics of hypertensive conditions in mice. Proceedings of SPIE - International Society for Optical Engineering, 9689 ,

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McCreight, Laura J., Bailey, Clifford J. and Pearson, Ewan R. (2016). Metformin and the gastrointestinal tract. Diabetologia, 59 (3), pp. 426-435.

Meredith, Stuart (2016). Biotechnology for detecting oxidative modifications to fibrinogen. PHD thesis, Aston University.

Morrison, Kerrie A., Akram, Aneel, Mathews, Ashlyn, Khan, Zoeya A., Patel, Jaimin H., Zhou, Chumin, Hardy, David John, Moore-Kelly, Charles, Patel, Roshani, Odiba, Victor, Knowles, Tim, Javed, Masood-ul-Hassan, Chmel, Nikola P., Dafforn, Timothy R. and Rothnie, Alice Jane (2016). Membrane protein extraction and purification using styrene-maleic acid (SMA) co-polymer:effect of variations in polymer structure. Biochemical Journal, 473 (23), pp. 4349-4360.

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Nguyen, Duc Bach, Thuy Ly, Thi Bich, Wesseling, Mauro Carlos, Hittinger, Marius, Torge, Afra, Devitt, Andrew, Perrie, Yvonne and Bernhardt, Ingolf (2016). Characterization of microvesicles released from human red blood cells. Cellular Physiology and Biochemistry, 38 (3), pp. 1085-1099.

Nyabam, Samuel, Wang, Zhuo, Thibault, Thomas, Ayinde, Oluseyi, Basar, Rameeza, Marshall, Lindsay and Griffin, Martin (2016). A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis. BBA - Molecular Cell Research, 1863 (9), pp. 2234-2244.

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Pararasa, Chathyan, Ikwuobe, John, Shigdar, Shahjahan, Boukouvalas, Alexis, Nabney, Ian T., Brown, James E., Devitt, Andrew, Bailey, Clifford J., Bennett, Stuart J. and Griffiths, Helen R. (2016). Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ. Aging Cell, 15 (1), pp. 128-139.

Pasha, Sabah (2016). The role of protein oxidation in ageing & disease. PHD thesis, Aston University.

Patel, Sunni R., Bellary, Srikanth, Karimzad, Said and Gherghel, Doina (2016). Overweight status is associated with extensive signs of microvascular dysfunction and cardiovascular risk. Scientific Reports, 6 ,

Perrie, Yvonne, Crofts, Fraser, Devitt, Andrew, Griffiths, Helen R, Kastner, Elisabeth and Nadella, Vinod (2016). Designing liposomal adjuvants for the next generation of vaccines. Advanced Drug Delivery Reviews, 99 (Part A), pp. 85-96.

Poole, Andrew (2016). The integration of ProxiMAX randomisation with CIS display for the production of novel peptides. PHD thesis, Aston University.

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Rana, Karan (2016). The metabolic regulation of cellular ageing. PHD thesis, Aston University.

Rathnakumar, Navin David (2016). Role of fibroblast growth factor receptor in regulation of membrane traffic. PHD thesis, Aston University.

Routledge, Sarah, Mikaliunaite, Lina, Patel, Anjana, Clare, Michelle, Cartwright, Stephanie P., Bawa, Zharain, Wilks, Martin D.B., Low, Floren, Hardy, David, Rothnie, Alice J. and Bill, Roslyn M. (2016). The synthesis of recombinant membrane proteins in yeast for structural studies. Methods, 95 , pp. 26-37.

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Sasso, Ferdinando Carlo, Lascar, Nadia, Ascione, Antonella, Carbonara, Ornella, de Nicola, Luca, Minutolo, Roberto, Salvatore, Teresa, Rizzo, Maria Rosaria, Cirillo, Plinio, Paolisso, Giuseppe, Marfella, Raffaele and on behalf of NID-2 study group (2016). Moderate-intensity statin therapy seems ineffective in primary cardiovascular prevention in patients with type 2 diabetes complicated by nephropathy:a multicenter prospective 8 years follow up study. Cardiovascular Diabetology, 15 (1),

Sharma, Shruti (2016). Assessing the physiological and pathological functions of tissue Transglutaminase using FRET analysis. PHD thesis, Aston University.

Sheard, Jonathan (2016). Screening and improving the safe provision of mesenchymal stem cells in regenerative medicine: an in vitro study. PHD thesis, Aston University.

Sinclair, Alan J. and Bellary, Srikanth (2016). Preventing hypoglycaemia:an elusive quest. The Lancet Diabetes and Endocrinology, 4 (8), pp. 635-636.

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Tahrani, Abd A., Barnett, Anthony H. and Bailey, Clifford J. (2016). Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus. Nature Reviews Endocrinology, 12 (10), 566–592.

Tata, Mathew, Wall, Ivan, Joyce, Andy, Vieira, Joaquim M, Kessaris, Nicoletta and Ruhrberg, Christiana (2016). Regulation of embryonic neurogenesis by germinal zone vasculature. Proceedings of the National Academy of Sciences of the United States of America, 113 (47), pp. 13414-13419.

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Verrastro, Ivan, Tveen-Jensen, Karina, Woscholski, Rudiger, Spickett, Corinne M. and Pitt, Andrew R. (2016). Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins. Free Radical Biology and Medicine, 90 , pp. 24-34.

van den Berg, Bert, Chembath, Anupama, Jefferies, Damien, Basle, Arnaud, Khalid, Syma and Rutherford, Julian C (2016). Structural basis for Mep2 ammonium transceptor activation by phosphorylation. Nature Communications, 7 ,

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Ward, Stephen T, Weston, Christopher J, Shepherd, Emma Louise, Hejmadi, Rahul, Ismail, Tariq and Adams, David H. (2016). Evaluation of serum and tissue levels of VAP-1 in colorectal cancer. BMC Cancer, 16 ,

Watanabe, Yosuke, Murdoch, Colin E., Sano, Soichi, Ido, Yasuo, Bachschmid, Markus M., Cohen, Richard A. and Matsui, Reiko (2016). Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1α and improve limb revascularization. Proceedings of the National Academy of Sciences, 113 (21), pp. 6011-6016.

Watkins, Harriet A., Chakravarthy, Madhuri, Abhayawardana, Rekhati S., Gingell, Joseph J., Garelja, Michael, Pardamwar, Meenakshi, McElhinney, James M.W.R., Lathbridge, Alex, Constantine, Arran, Harris, Paul W.R., Yuen, Tsz-Ying, Brimble, Margaret A., Barwell, James, Poyner, David R., Woolley, Michael J., Conner, Alex C., Pioszak, Augen A., Reynolds, Christopher A. and Hay, Debbie L. (2016). Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties. Journal of Biological Chemistry, 291 (22), pp. 11657-11675.

Wheatley, Mark, Charlton, Jack, Jamshad, Mohammed, Routledge, Sarah J., Bailey, Sian, La-Borde, Penelope J., Azam, Maria T., Logan, Richard T., Bill, Roslyn M., Dafforn, Tim R. and Poyner, David R. (2016). GPCR-styrene maleic acid lipid particles (GPCR-SMALPs):their nature and potential. Biochemical Society Transactions, 44 (2), pp. 619-623.

Wilding, John, Bailey, Clifford, Rigney, Una, Blak, Betina, Beekman, Wendy and Emmas, Cathy (2016). Glycated hemoglobin, body weight and blood pressure in type 2 diabetes patients initiating dapagliflozin treatment in primary care:a retrospective study. Diabetes Therapy, 7 (4), pp. 695-711.

Wilhelm, Annika, Shepherd, Emma L, Amatucci, Aldo, Munir, Mamoona, Reynolds, Gary, Humphreys, Elizabeth, Resheq, Yazid, Adams, David H, Hübscher, Stefan, Burkly, Linda C, Weston, Christopher J and Afford, Simon C (2016). Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation. Journal of Pathology, 239 (1), pp. 109-21.

Williams, David J., Archer, Richard, Archibald, Peter, Bantounas, Ioannis, Baptista, Ricardo, Barker, Roger, Barry, Jacqueline, Bietrix, Florence, Blair, Nicholas, Braybrook, Julian, Campbell, Jonathan, Canham, Maurice, Chandra, Amit, Foldes, Gabor, Gilmanshin, Rudy, Girard, Mathilde, Gorjup, Erwin, Hewitt, Zöe, Hourd, Paul, Hyllner, Johan, Jesson, Helen, Kee, Jasmin, Kerby, Julie, Kotsopoulou, Nina, Kowalski, Stanley, Leidel, Chris, Marshall, Damian, Masi, Louis, McCall, Mark, McCann, Conor, Medcalf, Nicholas, Moore, Harry, Ozawa, Hiroki, Pan, David, Parmar, Malin, Plant, Anne L., Reinwald, Yvonne, Sebastian, Sujith, Stacey, Glyn, Thomas, Robert J., Thomas, Dave, Thurman-Newell, Jamie, Turner, Marc, Vitillio, Loriana, Wall, Ivan, Wilson, Alison, Wolfrum, Jacqueline, Yang, Ying and Zimmerman, Heiko (2016). Comparability:Manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. Regenerative medicine, 11 (5), pp. 483-492.

Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C., Koole, Cassandra, Savage, Emilia E., Pabreja, Kavita, Simms, John, Sridhar, Rohan, Furness, Sebastian G.B., Liu, Mengjie, Thompson, Philip E., Miller, Laurence J., Christopoulos, Arthur and Sexton, Patrick M. (2016). The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism. Cell, 165 (7), pp. 1632-1643.

Worthington, Tony and Hilton, Anthony C. (2016). Sporulation of Clostridium difficile in aerobic conditions is significantly protracted when exposed to sodium taurocholate. Journal of Medical Microbiology & Diagnosis, 5 (2),

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Yu, Hye-Sun, Kim, Jung-Ju, Kim, Hae-Won, Lewis, Mark P and Wall, Ivan (2016). Impact of mechanical stretch on the cell behaviors of bone and surrounding tissues. Journal of Tissue Engineering, 7 ,