Browse by Aston Author

Rajabi, Anthony, Idrees, Muhammed, Rahman, Ayesha, Iyire, Affiong, Wyatt, David, Koner, Jasdip and Mohammed, Afzal R. (2024). Evaluating the role of amino acids and isothermal dry particle coating in modulating buccal permeation of large molecule drug vancomycin. Scientific Reports, 14 (1),

Burhanuddin, Khairulanwar, Mohammed, Afzal and Badhan, Raj K.S. (2024). The Impact of Paediatric Obesity on Drug Pharmacokinetics:A Virtual Clinical Trials Case Study with Amlodipine. Pharmaceutics, 16 (4),

Michaelides, Kyprianos, Prasanna, Maruthi, Badhan, Raj, Mohammed, Afzal-Ur-Rahman, Walters, Adam, Howard, M. Keith, Dulal, Pawan and Al-Khattawi, Ali (2023). Single administration vaccines: delivery challenges, in vivo performance, and translational considerations. Expert Review of Vaccines, 22 (1), pp. 579-595.

Khan, Dilawar, Badhan, Raj, Kirby, Daniel J., Bryson, Simon, Shah, Maryam and Mohammed, Afzal Rahman (2023). Virtual Clinical Trials Guided Design of an Age-Appropriate Formulation and Dosing Strategy of Nifedipine for Paediatric Use. Pharmaceutics, 15 (2),

Abiona, Olaitan, Wyatt, David, Koner, Jasdip and Mohammed, Afzal (2022). The Optimisation of Carrier Selection in Dry Powder Inhaler Formulation and the Role of Surface Energetics. Biomedicines, 10 (11),

Khan, Dilawar, Kirby, Daniel, Bryson, Simon, Shah, Maryam and Rahman Mohammed, Afzal (2022). Paediatric specific dosage forms: Patient and formulation considerations. International Journal of Pharmaceutics, 616 ,

Ftuwi, Habtom, Parri, Rheinallt and Mohammed, Afzal R. (2021). Novel, Fully Characterised Bovine Taste Bud Cells of Fungiform Papillae. Cells, 10 (9),

Khan, Dilawar, Kirby, Daniel, Bryson, Simon, Shah, Maryam and Mohammed, Afzal Rahman (2021). Development of an Age-Appropriate Mini Orally Disintegrating Carvedilol Tablet with Paediatric Biopharmaceutical Considerations. Pharmaceutics, 13 (6),

Warraich, Annsar Ahmad, Mohammed, Afzal Ur Rahman, Gibson, Hazel, Hussain, Majad and Rahman, Ayesha Sabah (2021). Acidic amino acids as counterions of ciprofloxacin:Effect on growth and pigment production in Staphylococcus aureus NCTC 8325 and Pseudomonas aeruginosa PAO1. PLoS ONE, 16 (4),

Ershad, Abdul, Rajabi-Siahboomi, Ali, Missaghi, Shahrzad, Kirby, Daniel J and Mohammed, Afzal-Ur-Rahman (2021). Multi-Analytical Framework to Assess the In Vitro Swallowability of Solid Oral Dosage Forms Targeting Patient Acceptability and Adherence. Pharmaceutics, 13 (3),

Russell, Craig, Hussain, Majad, Huen, David, Rahman, Ayesha S and Mohammed, Afzal (2021). Profiling gene expression dynamics underpinning conventional testing approaches to better inform pre-clinical evaluation of an age appropriate spironolactone formulation. Pharmaceutical Development and Technology, 26 (1), pp. 101-109.

Dennison, Thomas J, Smith, Julian C, Badhan, Raj K S and Mohammed, Afzal R (2020). Formulation and Bioequivalence Testing of Fixed-Dose Combination Orally Disintegrating Tablets for the Treatment of Tuberculosis in the Paediatric Population. Journal of Pharmaceutical Sciences, 109 (10), pp. 3105-3113.

Idrees, Muhammad, Mohammad, Afzal R., Karodia, Nazira and Rahman, Ayesha (2020). Multimodal role of amino acids in microbial control and drug development. Antibiotics, 9 (6),

Warraich, Annsar A., Mohammed, Afzal R., Perrie, Yvonne, Hussain, Majad, Gibson, Hazel and Rahman, Ayesha (2020). Evaluation of anti-biofilm activity of acidic amino acids and synergy with ciprofloxacin on Staphylococcus aureus biofilms. Scientific Reports, 10 (1),

Koner, Jasdip, Rajabi-Siahboomi, Ali, Missaghi, S., Kirby, Daniel J, Perrie, Yvonne, Ahmed, J. and Mohammed, Afzal (2019). Conceptualisation, Development, Fabrication and In Vivo Validation of a Novel Disintegration Tester for Orally Disintegrating Tablets. Scientific Reports, 9 ,

Le, Tuan-tu, Elzhry Elyafi, Abdul Khaliq, Mohammed, Afzal R. and Al-khattawi, Ali (2019). Delivery of Poorly Soluble Drugs via Mesoporous Silica: Impact of Drug Overloading on Release and Thermal Profiles. Pharmaceutics, 11 (6),

Pollard, John, Rajabi-siahboomi, Ali, Badhan, Raj K. S., Mohammed, Afzal R. and Perrie, Yvonne (2019). High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport. Journal of Pharmacy and Pharmacology, 71 (6), pp. 889-897.

Dahmash, Eman Z, Al-Khattawi, Ali, Iyire, Affiong, Al-Yami, Hamad, Dennison, Thomas J and Mohammed, Afzal R (2018). Quality by Design (QbD) based process optimisation to develop functionalised particles with modified release properties using novel dry particle coating technique. PLoS ONE, 13 (11),

Iyrie, Affiong, Russell, Craig, Dennision, Tom, Rajoli, Rajith, Saleem, Imran Y., Rahman, Ayesha S and Mohammed, Afzal (2018). Development, Optimisation, Validation and Inter-Laboratory Verification of a Reversed Phase HPLC Method for Quantification of Human Recombinant Insulin. Journal of Advances in Biotechnology, 7 , pp. 984-998.

Alyami, Hamad, Koner, Jasdip, Huynh, Chi, Terry, David and Mohammed, Afzal R. (2018). Current opinions and recommendations of paediatric healthcare professionals - The importance of tablets:Emerging orally disintegrating versus traditional tablets. PLoS ONE, 13 (2),

ElShaer, Amr, Al-Khattawi, Ali, Mohammed, Afzal R., Warzecha, Monika, Lamprou, Dimitrios A. and Hassanin, Hany (2018). Understanding the compaction behaviour of low-substituted HPC:macro, micro, and nano-metric evaluations. Pharmaceutical Development and Technology, 23 (5), pp. 442-453.

Alyami, Hamad, Dahmash, Eman, Alyami, Fahad, Dahmash, Dania, Huynh, Chi, Terry, David and Mohammed, Afzal R. (2017). Dosage form preference consultation study in children and young adults:paving the way for patient-centred and patient-informed dosage form development. European Journal of Hospital Pharmacy, 24 , pp. 332-337.

Tawfeek, Hesham M., Abdellatif, Ahmed A.H., Dennison, Thomas J., Mohammed, Afzal R., Sadiq, Younis and Saleem, Imran Y. (2017). Colonic delivery of indometacin loaded PGA-co-PDL microparticles coated with Eudragit L100-55 from fast disintegrating tablets. International Journal of Pharmaceutics, 531 (1), pp. 80-89.

Alyami, Hamad, Koner, Jasdip, Dahmash, Eman Z., Bowen, James, Terry, David and Mohammed, Afzal R. (2017). Microparticle surface layering through dry coating:impact of moisture content and process parameters on the properties of orally disintegrating tablets. Journal of Pharmacy and Pharmacology, 69 (7), 807–822.

Alyami, Hamad, Dahmash, Eman, Bowen, James and Mohammed, Afzal (2017). An investigation into the effects of excipient particle size, blending techniques and processing parameters on the homogeneity and content uniformity of a blend containing low-dose model drug. PLoS ONE, 12 (6),

Dennison, Thomas J., Smith, Julian C, Badhan, Raj K. and Mohammed, Afzal R. (2017). Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease:formulation, in vitro characterization and physiologically based pharmacokinetic modelling to assess bioavailability. Drug Design, Development and Therapy, 11 , pp. 811-826.

Iyrie, Affiong, Alayedi, Maryam and Mohammed, Afzal R. (2016). Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers. Scientific Reports, 6 ,

Dennison, Thomas J., Smith, Julian, Hofmann, Michael P., Bland, Charlotte E., Badhan, Raj K., Al-Khattawi, Ali and Mohammed, Afzal R. (2016). Design of experiments to study the impact of process parameters on droplet size and development of non-invasive imaging techniques in tablet coating. PLoS ONE, 11 (8),

Dahmash, Eman Z. and Mohammed, Afzal R. (2016). Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug delivery. Drug Discovery Today, 21 (4), pp. 550-561.

Koner, Jasdip S., Rajabi-Siahboomi, Ali, Bowen, James, Perrie, Yvonne, Kirby, Daniel and Mohammed, Afzal R. (2015). A holistic multi evidence approach to study the fragmentation behaviour of crystalline mannitol. Scientific Reports, 5 ,

ElShaer, Amr, Kaialy, Waseem, Akhtar, Noreen, Iyrie, Affiong, Hussain, Tariq, Alany, Raid and Mohammed, Afzal R. (2015). A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets. European Journal of Pharmaceutics and Biopharmaceutics, 96 , 272–281.

Al-Khattawi, Ali, Koner, Jasdip, Rue, Peter, Kirby, Dan, Perrie, Yvonne, Rajabi-Siahboomi, Ali and Mohammed, Afzal R. (2015). A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance. European Journal of Pharmaceutics and Biopharmaceutics, 94 , pp. 1-10.

Dahmash, Eman Z. and Mohammed, Afzal R. (2015). Functionalised particles using dry powder coating in pharmaceutical drug delivery:promises and challenges. Expert Opinion on Drug Delivery, 12 (12), pp. 1867-1879.

Russell, Craig, Begum, Sumyra, Hussain, Yasar, Hussain, Majad, Huen, David, Rahman, Ayesha S, Perrie, Yvonne and Mohammed, Afzal R. (2015). Paediatric drug development of ramipril:reformulation, in vitro and in vivo evaluation. Journal of Drug Targeting, 23 (9), pp. 854-863.

Al-Khattawi, Ali, Alyami, Hamad, Townsend, Bill, Ma, Xianghong and Mohammed, Afzal R. (2014). Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets. PLoS ONE, 9 (7),

Al-Khattawi, Ali, Iyire, Affiong, Dennison, Tom, Dahmash, Eman, Bailey, Clifford J, Smith, Julian, Rue, Peter and Mohammed, Afzal R. (2014). Systematic screening of compressed ODT excipients : cellulosic versus non-cellulosic. Current drug delivery, 11 , pp. 1-15.

Ali, M. Habib, Moghaddam, Behfar, Kirby, Daniel J., Mohammed, Afzal R. and Perrie, Yvonne (2013). The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs. International Journal of Pharmaceutics, 453 (1), pp. 225-232.

Russell, Craig, Rahman, Ayesha and Mohammed, Afzal R. (2013). Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic delivery, 4 (3), pp. 395-413.

ElShaer, Amr, Hanson, Peter, Worthington, Tony, Lambert, Peter and Mohammed, Afzal R. (2012). Preparation and characterisation of amino acids based trimethoprim salts. Pharmaceutics, 4 (1), pp. 179-196.

Ali, M. Habib, Moghaddam, Behfar, Kirby, Daniel J., Mohammed, Afzal R. and Perrie, Yvonne (2012). The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs. International journal of pharmaceutics, in pre ,

Moghaddam, Behfar, McNeil, Sarah E., Zheng, Qinguo, Mohammed, Afzal R. and Perrie, Yvonne (2011). Exploring the correlation between lipid packaging in lipoplexes and their transfection efficacy. Pharmaceutics, 3 (4), pp. 848-864.

Jones, Rhys J., Rajabi-Siahboomi, Ali, Levina, Marina, Perrie, Yvonne and Mohammed, Afzal R. (2011). The influence of formulation and manufacturing process parameters on the characteristics of lyophilized orally disintegrating tablets. Pharmaceutics, 3 (3), pp. 440-457.

Shabir, Anjumn, Alhusban, Farhan, Perrie, Yvonne and Mohammed, Afzal R. (2011). Effects of ball-milling on PLGA polymer and its implication on lansoprazole-loaded nanoparticles. Journal of Basic and Clinical Pharmacy, 2 (2), pp. 71-82.

AlHusban, Farhan, Elshaer, Amr M., Kansara, Jiteen H., Smith, Alan M., Grover, Liam M., Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman (2010). Investigation of formulation and process of lyophilised orally disintegrating tablet (ODT) using novel amino acid combination. Pharmaceutics, 2 (1), pp. 1-17.

Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman (2009). Pharmaceutics:a new open-access journal for all those interested in designing medicines. Pharmaceutics, 1 (1), pp. 1-2.

Mohammed, Afzal U. R. (2005). Solubility enhancement of poorly water soluble drugs using liposome technology. PHD thesis, Aston University.