Items where Division is "College of Health & Life Sciences > School of Biosciences" and Year is 2014

A

Adams, Eric F., Goto, Yukie, Dai, Niann-Tzyy and Evans, Mark (2014). Receptor for activated C Kinase 1 protein binds to and activates the human estrogen receptor α. Journal of Medical Sciences, 34 (2), pp. 52-55.

Al-Khattawi, Ali, Iyire, Affiong, Dennison, Tom, Dahmash, Eman, Bailey, Clifford J, Smith, Julian, Rue, Peter and Mohammed, Afzal R. (2014). Systematic screening of compressed ODT excipients : cellulosic versus non-cellulosic. Current drug delivery, 11 , pp. 1-15.

Alghareeb, Khaled, Nadella, Vinod, Bland, Charlotte E. and Devitt, Andrew (2014). Characterisation of ICAM-3 and extracellular vesicles in the clearance of apoptotic cells. IN: British Society for Immunology (BSI) annual congress. UK, 2014-12-01 - 2014-12-04.

Arif, Muhammad (2014). The Role of Aquaporin 3 (AQP3) in Breast Cancer. PHD thesis, Aston University.

B

Bawa, Zharain (2014). Improving recombinant human adenosine A2A receptor production in yeast. PHD thesis, Aston University.

Bawa, Zharain, Routledge, Sarah J., Jamshad, Mohammed, Clare, Michelle, Sarkar, Debasmita, Dickerson, Ian, Ganzlin, Markus, Poyner, David R. and Bill, Roslyn M. (2014). Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. Microbial Cell Factories, 13 (1),

Bill, Roslyn M. (2014). Playing catch-up with Escherichia coli:using yeast to increase success rates in recombinant protein production experiments. Frontiers in Microbiology, 5 ,

Bobat, Saeeda, Darby, Matthew, Mrdjen, Dunja, Cook, Charlotte, Logan, Erin, Auret, Jennifer, Jones, Elizabeth, Schnoeller, Corinna, Flores-Langarica, Adriana, Ross, Ewan A., Vira, Alykhan, López-Macías, Constantino, Henderson, Ian R., Alexander, James, Brombacher, Frank, Horsnell, William G. and Cunningham, Adam F. (2014). Natural and Vaccine-Mediated Immunity to Salmonella Typhimurium is Impaired by the Helminth Nippostrongylus brasiliensis. PLoS Neglected Tropical Diseases, 8 (12),

Brown, James E (2014). Can restricting calories help you to live longer? Post Reproductive Health, 20 (1), pp. 16-18.

C

Chimonides, G.F, Behrendt, J.M., Chundoo, E., Bland, C., Hine, A.V., Devitt, A., Nagel, D.A. and Sutherland, A.J. (2014). Cellular uptake of ribonuclease A-functionalised core-shell silica microspheres. Journal of Materials Chemistry B, 2 (42), pp. 7307-7315.

Choudhury, K., Clark, J. and Griffiths, H.R. (2014). An almond-enriched diet increases plasma α-tocopherol and improves vascular function but does not affect oxidative stress markers or lipid levels. Free Radical Research, 48 (5), pp. 599-606.

Claudius, Ann-Katrin, Kankipati, Chandra S., Kilari, Rajagopal S., Hassan, Sadiya, Guest, Kerry, Russell, Steven T., Perry, Chris J., Stark, Lesley A. and Nicholl, Iain D. (2014). Identification of aspirin analogues that repress NF-κB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo. Oncology Reports, 32 (4), pp. 1670-1680.

Conway, C., McGarry, J.P. and McHugh, P.E. (2014). Modelling of Atherosclerotic Plaque for Use in a Computational Test-Bed for Stent Angioplasty. Annals of Biomedical Engineering, 42 (12), 2425–2439.

Cunningham, Adam F., Flores-Langarica, Adriana, Bobat, Saeeda, Medina, Carmen C.Dominguez, Cook, Charlotte N.L., Ross, Ewan A., Lopez-Macias, Constantino and Henderson, Ian R. (2014). B1b cells recognize protective antigens after natural infection and vaccination. Frontiers in Immunology, 5 ,

D

Davies, Benjamin M, Rikabi, Sarah, French, Anna, Pinedo-Villanueva, Rafael, Morrey, Mark E, Wartolowska, Karolina, Judge, Andrew, MacLaren, Robert E, Mathur, Anthony, Williams, David J, Wall, Ivan, Birchall, Martin, Reeve, Brock, Atala, Anthony, Barker, Richard W, Cui, Zhanfeng, Furniss, Dominic, Bure, Kim, Snyder, Evan Y, Karp, Jeffrey M, Price, Andrew, Carr, Andrew and Brindley, David A (2014). Quantitative assessment of barriers to the clinical development and adoption of cellular therapies:A pilot study. Journal of Tissue Engineering, 5 ,

Day, Rebecca E., Kitchen, Philip, Owen, David, Bland, Charlotte, Marshall, Lindsay, Conner, Alex C., Bill, Roslyn M. and Conner, Matthew T. (2014). Human aquaporins:regulators of transcellular water flow. BBA - General Subjects, 1840 (5), pp. 1492-1506.

Dias, Irundika H.K. and Griffiths, Helen R. (2014). Oxidative stress in diabetes - circulating advanced glycation end products, lipid oxidation and vascular disease. Annals of Clinical Biochemistry, 51 (2), pp. 125-127.

Dias, Irundika H.K., Mistry, Jayna, Fell, Shaun, Reis, Ana, Spickett, Corinne M., Polidori, Maria C, Lip, Greg Y.H. and Griffiths, Helen R. (2014). Oxidised LDL-lipids increase beta amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation. Free Radical Biology and Medicine, 75 , 48–59.

Dias, Irundika H.K., Polidori, Maria Cristina, Li, Li, Weber, Daniela, Stahl, Wilhelm, Nelles, Gereon, Grune, Tilman and Griffiths, Helen R. (2014). Plasma levels of HDL and carotenoids are lower in dementia patients with vascular comorbidities. Journal of Alzheimer's Disease, 40 (2), pp. 399-408.

Dilworth, Marvin (2014). Novel strategies to improve recombinant membrane protein production in yeast. PHD thesis, Aston University.

F

Fouqueray, Pascale, Pirags, Valdis, Diamant, Michaela, Schernthaner, Guntram, Lebovitz, Harold E., Inzucchi, Silvio E. and Bailey, Clifford J. (2014). The efficacy and safety of imeglimin as add-on therapy in patients with type 2 diabetes inadequately controlled with sitagliptin monotherapy. Diabetes Care, 37 (7), pp. 1924-1930.

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Gawthorpe, Stephanie, Brown, James E., Arif, Muhammad, Nightingale, Peter, Nevill, Alan and Carmichael, Amtul R. (2014). Heparanase and COX-2 expression as predictors of lymph node metastasis in large, high-grade breast tumors. Anticancer Research, 34 (6), pp. 2797-2800.

Griffiths, Helen R., Dias, Irundika, Willetts, Rachel S. and Devitt, Andrew (2014). Redox regulation of protein damage in plasma. Redox biology, 2 (1), pp. 430-435.

Gross, Stephane R., Sin, Connie G.T., Barraclough, Roger and Rudland, Philip S. (2014). Joining S100 proteins and migration:for better or for worse, in sickness and in health. Cellular and Molecular Life Sciences, 71 (9), pp. 1551-1579.

Gulati, Sonali, Jamshad, Mohammed, Knowles, Timothy J., Morrison, Kerrie A., Downing, Rebecca, Cant, Natasha, Collins, Richard, Koenderink, Jan B., Ford, Robert C., Overduin, Michael, Kerr, Ian D., Dafforn, Timothy R. and Rothnie, Alice J. (2014). Detergent-free purification of ABC (ATP-binding-cassette) transporters. Biochemical Journal, 461 (2), pp. 269-278.

Gurcha, SS, Usha, V, Cox, JA, Fütterer, K, Abrahams, KA, Bhatt, A, Alderwick, LJ, Reynolds, RC, Loman, NJ, Nataraj, V, Alemparte, C, Barros, D, Lloyd, AJ, Ballell, L, Hobrath, JV and Besra, GS (2014). Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. PLoS ONE, 9 (11),

H

Hall, S.D., Prokic, E.J., McAllister, C.J., Rönnqvist, K.C., Williams, A.C., Yamawaki, N., Witton, C., Woodhall, G.L. and Stanford, I.M. (2014). GABA-mediated changes in inter-hemispheric beta frequency activity in early-stage Parkinson's disease. Neuroscience, 281 , pp. 68-76.

Harris, Nicola J., Findlay, Heather E., Simms, John, Liu, Xia and Booth, Paula J. (2014). Relative domain folding and stability of a membrane transport protein. Journal of Molecular Biology, 426 (8), pp. 1812-1825.

Hawkins, Lois (2014). The role of apoptotic cell clearance in a high-lipid environment:links to ageing. PHD thesis, Aston University.

Hawkins, Lois, Alghareeb, Khaled, Nadella, Vinod, Chauhan, Parbata, Bland, Charlotte E. and Devitt, Andrew (2014). Physical and functional characterisation of apoptotic cell-derived extracellular vesicles. IN: British Society for Immunology (BSI) annual congress. UK, 2014-12-01 - 2014-12-04.

Hay, Debbie L., Harris, Paul W.R., Kowalczyk, Renata, Brimble, Margaret A., Rathbone, Dan L, Barwell, James, Conner, Alex C. and Poyner, David R. (2014). Structure-activity relationships of the N-terminus of calcitonin gene-related peptide:key roles of alanine-5 and threonine-6 in receptor activation. British Journal of Pharmacology, 171 (2), pp. 415-426.

Home, Philip, Riddle, Matthew, Cefalu, William T., Bailey, Clifford J., Bretzel, Reinhard G., del Prato, Stefano, Leroith, Derek, Schernthaner, Guntram, van Gaal, Luc and Raz, Itamar (2014). Insulin therapy in people with type 2 diabetes:opportunities and challenges? Diabetes Care, 37 (6), pp. 1499-1508.

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Jhita, Tracey, Petrou, Stavros, Gumber, Anil, Szczepura, Ala, Raymond, Neil T. and Bellary, Srikanth (2014). Ethnic differences in health related quality of life for patients with type 2 diabetes. Health and Quality of Life Outcomes, 12 ,

Jiwaji, Meesbah, Sandison, Mairi E., Reboud, Julien, Stevenson, Ross, Daly, Rónán, Barkess, Gráinne, Faulds, Karen, Kolch, Walter, Graham, Duncan, Girolami, Mark A., Cooper, Jonathan M. and Pitt, Andrew (2014). Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells. PLoS ONE, 9 (6),

Jogia, J., Kulatunga, U., Yates, G.P. and Wedawatta, G. (2014). Culture and the psychological impacts of natural disasters: Implications for disaster management and disaster mental health. Built and Human Environment Review, 7 (1), p. 1.

K

Khanim, F., Davies, N., Veliça, P., Hayden, R., Ride, J., Pararasa, C., Chong, M.G., Gunther, U., Veerapen, N., Winn, P., Farmer, R., Trivier, E., Rigoreau, L., Drayson, M. and Bunce, C. (2014). Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate. British Journal of Cancer, 110 (6), pp. 1506-1516.

L

Lacey, Michael G., Gooding-Williams, Gerard, Prokic, Emma Jg, Yamawaki, Naoki, Hall, Stephen D., Stanford, Ian M. and Woodhall, Gavin L. (2014). Spike firing and IPSPs in layer V pyramidal neurons during beta oscillations in rat primary motor cortex (M1) in vitro. PLoS ONE, 9 (1),

Law, Charlotte, Cerminara, Nadia L., Apps, Richard and Lumb, Bridget M. (2014). Spino-olivary projections in the rat are anatomically separate from postsynaptic dorsal column projections. Journal of Comparative Neurology, 522 (9), pp. 2179-2190.

Lee, Jonathan and Law, Charlotte (2014). Inhibition and enhancement of contextual fear memory destabilization. Frontiers in Behavioral Neuroscience, 8 ,

Liu, Wei, Kavaliauskas, Darius, Schrader, Jared M., Poruri, Kiran, Birkedal, Victoria, Goldman, Emanuel, Jakubowski, Hieronim, Mandecki, Wlodek, Uhlenbeck, Olke C., Knudsen, Charlotte R., Goldman, Yale E. and Cooperman, Barry S. (2014). Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formation. ACS Chemical Biology, 9 (10), pp. 2421-2431.

M

Maciel, Elisabete, Neves, Bruno M., Santinha, Deolinda, Reis, Ana, Domingues, Pedro, Cruz, M. Teresa, Pitt, Andrew R., Spickett, Corinne M. and Domingues, M. Rosário M. (2014). Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH. Archives of Biochemistry and Biophysics, 548 , 38–45.

Murdoch, Colin E., Chaubey, Sanjay, Zeng, Lingfang, Yu, Bin, Ivetic, Aleksander, Walker, Simon J., Vanhoutte, Davy, Heymans, Stephane, Grieve, David J., Cave, Alison C., Brewer, Alison C., Zhang, Min and Shah, Ajay M. (2014). Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through proinflammatory effects and endothelial-mesenchymal transition. Journal of the American College of Cardiology, 63 (24), pp. 2734-2741.

Murdoch, Colin E., Shuler, Michaela, Haeussler, Dagmar J.F., Kikuchi, Ryosuke, Bearelly, Priyanka, Han, Jingyan, Watanabe, Yosuke, Fuster, José J., Walsh, Kenneth, Ho, Ye-Shih, Bachschmid, Markus M., Cohen, Richard A. and Matsui, Reiko (2014). Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. Journal of Biological Chemistry, 289 (12), pp. 8633-8644.

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Nagel, David, Behrendt, Jonathan M., Chimonides, Gwen F., Torr, Elizabeth E., Devitt, Andrew, Sutherland, Andy J. and Hine, Anna V. (2014). Polymeric microspheres as protein transduction reagents. Molecular and Cellular Proteomics, 13 (6), pp. 1543-1551.

Nayeri, Unzila A., Buhimschi, Irina A., Laky, Christine A., Cross, Sarah N., Duzyj, Christina M., Ramma, Wenda, Sibai, Baha M., Funai, Edmund F., Ahmed, Asif and Buhimschi, Catalin S. (2014). Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia. Hypertension, Publis ,

P

Peake, Matthew A, Caley, Mathew, Giles, Peter J, Wall, Ivan, Enoch, Stuart, Davies, Lindsay C, Kipling, David, Thomas, David W and Stephens, Phil (2014). Identification of a transcriptional signature for the wound healing continuum. Wound Repair and Regeneration, 22 (3), pp. 399-405.

R

Rajasekaran, Vidya (2014). Tissue Transglutaminase (TG2) is a potential therapeutic target in the treatment of chemoresistant breast cancer. PHD thesis, Aston University.

Rana, Karan S., Arif, Muhammad, Hill, Eric J., Aldred, Sarah, Nagel, David A., Nevill, Alan, Randeva, Harpal S., Bailey, Clifford J., Bellary, Srikanth and Brown, James E. (2014). Plasma irisin levels predict telomere length in healthy adults. Age, 36 (2), pp. 995-1001.

Rana, Karan S., Griffiths, Helen R., Navas, Placido and Brown, James (2014). The interaction between metabolic disease and ageing. Global Journal of Obesity, Diabetes and Metabolic Syndrome, 1 (1),

Reynolds, Lisa A., Harcus, Yvonne, Smith, Katherine A., Webb, Lauren M., Hewitson, James P., Ross, Ewan A., Brown, Sheila, Uematsu, Satoshi, Akira, Shizuo, Gray, David, Gray, Mohini, MacDonald, Andrew S., Cunningham, Adam F. and Maizels, Rick M. (2014). MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite heligmosomoides polygyrus. Journal of Immunology, 193 (6), pp. 2984-2993.

Rezende Valim, Lays, Davies, Julia A., Tveen Jensen, Karina, Guo, Rui, Willison, Keith R., Spickett, Corinne M., Pitt, Andrew R. and Klug, David R. (2014). Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy. Journal of Physical Chemistry: Part B, 118 (45), pp. 12855-12864.

Robaszkiewicz, Agnieszka, Bartosz, Grzegorz, Pitt, Andrew R., Thakker, Alpesh, Armstrong, Richard A., Spickett, Corinne M. and Soszyński, Mirosław (2014). HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells. Archives of Biochemistry and Biophysics, 548 , pp. 1-10.

Rocha-Rego, V., Jogia, J., Marquand, A.F., Mourao-Miranda, J., Simmons, A. and Frangou, S. (2014). Examination of the predictive value of structural magnetic resonance scans in bipolar disorder:a pattern classification approach. Psychological Medicine, 44 (3), pp. 519-532.

Ross, Ewan A., Flores-Langarica, Adriana, Bobat, Saeeda, Coughlan, Ruth E., Marshall, Jennifer L., Hitchcock, Jessica R., Cook, Charlotte N., Carvalho-Gaspar, Manuela M., Mitchell, Andrea M., Clarke, Mary, Garcia, Paloma, Cobbold, Mark, Mitchell, Tim J., Henderson, Ian R., Jones, Nick D., Anderson, Graham, Buckley, Christopher D. and Cunningham, Adam F. (2014). Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function. European Journal of Immunology, 44 (8), pp. 2318-2330.

Routledge, Sarah J., Poyner, David R. and Bill, Roslyn M. (2014). Antifoams:the overlooked additive? Pharmaceutical Bioprocessing, 2 (2), pp. 103-106.

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Saad, Zaynab, Arif, Muhammad, Yassen, Nahi, Jasim, Hameed, Jelawe, Majed and Brown, James (2014). Novel expression of microRNAs in serum samples of Iraqi breast cancer women. American Journal of Biomedicine, 2 (5), pp. 567-574.

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Torrão, Rita C., Bennett, Stuart J., Brown, James E. and Griffiths, Helen R. (2014). Does metabolic reprogramming underpin age-associated changes in T cell phenotype and function? Free Radical Biology and Medicine, 71 , 26–35.

Traikov, Sofia, Stange, Christoph, Wassmer, Thomas, Paul-Gilloteaux, Perrine, Salamero, Jean, Raposo, Graça and Hoflack, Bernard (2014). Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis. PLoS ONE, 9 (11),

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Vítek, Libor, Gbelcová, Helena, Muchová, Lucie, Váňová, Kateřina, Zelenka, Jaroslav, Koníčková, Renata, Šuk, Jakub, Zadinova, Marie, Knejzlík, Zdeněk, Ahmad, Shakil, Fujisawa, Takeshi, Ahmed, Asif and Ruml, Tomáš (2014). Antiproliferative effects of carbon monoxide on pancreatic cancer. Digestive and liver disease, 46 (4), pp. 369-375.

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Wang, J., Zhao, W.X., He, Y. and Li, X. (2014). Infer user interests via link structure regularization. ACM Transactions on Intelligent Systems and Technology, 5 (2),

Watkins, Adam J. and Sinclair, Kevin D. (2014). Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice. AJP Heart and Circulatory physiology, 306 (10), H1444-H1452.

Watkins, H.A., Walker, C.S., Ly, K.N., Bailey, R.J., Barwell, J., Poyner, D.R. and Hay, D.L. (2014). Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor:implications for adrenomedullin and calcitonin gene-related peptide pharmacology. British Journal of Pharmacology, 171 (3), pp. 772-788.

Wells, Timothy J, Whitters, Deborah, Sevastsyanovich, Yanina R, Heath, Jennifer N, Pravin, John, Goodall, Margaret, Browning, Douglas F, O'Shea, Matthew K, Cranston, Amy, De Soyza, Anthony, Cunningham, Adam F, MacLennan, Calman A, Henderson, Ian R and Stockley, Robert A (2014). Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing. Journal of Experimental Medicine, 211 (9), pp. 1893-1904.

Wilkhu, Jitinder S., McNeil, Sarah E., Anderson, David E. and Perrie, Yvonne (2014). Consideration of the efficacy of non-ionic vesicles in the targeted delivery of oral vaccines. Drug delivery and translational research, 4 (3), pp. 233-245.

Wilkhu, Jitinder S., McNeil, Sarah E., Anderson, David E. and Perrie, Yvonne (2014). Consideration of the efficacy of non-ionic vesicles in the targeted delivery of oral vaccines. Drug Delivery and Translational Research, 4 (3), pp. 233-245.