Browse by Aston Author

Ademowo, Opeyemi Stella, Sharma, Praveen, Cockwell, Paul, Reis, Ana, Chapple, Iain L, Griffiths, Helen R and Dias, Irundika H K (2020). Distribution of plasma oxidised phosphatidylcholines in chronic kidney disease and periodontitis as a co-morbidity. Free Radical Biology and Medicine, 146 , pp. 130-138.

Rossin, D., Dias, I.h.k., Solej, M., Milic, I., Pitt, A.r., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H.r., Spickett, C.m., Poli, G. and Biasi, F. (2019). Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration. Free Radical Biology and Medicine, 136 , pp. 35-44.

Egea, Javier, Fabregat, Isabel, Frapart, Yves M., Ghezzi, Pietro, Görlach, Agnes, Kietzmann, Thomas, Kubaichuk, Kateryna, Knaus, Ulla G., Lopez, Manuela G., Olaso-Gonzalez, Gloria, Petry, Andreas, Schulz, Rainer, Vina, Jose, Winyard, Paul, Abbas, Kahina, Ademowo, Stella, Afonso, Catarina B., Andreadou, Ioanna, Antelmann, Haike, Antunes, Fernando, Aslan, Mutay, Bachschmid, Markus M., Barbosa, Rui M., Belousov, Vsevolod, Berndt, Carsten, Bernlohr, David, Bertrán, Esther, Bindoli, Alberto, Bottari, Serge P., Brito, Paula M., Carrara, Guia, Casas, Ana I., Chatzi, Afroditi, Chondrogianni, Niki, Conrad, Marcus, Cooke, Marcus S., Costa, João G., Cuadrado, Antonio, My-Chan Dang, Pham, De Smet, Barbara, Debelec–butuner, Bilge, Dias, Irundika, Dunn, Joe Dan, Edson, Amanda J., El Assar, Mariam, El-Benna, Jamel, Ferdinandy, Péter, Fernandes, Ana S., Fladmark, Kari E., Förstermann, Ulrich, Giniatullin, Rashid, Giricz, Zoltán, Görbe, Anikó, Griffiths, Helen, Hampl, Vaclav, Hanf, Alina, Herget, Jan, Hernansanz-Agustín, Pablo, Hillion, Melanie, Huang, Jinjing, Ilikay, Serap, Jansen-Dürr, Pidder, Jaquet, Vincent, Joles, Jaap A., Kalyanaraman, Balaraman, Kaminskyy, Danylo, Karbaschi, Mahsa, Kleanthous, Marina, Klotz, Lars-Oliver, Korac, Bato, Korkmaz, Kemal Sami, Koziel, Rafal, Kračun, Damir, Krause, Karl-Heinz, Křen, Vladimír, Krieg, Thomas, Laranjinha, João, Lazou, Antigone, Li, Huige, Martínez-Ruiz, Antonio, Matsui, Reiko, Mcbean, Gethin J., Meredith, Stuart P., Messens, Joris, Miguel, Verónica, Mikhed, Yuliya, Milisav, Irina, Milković, Lidija, Miranda-Vizuete, Antonio, Mojović, Milos, Monsalve, María, Mouthuy, Pierre-Alexis, Mulvey, John, Münzel, Thomas, Muzykantov, Vladimir, Nguyen, Isabel T.N., Oelze, Matthias, Oliveira, Nuno G., Palmeira, Carlos M., Papaevgeniou, Nikoletta, Pavićević, Aleksandra, Pedre, Brandán, Peyrot, Fabienne, Phylactides, Marios, Pircalabioru, Gratiela G., Pitt, Andrew R., Poulsen, Henrik E., Prieto, Ignacio, Rigobello, Maria Pia, Robledinos-Antón, Natalia, Rodríguez-mañas, Leocadio, Rolo, Anabela P., Rousset, Francis, Ruskovska, Tatjana, Saraiva, Nuno, Sasson, Shlomo, Schröder, Katrin, Semen, Khrystyna, Seredenina, Tamara, Shakirzyanova, Anastasia, Smith, Geoffrey L., Soldati, Thierry, Sousa, Bebiana C., Spickett, Corinne M., Stancic, Ana, Stasia, Marie José, Steinbrenner, Holger, Stepanić, Višnja, Steven, Sebastian, Tokatlidis, Kostas, Tuncay, Erkan, Turan, Belma, Ursini, Fulvio, Vacek, Jan, Vajnerova, Olga, Valentová, Kateřina, van Breusegem, Frank, Varisli, Lokman, Veal, Elizabeth A., Yalçın, A. Suha, Yelisyeyeva, Olha, Žarković, Neven, Zatloukalová, Martina, Zielonka, Jacek, Touyz, Rhian M., Papapetropoulos, Andreas, Grune, Tilman, Lamas, Santiago, Schmidt, Harald H.H.W., di Lisa, Fabio and Daiber, Andreas (2017). European contribution to the study of ROS:a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS). Redox biology, 13 , pp. 94-162.

Griffiths, Helen R., Gao, Dan and Pararasa, Chathyan (2017). Redox regulation in metabolic programming and inflammation. Redox biology, 12 , pp. 50-57.

Refaat, Alaa, Pararasa, Chathyan, Arif, Muhammad, Brown, James E.P., Carmichael, Amtul, Ali, Sameh S., Sakurai, Hiroaki and Griffiths, Helen R. (2017). Bardoxolone-methyl inhibits migration and metabolism in MCF7 cells. Free Radical Research, 51 (2), pp. 211-221.

Perrie, Yvonne, Crofts, Fraser, Devitt, Andrew, Griffiths, Helen R, Kastner, Elisabeth and Nadella, Vinod (2016). Designing liposomal adjuvants for the next generation of vaccines. Advanced Drug Delivery Reviews, 99 (Part A), pp. 85-96.

Pararasa, Chathyan, Ikwuobe, John, Shigdar, Shahjahan, Boukouvalas, Alexis, Nabney, Ian T., Brown, James E., Devitt, Andrew, Bailey, Clifford J., Bennett, Stuart J. and Griffiths, Helen R. (2016). Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ. Aging Cell, 15 (1), pp. 128-139.

Dias, Irundika H.K., Brown, Caroline L.R., Polidori-Nelles, Maria Cristina, Lip, Gregory Y.H. and Griffiths, Helen R. (2015). LDL-Lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells:mitigation by statin intervention. Clinical Science, 129 (12), pp. 1195-1206.

Bennett, Stuart J., Augustyniak, Edyta M., Dunston, Christopher R., Brown, Richard A., Shantsila, Eduard, Lip, Gregory Y.H., Torrão, Rita D.C., Pararasa, Chathyan, Hussein, Ali R., Ladouce, Romain, Friguet, Bertrand and Griffiths, Helen R. (2015). CD4+ T cell surface alpha enolase is lower in older adults. Mechanisms of Ageing and Development, 152 , 56–62.

Bürkle, Alexander, Moreno-Villanueva, María, Bernhard, Jürgen, Blasco, María, Zondag, Gerben, Hoeijmakers, Jan H.J., Toussaint, Olivier, Grubeck-Loebenstein, Beatrix, Mocchegiani, Eugenio, Collino, Sebastiano, Gonos, Efstathios S., Sikora, Ewa, Gradinaru, Daniela, Dollé, Martijn, Salmon, Michel, Kristensen, Peter, Griffiths, Helen R., Libert, Claude, Grune, Tilman, Breusing, Nicolle, Simm, Andreas, Franceschi, Claudio, Capri, Miriam, Talbot, Duncan, Caiafa, Paola, Friguet, Bertrand, Slagboom, P. Eline, Hervonen, Antti, Hurme, Mikko and Aspinall, Richard (2015). MARK-AGE biomarkers of ageing. Mechanisms of Ageing and Development, 151 , pp. 2-12.

McBean, Gethin J., Aslan, Mutay, Griffiths, Helen R. and Torrão, Rita C (2015). Thiol redox homeostasis in neurodegenerative disease. Redox biology, 5 , pp. 186-194.

Augustyniak, Edyta, Adam, Aisha, Wojdyla, Katarzyna, Rogowska-Wrzesinska, Adelina, Willetts, Rachel, Korkmaz, Ayhan, Atalay, Mustafa, Weber, Daniela, Grune, Tilman, Borsa, Claudia, Gradinaru, Daniela, Chand Bollineni, Ravi, Fedorova, Maria and Griffiths, Helen (2015). Validation of protein carbonyl measurement:a multi-centre study. Redox biology, 4 , 149–157.

Ruskovska, Tatjana, Bennett, Stuart J., Brown, Caroline R., Dimitrov, Slave, Kamcev, Nikola and Griffiths, Helen R. (2015). Ankyrin is the major oxidised protein in erythrocyte membranes from end-stage renal disease patients on chronic haemodialysis and oxidation is decreased by dialysis and vitamin C supplementation. Free Radical Research, 49 (2), pp. 175-185.

Pararasa, Chathyan, Bailey, Clifford J. and Griffiths, Helen R. (2015). Ageing, adipose tissue, fatty acids and inflammation. Biogerontology, 16 (2), pp. 235-248.

Marshall, Lindsay J., Oguejiofor, Wilson, Willetts, Rachel S., Griffiths, Helen R. and Devitt, Andrew (2015). Developing accurate models of the human airways. Journal of Pharmacy and Pharmacology, 67 (3), pp. 464-472.

Taylor, Simon, Lam, Matthew, Pararasa, Chathyan, Brown, James E.P., Carmichael, Amtul R. and Griffiths, Helen R. (2015). Evaluating the evidence for targeting FOXO3a in breast cancer:a systematic review. Cancer Cell International, 15 (1),

Dunston, Christopher R., Herbert, Rebecca and Griffiths, Helen R. (2015). Improving T cell-induced response to subunit vaccines:opportunities for a proteomic systems approach. Journal of Pharmacy and Pharmacology, 67 (3), pp. 290-299.

Griffiths, H.R., Augustyniak, E.M., Bennett, S.J., Debacq-Chainiaux, F., Dunston, C.R., Kristensen, P., Melchjorsen, C.J., Navarrete, Santos A., Simm, A. and Toussaint, O. (2015). Novel ageing-biomarker discovery using data-intensive technologies. Mechanisms of Ageing and Development, 151 , pp. 114-121.

Dias, Irundika H.K., Mistry, Jayna, Fell, Shaun, Reis, Ana, Spickett, Corinne M., Polidori, Maria C, Lip, Greg Y.H. and Griffiths, Helen R. (2014). Oxidised LDL-lipids increase beta amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation. Free Radical Biology and Medicine, 75 , 48–59.

Rana, Karan S., Griffiths, Helen R., Navas, Placido and Brown, James (2014). The interaction between metabolic disease and ageing. Global Journal of Obesity, Diabetes and Metabolic Syndrome, 1 (1),

Dias, Irundika H.K., Polidori, Maria C. and Griffiths, Helen R. (2014). Hypercholesterolaemia-induced oxidative stress at the blood-brain barrier. Biochemical Society Transactions, 42 (4), pp. 1001-1005.

Torrão, Rita C., Bennett, Stuart J., Brown, James E. and Griffiths, Helen R. (2014). Does metabolic reprogramming underpin age-associated changes in T cell phenotype and function? Free Radical Biology and Medicine, 71 , 26–35.

Choudhury, K., Clark, J. and Griffiths, H.R. (2014). An almond-enriched diet increases plasma α-tocopherol and improves vascular function but does not affect oxidative stress markers or lipid levels. Free Radical Research, 48 (5), pp. 599-606.

Dias, Irundika H.K., Polidori, Maria Cristina, Li, Li, Weber, Daniela, Stahl, Wilhelm, Nelles, Gereon, Grune, Tilman and Griffiths, Helen R. (2014). Plasma levels of HDL and carotenoids are lower in dementia patients with vascular comorbidities. Journal of Alzheimer's Disease, 40 (2), pp. 399-408.

Dias, Irundika H.K. and Griffiths, Helen R. (2014). Oxidative stress in diabetes - circulating advanced glycation end products, lipid oxidation and vascular disease. Annals of Clinical Biochemistry, 51 (2), pp. 125-127.

Griffiths, Helen R., Dias, Irundika, Willetts, Rachel S. and Devitt, Andrew (2014). Redox regulation of protein damage in plasma. Redox biology, 2 (1), pp. 430-435.

Rogowska-Wrzesinska, A., Wojdyla, K., Nedić, O., Baron, C.P. and Griffiths, H.R. (2014). Analysis of protein carbonylation - pitfalls and promise in commonly used methods. Free Radical Research, 48 (10), pp. 1145-1162.

Russell, Wendy R., Baka, Athanasia, Björck, Inger, Delzenne, Nathalie, Gao, Dan, Griffiths, Helen R., Hadjilucas, Ellie, Juvonen, Kristiina, Lahtinen, Sampo, Lansink, Mirian, van Loon, Luc, Mykkänen, Hannu, Riccardi, Gabriele, Östman, Elin, Vinoy, Sophie and Weickert, Martin O. (2013). Impact of diet composition on blood glucose regulation. Critical Reviews in Food Science and Nutrition, 56 (4), pp. 541-590.

Turner, James E., Bennett, Stuart J., Campbell, John P., Bosch, Jos A., Aldred, Sarah and Griffiths, Helen R. (2013). The antioxidant enzyme peroxiredoxin-2 is depleted in lymphocytes seven days after ultra-endurance exercise. Free Radical Research, 47 (10), pp. 821-828.

Carilho Torrão, Rita B.D., Dias, Irundika H.K., Bennett, Stuart J., Dunston, Christopher R and Griffiths, Helen R. (2013). Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion. Chemistry Central Journal, 7 (1),

Dias, Irundika H.K., Chapple, Ian L.C., Milward, Mike, Grant, Melissa M., Hill, Eric, Brown, James and Griffiths, Helen R. (2013). Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro. PLoS ONE, 8 (6),

Weber, Daniela, Milkovic, Lidija, Bennett, Stuart J., Griffiths, Helen R., Zarkovic, Neven and Grune, Tilman (2013). Measurement of HNE-protein adducts in human plasma and serum by ELISA-Comparison of two primary antibodies. Redox biology, 1 (1), pp. 226-233.

Kolamunne, Rajitha T., Dias, Irundika H.K., Vernallis, Ann B., Grant, Melissa M. and Griffiths, Helen R. (2013). Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species. Redox biology, 1 (1), pp. 418-426.

Lam, Matthew, Carmichael, Amtul and Griffiths, Helen (2012). An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression. PLoS ONE, 7 (6),

Torr, E.E., Gardner, D.H., Thomas, L., Goodall, D.M., Bielemeier, A., Willetts, R., Griffiths, H.R., Marshall, L.J. and Devitt, A. (2012). Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells. Cell Death and Differentiation, 19 (4), pp. 671-679.

Wu, Zhangming, Choudhury, Khujesta, Griffiths, Helen R, Xu, Jinwu and Ma, Xianghong (2012). A novel silicon membrane-based biosensing platform using distributive sensing strategy and artificial neural networks for feature analysis. Biomedical Microdevices, 14 (1), pp. 83-93.

Qin, Lu, Bartlett, Hannah E., Griffiths, Helen R., Eperjesi, Frank, Armstrong, Richard A. and Gherghel, Doina (2011). Macular pigment optical density is related to blood glutathione levels in healthy individuals. Investigative Ophthalmology and Visual Science, 52 (9), pp. 5029-5033.

Dunston, Christopher and Griffiths, Helen R. (2010). The effect of ageing on macrophage Toll-like receptor-mediated responses in the fight against pathogens. Clinical and Experimental Immunology, 161 (3), pp. 407-416.

Polidori, M. Cristina, Pientka, Ludger, Nelles, Gereon and Griffiths, Helen R. (2010). Modulation of cholesterol in midlife affords cognitive advantage during ageing - a role for altered redox balance. International Journal of Clinical and Experimental Medicine, 3 (2), pp. 103-109.

Grant, Melissa M., Creese, Andrew J., Barr, Gordon, Ling, Martin R., Scott, Ann E., Matthews, John B., Griffiths, Helen R, Cooper, Helen J. and Chapple, Iain L.C. (2010). Proteomic analysis of a noninvasive human model of acute inflammation and its resolution:the twenty-one day gingivitis model. Journal of Proteome Research, 9 (9), pp. 4732-4744.

Griffiths, Helen R., Willetts, Rachel S., Grant, Melissa M., Mistry, Nalini, Lunec, Joseph and Bevan, Ruth J. (2009). In vivo vitamin C supplementation increases phosphoinositol transfer protein expression in peripheral blood mononuclear cells from healthy individuals. British Journal of Nutrition, 101 (10), pp. 1432-1439.

Toms, Tracey E., Panoulas, Vasileios F., Douglas, Karen M.J., Griffiths, Helen R and Kitas, George D. (2008). Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis:a cross-sectional study. Arthritis Research and Therapy, 10 (6),

Griffiths, Helen R. (2008). Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease? Autoimmunity Reviews, 7 (7), pp. 544-549.

Dias, Irundika H.K., Marshall, Lindsay, Lambert, Peter A., Chapple, Iain L.C., Matthews, John B. and Griffiths, Helen R. (2008). Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant. Infection and Immunity, 76 (1), pp. 317-323.

Griffiths, Helen R. and Grant, Melissa M. (2006). The use of proteomic techniques to explore the holistic effects of nutrients in vivo. Nutrition Research Reviews, 19 (2), pp. 284-293.

Taiwo, F. A., Powers, H. J., Nakano, E., Griffiths, Helen R. and Nugent, D. F. (2006). Free radical reactions in atherosclerosis; An EPR spectrometry study. Spectroscopy, 20 (2), pp. 67-80.

Nakano, E., Taiwo, F.A., Nugent, D., Griffiths, Helen R., Aldred, S., Paisi, M., Kwok, M., Bhatt, P., Hill, M.H.E, Moat, S. and Powers, H.J. (2005). Downstream effects on human low density lipoprotein of homocysteine exported from endothelial cells in an in vitro system. Journal of Lipid Research, 46 (3), pp. 484-493.

Gherghel, Doina, Griffiths, Helen R., Hilton, Emma J., Cunliffe, Ian A. and Hosking, Sarah L. (2005). Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma. Investigative Ophthalmology and Visual Science, 46 (3), pp. 877-883.

Grant, Melissa M., Barber, Vicki S. and Griffiths, Helen R. (2005). The presence of ascorbate induces expression of brain derived neurotrophic factor in SH-SY5Y neuroblastoma cells after peroxide insult, which is associated with increased survival. Proteomics, 5 (2), pp. 534-540.

Polidori, M. Cristina, Mattioli, Paola, Aldred, Sarah, Cecchetti, Roberta, Stahl, Wilhelm, Griffiths, Helen, Senin, Umberto, Sies, Helmut and Mecocci, Patrizia (2004). Plasma antioxidant status, immunoglobulin G oxidation and lipid peroxidation in demented patients:Relevance to Alzheimer disease and vascular dementia. Dementia and Geriatric Cognitive Disorders, 18 (3-4), pp. 265-270.

Phillips, Darren C. and Griffiths, Helen R. (2003). Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells. Biochemical Journal, 375 (Part 3), pp. 567-579.

Barber, Vicki S. and Griffiths, Helen R. (2003). Is glutathione an important neuroprotective effector molecule against amyloid beta toxicity? Biofactors, 17 (1-4), pp. 215-228.

Griffiths, Helen R. (2000). Antioxidants and protein oxidation. Free Radical Research, 33 (Supple), S47-S58.