Browse by Aston Author

Sanchez-aranguren, Lissette Carolina, Rezai, Homira, Ahmad, Shakil, Alzahrani, Faisal A., Sparatore, Anna, Wang, Keqing and Ahmed, Asif (2020). MZe786 Rescues Cardiac Mitochondrial Activity in High sFlt-1 and Low HO-1 Environment. Antioxidants, 9 (7), pp. 1-16.

Ahmed, Asif, Williams, David, Cheed, Versha, Middleton, Lee J, Ahmad, Shakil, Wang, Keqing, Vince, Alex T, Hewett, Peter, Spencer, Kevin, Khan, Khalid S, Daniels, Jane P, Barber, Katherine, Kilby, Mark, Knox, Ellen, Sellman, Tara, Trinham, Paula, Tuffnell, Derek, Jones, Vicky, Syson, Jennifer, Shah, Neil, Deeks, Laurie, Carter, Wendy, Dorman, Ed, Thomas, Susannah, Harrington, Deborah, Higgins, Nicola, Wilmott‐powell, Mirriam, Simpson, Nigel, Dolby, Vivian, Bricker, Leanne, Walkinshaw, Steve, Houghton, Gillian, Longworth, Heather, Williamson, Catherine, Dhanjal, Mandish, Noori, Muna, Machirori, Mavis, Howard, Richard, Murray, Rebecca, Weist, Sarah, Denison, Fiona, Crawford, Isobel, Robson, Stephen, Allan, Carly, Myers, Jenny, Bernatavicius, Giovanna, Moorhead, Lynsey, Chappell, Lucy, Nelson‐piercy, Catherine, Williams, David, Daley, Rebecca, Rosas, Miguel, Greer, Ian, Vitek, Libor, Shennan, Andy, Marlow, Neil, Marie Barnard, Ann, Thornton, Jim, Rennie, Janet, Peacock, Janet, Gao Smith, Fang, Hyde, Carolyn, Crawford, Isobel, Cudmore, Melissa, Furmston, Alex, Fulcher, Leanne, Homer, Leanne, Howman, Andrew, Hilken, Nicholas and Brown, Stephen (2020). Pravastatin for early-onset pre-eclampsia:a randomised, blinded, placebo-controlled trial. BJOG, 127 (4), pp. 478-488.

Gao, Xuefei, Nowak-imialek, Monika, Chen, Xi, Chen, Dongsheng, Herrmann, Doris, Ruan, Degong, Chen, Andy Chun Hang, Eckersley-maslin, Melanie A., Ahmad, Shakil, Lee, Yin Lau, Kobayashi, Toshihiro, Ryan, David, Zhong, Jixing, Zhu, Jiacheng, Wu, Jian, Lan, Guocheng, Petkov, Stoyan, Yang, Jian, Antunes, Liliana, Campos, Lia S., Fu, Beiyuan, Wang, Shengpeng, Yong, Yu, Wang, Xiaomin, Xue, Song-guo, Ge, Liangpeng, Liu, Zuohua, Huang, Yong, Nie, Tao, Li, Peng, Wu, Donghai, Pei, Duanqing, Zhang, Yi, Lu, Liming, Yang, Fengtang, Kimber, Susan J., Reik, Wolf, Zou, Xiangang, Shang, Zhouchun, Lai, Liangxue, Surani, Azim, Tam, Patrick P. L., Ahmed, Asif, Yeung, William Shu Biu, Teichmann, Sarah A., Niemann, Heiner and Liu, Pentao (2019). Establishment of porcine and human expanded potential stem cells. Nature Cell Biology, 21 (6), pp. 687-699.

Leyva, Francisco, Zegard, Abbasin, Okafor, Osita, De Bono, Joseph, Mcnulty, David, Ahmed, Asif, Marshall, Howard, Ray, Daniel and Qiu, Tian (2019). Survival after cardiac resynchronization therapy: results from 50 084 implantations. Europace, 21 (5), 754–762.

Agarwal, Swati, Alzahrani, Faisal and Ahmed, Asif (2018). Hormone Replacement Therapy: Would it be Possible to Replicate a Functional Ovary? International Journal of Molecular Sciences, 19 (10),

Sanchez Aranguren, Lissette and Ahmed, Asif (2018). Breakfast and subclinical atherosclerosis: a novel association that highlights the importance of dietary habits in the prevention of atherosclerotic diseases. Annals of Research Hospitals, 2018 , pp. 1-3.

Sanchez Aranguren, Lissette, Espinosa-González, Cindy T., González-Ortiz, Laura M., Sanabria-Barrera, Sandra M., Riaño-Medina, Carlos E., Nuñez, Andrés F., Ahmed, Asif, Vasquez-Vivar, Jeannette and López, Marcos (2018). Soluble Fms-like tyrosine kinase-1 alters cellular metabolism and mitochondrial bioenergetics in preeclampsia. Frontiers in Physiology, 9 ,

Guo, Dongqing, Murdoch, Colin E., Xu, Hao, Shi, Hui, Duan, Dayue Darrel, Ahmed, Asif and Gu, Yuchun (2017). Vascular endothelial growth factor signaling requires glycine to promote angiogenesis. Scientific Reports, 7 (1), p. 14749.

Fujisawa, Takeshi, Wang, Keqing, Niu, Xi-Lin, Egginton, Stuart, Ahmad, Shakil, Hewett, Peter W., Kontos, Christopher D. and Ahmed, Asif (2017). Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes. Cardiovascular Research, 113 (1), pp. 81-89.

Jaworski, Felipe M., Gentilini, Lucas D., Gueron, Geraldine, Meiss, Roberto P., Ortiz, Emiliano G., Berguer, Paula M., Ahmed, Asif, Navone, Nora, Rabinovich, Gabriel A., Compagno, Daniel, Laderach, Diego J. and Vazquez, Elba S. (2017). In vivo hemin conditioning targets the vascular and immunologic compartments and restrains prostate tumor development. Clinical Cancer Research, 23 (17), pp. 5135-5148.

Cai, Meng, Kolluru, Gopi K. and Ahmed, Asif (2017). Small molecule, big prospects:MicroRNA in pregnancy and its complications. Journal of Pregnancy, 2017 ,

Thangaratinam, Shakila, Allotey, John, Marlin, Nadine, Mol, Ben W., von Dadelszen, Peter, Ganzevoort, Wessel, Akkermans, Joost, Ahmed, Asif, Daniels, Jane, Deeks, Jon, Ismail, Khaled, Barnard, Ann Marie, Dodds, Julie, Kerry, Sally, Moons, Carl, Riley, Richard D. and Khan, Khalid S. (2017). Development and validation of Prediction models for Risks of complications in Early-onset Pre-eclampsia (PREP):a prospective cohort study. Health Technology Assessment, 21 (18),

Gu, Junzhong, Zhang, Huiyuan, Ji, Bingyang, Jiang, Hui, Zhao, Tao, Jiang, Rongcai, Zhang, Zhiren, Tan, Shengjiang, Ahmed, Asif and Gu, Yuchun (2017). Vesicle miR-195 derived from endothelial cells inhibits expression of serotonin transporter in vessel smooth muscle cells. Scientific Reports, 7 ,

Cai, Meng, Wang, Keqing, Murdoch, Colin E., Gu, Yuchun and Ahmed, Asif (2017). Heterodimerisation between VEGFR-1 and VEGFR-2 and not the homodimers of VEGFR-1 inhibit VEGFR-2 activity. Vascular Pharmacology, 88 , pp. 11-20.

Yetik-Anacak, Gunay, Sevin, Gulnur, Ozzayim, Ozge, Dereli, Mehmet Vehbi and Ahmed, Asif (2016). Hydrogen sulfide:a novel mechanism for the vascular protection by resveratrol under oxidative stress in mouse aorta. Vascular Pharmacology, In pre ,

Litvinova, Karina S., Ahmad, Shakil, Wang, Keqing, Rafailov, Ilya E., Sokolovski, Sergei G., Zhang, Lin, Rafailov, Edik U. and Ahmed, Asif (2016). A pilot study using laser-based technique for non-invasive diagnostics of hypertensive conditions in mice. Proceedings of SPIE - International Society for Optical Engineering, 9689 ,

Guo, Dongqing, Gu, Junzhong, Jiang, Hui, Ahmed, Asif, Zhang, Zhiren and Gu, Yuchun (2016). Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to the development of pulmonary arterial hypertension. Journal of Molecular and Cellular Cardiology, 91 , pp. 179-187.

Guo, Dongqing, Liang, Shenghui, Wang, Su, Tang, Chengchun, Yao, Bin, Wan, Wenhui, Zhang, Hailing, Jiang, Hui, Ahmed, Asif, Zhang, Zhiren and Gu, Yuchun (2016). Role of epithelial Na+ channels in endothelial function. Journal of Cell Science, 129 (2), pp. 290-297.

Ghosh, Chandra C., Thamm, Kristina, Berghelli, Anthony V., Schrimpf, Claudia, Maski, Manish R., Abid, Tanaz, Milam, Katelyn E., Rajakumar, Augustine, Santel, Ansgar, Kielstein, Jan T., Ahmed, Asif, Thickett, David, Wang, Keqin, Chase, Maureen, Donnino, Michael W., Aird, William C., Haller, Hermann, David, Sascha and Parikh, Samir M. (2015). Drug repurposing screen identifies Foxo1-dependent angiopoietin-2 regulation in sepsis. Critical Care Medicine, 43 (7), e230-e240.

Ahmed, Asif and Ramma, Wenda (2015). Unravelling the theories of pre-eclampsia:Are the protective pathways the new paradigm? British Journal of Pharmacology, 172 (6), pp. 1574-1586.

Vítek, Libor, Gbelcová, Helena, Muchová, Lucie, Váňová, Kateřina, Zelenka, Jaroslav, Koníčková, Renata, Šuk, Jakub, Zadinova, Marie, Knejzlík, Zdeněk, Ahmad, Shakil, Fujisawa, Takeshi, Ahmed, Asif and Ruml, Tomáš (2014). Antiproliferative effects of carbon monoxide on pancreatic cancer. Digestive and liver disease, 46 (4), pp. 369-375.

Ramma, Wenda and Ahmed, Asif (2014). Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia. Journal of Reproductive Immunology, 101-10 (1), pp. 153-160.

Nayeri, Unzila A., Buhimschi, Irina A., Laky, Christine A., Cross, Sarah N., Duzyj, Christina M., Ramma, Wenda, Sibai, Baha M., Funai, Edmund F., Ahmed, Asif and Buhimschi, Catalin S. (2014). Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia. Hypertension, Publis ,

Nayeri, Unzila A., Buhimschi, Irina A., Laky, Christine A., Cross, Sarah N., Duzyj, Christina M., Ramma, Wenda, Sibai, Baha M., Funai, Edmund F., Ahmed, Asif and Buhimschi, Catalin S. (2014). Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia. Hypertension, 63 (6), pp. 1285-1292.

Wegiel, Barbara, Gallo, David, Csizmadia, Eva, Harris, Clair, Belcher, John, Vercellotti, Gregory M., Penacho, Nuno, Seth, Pankaj, Sukhatme, Vikas, Ahmed, Asif, Pandolfi, Pier Paolo, Helczynski, Leszek, Bjartell, Anders, Persson, Jenny Liao and Otterbein, Leo E. (2013). Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth. Cancer Research, 73 (23), pp. 7009-7021.

Wang, Keqing, Ahmad, Shakil, Cai, Meng, Rennie, Jillian, Fujisawa, Takeshi, Crispi, Fatima, Baily, James, Miller, Mark R., Cudmore, Melissa, Hadoke, Patrick W.F., Wang, Rui, Gratacós, Eduard, Buhimschi, Irina A., Buhimschi, Catalin S. and Ahmed, Asif (2013). Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. Circulation, Early ,

Ramma, Wenda, Buhimschi, Irina A., Zhao, Guomao, Dulay, Antonette T., Nayeri, Unzila Ali, Buhimschi, Catalin S. and Ahmed, Asif (2012). The elevation in circulating anti-angiogenic factors is independent of markers of neutrophil activation in preeclampsia. Angiogenesis, 15 (3), pp. 333-340.

Cudmore, Melissa J., Hewett, Peter W., Ahmad, Shakil, Wang, Ke-Qing, Cai, Meng, Al-Ani, Bahjat, Fujisawa, Takeshi, Ma, Bin, Sissaoui, Samir, Ramma, Wenda, Miller, Mark R., Newby, David E., Gu, Yuchun, Barleon, Bernhard, Weich, Herbert and Ahmed, Asif (2012). The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis. Nature Communications, 3 ,

Cudmore, Melissa J., Ahmad, Shakil, Sissaoui, Samir, Ramma, Wenda, Ma, Bin, Fujisawa, Takeshi, Al-Ani, Bahjat, Wang, Keqing, Cai, Meng, Crispi, Fatima, Hewett, Peter W., Gratacós, Eduard, Egginton, Stuart and Ahmed, Asif (2012). Loss of Akt activity increases circulating soluble endoglin release in preeclampsia:identification of inter-dependency between Akt-1 and heme oxygenase-1. European Heart Journal, 33 (9), pp. 1150-1158.

Ramma, Wenda and Ahmed, Asif (2011). Is inflammation the cause of pre-eclampsia? Biochemical Society Transactions, 39 (6), pp. 1619-1627.

Ahmad, Shakil, Hewett, Peter W., Al-Ani, Bahjat, Sissaoui, Samir, Fujisawa, Takeshi, Cudmore, Melissa J. and Ahmed, Asif (2011). Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis. Vascular Cell, 3 (1),

Cai, Jun, Wu, Lin, Qi, Xiaoping, Shaw, Lynn, Li Calzi, Sergio, Caballero, Sergio, Jiang, Wen G., Vinores, Stanley A., Antonetti, David, Ahmed, Asif, Grant, Maria B. and Boulton, Michael E. (2011). Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability. PLoS ONE, 6 (3),

Bergmann, Astrid, Ahmad, Shakil, Cudmore, Melissa J., Gruber, Achim D., Wittschen, Petra, Lindenmaier, Werner, Christofori, Gerhard, Gross, Volkmar, Ch. da Costa Gonzalves, Andrey, Gröne, Hermann-Josef, Ahmed, Asif and Weich, Herbert A. (2010). Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. Journal of Cellular and Molecular Medicine, 14 (6b), pp. 1857-1867.

Wegiel, Barbara, Gallo, David J., Raman, Kathleen G., Karlsson, Jenny M., Ozanich, Brett, Chin, Beek Y., Tzeng, Edith, Ahmad, Shakil, Ahmed, Asif, Baty, Catherine J. and Otterbein, Leo E. (2010). Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. Circulation, 121 (4), pp. 537-548.

Ahmed, Asif, Fujisawa, Takeshi, Niu, Xi-Lin, Ahmad, Shakil, Al-Ani, Bahjat, Chudasama, Kunal, Abbas, Allyah, Potluri, Rahul, Bhandari, Vineet, Findley, Clarence M., Lam, Gregory K.W., Huang, Jianhua, Hewett, Peter W., Cudmore, Melissa J. and Kontos, Christopher D. (2009). Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide. Circulation Research, 104 (12), pp. 1333-1336.

Tintu, Andrei, Rouwet, Ellen, Verlohren, Stefan, Brinkmann, Joep, Ahmad, Shakil, Crispi, Fatima, van Bilsen, Marc, Carmeliet, Peter, Staff, Anne Cathrine, Tjwa, Marc, Cetin, Irene, Gratacos, Eduard, Hernandez-Andrade, Edgar, Hofstra, Leo, Jacobs, Michael, Lamers, Wouter H., Morano, Ingo, Safak, Erdal, Ahmed, Asif and le Noble, Ferdinand (2009). Hypoxia induces dilated cardiomyopathy in the chick embryo:mechanism, intervention, and long-term consequences. PLoS ONE, 4 (4),

Zhou, Cissy C., Ahmad, Shakil, Mi, Tiejuan, Abbasi, Shahrzad, Xia, Lingwei, Day, Mary-Clare, Ramin, Susan M., Ahmed, Asif, Kellems, Rodney E. and Xia, Yang (2008). Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling. Hypertension, 51 (4), pp. 1010-1019.

Zhou, Cissy Chenyi, Ahmad, Shakil, Mi, TieJuan, Xia, Lingwei, Abbasi, Shahrzad, Hewett, Peter W., Sun, ChunXiao, Ahmed, Asif, Kellems, Rodney E. and Xia, Yang (2007). Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy. Circulation Research, 100 (1), pp. 88-95.

Al-Ani, Bahjat, Hewett, Peter W., Ahmed, Suborna, Cudmore, Melissa, Fujisawa, Takeshi, Ahmad, Shakil and Ahmed, Asif (2006). The release of nitric oxide from S-nitrosothiols promotes angiogenesis. PLoS ONE, 1 (1),

Hewett, Peter W., Daft, Emma L., Laughton, Charles A., Ahmad, Shakil, Ahmed, Asif and Murray, J. Clifford (2006). Selective inhibition of the human tie-1 promoter with triplex-forming oligonucleotides targeted to ets binding sites. Molecular Medicine, 12 (1-3), pp. 8-16.

Dunk, Caroline and Ahmed, Asif (2001). Expression of VEGF-C and activation of its receptors VEGFR-2 and VEGFR-3 in trophoblast. Histology and Histopathology, 16 (2), pp. 359-375.

Ahmed, Asif, Rahman, Mahbubur, Zhang, Xian, Acevedo, Carmen H., Nijjar, Sarbjit, Rushton, Ian, Bussolati, Benedetta and St. John, Justin (2000). Induction of placental heme oxygenase-1 is protective against TNFα-induced cytotoxicity and promotes vessel relaxation. Molecular Medicine, 6 (5), pp. 391-409.

Somerset, David A., Li, Xiao-Feng, Afford, Simon, Strain, Alastair J., Ahmed, Asif, Sangha, Rajabant K., Whittle, Martin J. and Kilby, Mark D. (1998). Ontogeny of hepatocyte growth factor (HGF) and its receptor (c-met) in human placenta:reduced HGF expression in intrauterine growth restriction. American Journal of Pathology, 153 (4), pp. 1139-47.

Acevedo, Carmen H. and Ahmed, Asif (1998). Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy. Journal of Clinical Investigation, 101 (5), pp. 949-55.

Li, Xiao, Shams, Munjiba, Zhu, Jun, Khalig, Asud, Wilkes, Mark, Whittle, Martin, Barnes, Nicholas and Ahmed, Asif (1998). Cellular localization of AT1 receptor mRNA and protein in normal placenta and its reduced expression in intrauterine growth restriction. Angiotensin II stimulates the release of vasorelaxants. Journal of Clinical Investigation, 101 (2), pp. 442-54.