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Article

Dias, Heraliyawala K, Milic, Ivana, Lip, Gregory Y.H., Polidori, Maria Cristina, Devitt, Andrew and Griffiths, Helen R (2018). Simvastatin reduces circulating oxysterol levels in men with hypercholesterolemia. Redox biology ,

Rana, Karan S, Pararasa, Chathyan, Afzal, Islam, Nagel, David A, Hill, Eric J, Bailey, Clifford J, Griffiths, Helen R, Kyrou, Ioannis, Randeva, Harpal S, Bellary, Srikanth and Brown, James E (2017). Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels. Cardiovascular Diabetology, 16 (1),

Egea, Javier, Fabregat, Isabel, Frapart, Yves M., Ghezzi, Pietro, Görlach, Agnes, Kietzmann, Thomas, Kubaichuk, Kateryna, Knaus, Ulla G., Lopez, Manuela G., Olaso-Gonzalez, Gloria, Petry, Andreas, Schulz, Rainer, Vina, Jose, Winyard, Paul, Abbas, Kahina, Ademowo, Stella, Afonso, Catarina B., Andreadou, Ioanna, Antelmann, Haike, Antunes, Fernando, Aslan, Mutay, Bachschmid, Markus M., Barbosa, Rui M., Belousov, Vsevolod, Berndt, Carsten, Bernlohr, David, Bertrán, Esther, Bindoli, Alberto, Bottari, Serge P., Brito, Paula M., Carrara, Guia, Casas, Ana I., Chatzi, Afroditi, Chondrogianni, Niki, Conrad, Marcus, Cooke, Marcus S., Costa, João G., Cuadrado, Antonio, My-Chan Dang, Pham, De Smet, Barbara, Debelec–butuner, Bilge, Dias, Irundika, Dunn, Joe Dan, Edson, Amanda J., El Assar, Mariam, El-Benna, Jamel, Ferdinandy, Péter, Fernandes, Ana S., Fladmark, Kari E., Förstermann, Ulrich, Giniatullin, Rashid, Giricz, Zoltán, Görbe, Anikó, Griffiths, Helen, Hampl, Vaclav, Hanf, Alina, Herget, Jan, Hernansanz-Agustín, Pablo, Hillion, Melanie, Huang, Jinjing, Ilikay, Serap, Jansen-Dürr, Pidder, Jaquet, Vincent, Joles, Jaap A., Kalyanaraman, Balaraman, Kaminskyy, Danylo, Karbaschi, Mahsa, Kleanthous, Marina, Klotz, Lars-Oliver, Korac, Bato, Korkmaz, Kemal Sami, Koziel, Rafal, Kračun, Damir, Krause, Karl-Heinz, Křen, Vladimír, Krieg, Thomas, Laranjinha, João, Lazou, Antigone, Li, Huige, Martínez-Ruiz, Antonio, Matsui, Reiko, Mcbean, Gethin J., Meredith, Stuart P., Messens, Joris, Miguel, Verónica, Mikhed, Yuliya, Milisav, Irina, Milković, Lidija, Miranda-Vizuete, Antonio, Mojović, Milos, Monsalve, María, Mouthuy, Pierre-Alexis, Mulvey, John, Münzel, Thomas, Muzykantov, Vladimir, Nguyen, Isabel T.N., Oelze, Matthias, Oliveira, Nuno G., Palmeira, Carlos M., Papaevgeniou, Nikoletta, Pavićević, Aleksandra, Pedre, Brandán, Peyrot, Fabienne, Phylactides, Marios, Pircalabioru, Gratiela G., Pitt, Andrew R., Poulsen, Henrik E., Prieto, Ignacio, Rigobello, Maria Pia, Robledinos-Antón, Natalia, Rodríguez-mañas, Leocadio, Rolo, Anabela P., Rousset, Francis, Ruskovska, Tatjana, Saraiva, Nuno, Sasson, Shlomo, Schröder, Katrin, Semen, Khrystyna, Seredenina, Tamara, Shakirzyanova, Anastasia, Smith, Geoffrey L., Soldati, Thierry, Sousa, Bebiana C., Spickett, Corinne M., Stancic, Ana, Stasia, Marie José, Steinbrenner, Holger, Stepanić, Višnja, Steven, Sebastian, Tokatlidis, Kostas, Tuncay, Erkan, Turan, Belma, Ursini, Fulvio, Vacek, Jan, Vajnerova, Olga, Valentová, Kateřina, van Breusegem, Frank, Varisli, Lokman, Veal, Elizabeth A., Yalçın, A. Suha, Yelisyeyeva, Olha, Žarković, Neven, Zatloukalová, Martina, Zielonka, Jacek, Touyz, Rhian M., Papapetropoulos, Andreas, Grune, Tilman, Lamas, Santiago, Schmidt, Harald H.H.W., di Lisa, Fabio and Daiber, Andreas (2017). European contribution to the study of ROS:a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS). Redox biology, 13 , pp. 94-162.

Ademowo, O.S., Dias, H.K.I., Milic, I., Devitt, A., Moran, R., Mulcahy, R., Howard, A.N., Nolan, J.M. and Griffiths, H.R. (2017). Phospholipid oxidation and carotenoid supplementation in Alzheimer’s disease patients. Free Radical Biology and Medicine, 108 , pp. 77-85.

Perrie, Yvonne, Crofts, Fraser, Devitt, Andrew, Griffiths, Helen R, Kastner, Elisabeth and Nadella, Vinod (2016). Designing liposomal adjuvants for the next generation of vaccines. Advanced Drug Delivery Reviews, 99 (Part A), pp. 85-96.

Pararasa, Chathyan, Ikwuobe, John, Shigdar, Shahjahan, Boukouvalas, Alexis, Nabney, Ian T., Brown, James E., Devitt, Andrew, Bailey, Clifford J., Bennett, Stuart J. and Griffiths, Helen R. (2016). Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ. Aging Cell, 15 (1), pp. 128-139.

Russell, Wendy R., Baka, Athanasia, Björck, Inger, Delzenne, Nathalie, Gao, Dan, Griffiths, Helen R., Hadjilucas, Ellie, Juvonen, Kristiina, Lahtinen, Sampo, Lansink, Mirian, van Loon, Luc, Mykkänen, Hannu, Riccardi, Gabriele, Östman, Elin, Vinoy, Sophie and Weickert, Martin O. (2016). Impact of diet composition on blood glucose regulation. Critical Reviews in Food Science and Nutrition, 56 (4), pp. 541-590.

Dias, Irundika H.K., Brown, Caroline L.R., Polidori-Nelles, Maria Cristina, Lip, Gregory Y.H. and Griffiths, Helen R. (2015). LDL-Lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells:mitigation by statin intervention. Clinical Science, 129 (12), pp. 1195-1206.

Bennett, Stuart J., Augustyniak, Edyta M., Dunston, Christopher R., Brown, Richard A., Shantsila, Eduard, Lip, Gregory Y.H., Torrão, Rita D.C., Pararasa, Chathyan, Hussein, Ali R., Ladouce, Romain, Friguet, Bertrand and Griffiths, Helen R. (2015). CD4+ T cell surface alpha enolase is lower in older adults. Mechanisms of Ageing and Development, 152 , 56–62.

Bürkle, Alexander, Moreno-Villanueva, María, Bernhard, Jürgen, Blasco, María, Zondag, Gerben, Hoeijmakers, Jan H.J., Toussaint, Olivier, Grubeck-Loebenstein, Beatrix, Mocchegiani, Eugenio, Collino, Sebastiano, Gonos, Efstathios S., Sikora, Ewa, Gradinaru, Daniela, Dollé, Martijn, Salmon, Michel, Kristensen, Peter, Griffiths, Helen R., Libert, Claude, Grune, Tilman, Breusing, Nicolle, Simm, Andreas, Franceschi, Claudio, Capri, Miriam, Talbot, Duncan, Caiafa, Paola, Friguet, Bertrand, Slagboom, P. Eline, Hervonen, Antti, Hurme, Mikko and Aspinall, Richard (2015). MARK-AGE biomarkers of ageing. Mechanisms of Ageing and Development, 151 , pp. 2-12.

McBean, Gethin J., Aslan, Mutay, Griffiths, Helen R. and Torrão, Rita C (2015). Thiol redox homeostasis in neurodegenerative disease. Redox biology, 5 , pp. 186-194.

Augustyniak, Edyta, Adam, Aisha, Wojdyla, Katarzyna, Rogowska-Wrzesinska, Adelina, Willetts, Rachel, Korkmaz, Ayhan, Atalay, Mustafa, Weber, Daniela, Grune, Tilman, Borsa, Claudia, Gradinaru, Daniela, Chand Bollineni, Ravi, Fedorova, Maria and Griffiths, Helen (2015). Validation of protein carbonyl measurement:a multi-centre study. Redox biology, 4 , 149–157.

Ruskovska, Tatjana, Bennett, Stuart J., Brown, Caroline R., Dimitrov, Slave, Kamcev, Nikola and Griffiths, Helen R. (2015). Ankyrin is the major oxidised protein in erythrocyte membranes from end-stage renal disease patients on chronic haemodialysis and oxidation is decreased by dialysis and vitamin C supplementation. Free Radical Research, 49 (2), pp. 175-185.

Pararasa, Chathyan, Bailey, Clifford J. and Griffiths, Helen R. (2015). Ageing, adipose tissue, fatty acids and inflammation. Biogerontology, 16 (2), pp. 235-248.

Marshall, Lindsay J., Oguejiofor, Wilson, Willetts, Rachel S., Griffiths, Helen R. and Devitt, Andrew (2015). Developing accurate models of the human airways. Journal of Pharmacy and Pharmacology, 67 (3), pp. 464-472.

Taylor, Simon, Lam, Matthew, Pararasa, Chathyan, Brown, James E.P., Carmichael, Amtul R. and Griffiths, Helen R. (2015). Evaluating the evidence for targeting FOXO3a in breast cancer:a systematic review. Cancer Cell International, 15 (1),

Dunston, Christopher R., Herbert, Rebecca and Griffiths, Helen R. (2015). Improving T cell-induced response to subunit vaccines:opportunities for a proteomic systems approach. Journal of Pharmacy and Pharmacology, 67 (3), pp. 290-299.

Griffiths, H.R., Augustyniak, E.M., Bennett, S.J., Debacq-Chainiaux, F., Dunston, C.R., Kristensen, P., Melchjorsen, C.J., Navarrete, Santos A., Simm, A. and Toussaint, O. (2015). Novel ageing-biomarker discovery using data-intensive technologies. Mechanisms of Ageing and Development, 151 , pp. 114-121.

Dias, Irundika H.K., Mistry, Jayna, Fell, Shaun, Reis, Ana, Spickett, Corinne M., Polidori, Maria C, Lip, Greg Y.H. and Griffiths, Helen R. (2014). Oxidised LDL-lipids increase beta amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation. Free Radical Biology and Medicine, 75 , 48–59.

Rana, Karan S., Griffiths, Helen R., Brown, James E., Navas, Placido and Brown, James (2014). The interaction between metabolic disease and ageing. Global Journal of Obesity, Diabetes and Metabolic Syndrome, 1 (1),

Dias, Irundika H.K., Polidori, Maria C. and Griffiths, Helen R. (2014). Hypercholesterolaemia-induced oxidative stress at the blood-brain barrier. Biochemical Society Transactions, 42 (4), pp. 1001-1005.

Torrão, Rita C., Bennett, Stuart J., Brown, James E. and Griffiths, Helen R. (2014). Does metabolic reprogramming underpin age-associated changes in T cell phenotype and function? Free Radical Biology and Medicine, 71 , 26–35.

Choudhury, K., Clark, J. and Griffiths, H.R. (2014). An almond-enriched diet increases plasma α-tocopherol and improves vascular function but does not affect oxidative stress markers or lipid levels. Free Radical Research, 48 (5), pp. 599-606.

Dias, Irundika H.K. and Griffiths, Helen R. (2014). Oxidative stress in diabetes - circulating advanced glycation end products, lipid oxidation and vascular disease. Annals of Clinical Biochemistry, 51 (2), pp. 125-127.

Griffiths, Helen R., Dias, Irundika, Willetts, Rachel S. and Devitt, Andrew (2014). Redox regulation of protein damage in plasma. Redox biology, 2 (1), pp. 430-435.

Dias, Irundika H.K., Polidori, Maria Cristina, Li, Li, Weber, Daniela, Stahl, Wilhelm, Nelles, Gereon, Grune, Tilman and Griffiths, Helen R. (2014). Plasma levels of HDL and carotenoids are lower in dementia patients with vascular comorbidities. Journal of Alzheimer's disease, 40 (2), pp. 399-408.

Rogowska-Wrzesinska, A., Wojdyla, K., Nedić, O., Baron, C.P. and Griffiths, H.R. (2014). Analysis of protein carbonylation - pitfalls and promise in commonly used methods. Free Radical Research, 48 (10), pp. 1145-1162.

Turner, James E., Bennett, Stuart J., Campbell, John P., Bosch, Jos A., Aldred, Sarah and Griffiths, Helen R. (2013). The antioxidant enzyme peroxiredoxin-2 is depleted in lymphocytes seven days after ultra-endurance exercise. Free Radical Research, 47 (10), pp. 821-828.

Dias, Irundika H.K., Chapple, Ian L.C., Milward, Mike, Grant, Melissa M., Hill, Eric, Brown, James and Griffiths, Helen R. (2013). Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro. PLoS ONE, 8 (6),

Weber, Daniela, Milkovic, Lidija, Bennett, Stuart J., Griffiths, Helen R., Zarkovic, Neven and Grune, Tilman (2013). Measurement of HNE-protein adducts in human plasma and serum by ELISA-Comparison of two primary antibodies. Redox biology, 1 (1), pp. 226-233.

Kolamunne, Rajitha T., Dias, Irundika H.K., Vernallis, Ann B., Grant, Melissa M. and Griffiths, Helen R. (2013). Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species. Redox biology, 1 (1), pp. 418-426.

Gao, Dan, Pararasa, Chathyan, Dunston, Christopher R, Bailey, Clifford J. and Griffiths, Helen R. (2012). Palmitate promotes monocyte atherogenicity via de novo ceramide synthesis. Free Radical Biology and Medicine, 53 (4), 796–806.

Lam, Matthew, Carmichael, Amtul and Griffiths, Helen (2012). An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression. PLoS ONE, 7 (6),

Torr, E.E., Gardner, D.H., Thomas, L., Goodall, D.M., Bielemeier, A., Willetts, R., Griffiths, H.R., Marshall, L.J. and Devitt, A. (2012). Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells. Cell Death and Differentiation, 19 (4), pp. 671-679.

Wu, Zhangming, Choudhury, Khujesta, Griffiths, Helen R, Xu, Jinwu and Ma, Xianghong (2012). A novel silicon membrane-based biosensing platform using distributive sensing strategy and artificial neural networks for feature analysis. Biomedical Microdevices, 14 (1), pp. 83-93.

Qin, Lu, Bartlett, Hannah E., Griffiths, Helen R., Eperjesi, Frank, Armstrong, Richard A. and Gherghel, Doina (2011). Macular pigment optical density is related to blood glutathione levels in healthy individuals. Investigative Ophthalmology and Visual Science, 52 (9), pp. 5029-5033.

Dunston, Christopher and Griffiths, Helen R. (2010). The effect of ageing on macrophage Toll-like receptor-mediated responses in the fight against pathogens. Clinical and Experimental Immunology, 161 (3), pp. 407-416.

Polidori, M. Cristina, Pientka, Ludger, Nelles, Gereon and Griffiths, Helen R. (2010). Modulation of cholesterol in midlife affords cognitive advantage during ageing - a role for altered redox balance. International Journal of Clinical and Experimental Medicine, 3 (2), pp. 103-109.

Grant, Melissa M., Creese, Andrew J., Barr, Gordon, Ling, Martin R., Scott, Ann E., Matthews, John B., Griffiths, Helen R, Cooper, Helen J. and Chapple, Iain L.C. (2010). Proteomic analysis of a noninvasive human model of acute inflammation and its resolution:the twenty-one day gingivitis model. Journal of Proteome Research, 9 (9), pp. 4732-4744.

Griffiths, Helen R., Willetts, Rachel S., Grant, Melissa M., Mistry, Nalini, Lunec, Joseph and Bevan, Ruth J. (2009). In vivo vitamin C supplementation increases phosphoinositol transfer protein expression in peripheral blood mononuclear cells from healthy individuals. British Journal of Nutrition, 101 (10), pp. 1432-1439.

Toms, Tracey E., Panoulas, Vasileios F., Douglas, Karen M.J., Griffiths, Helen R and Kitas, George D. (2008). Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis:a cross-sectional study. Arthritis Research and Therapy, 10 (6),

Griffiths, Helen R. (2008). Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease? Autoimmunity Reviews, 7 (7), pp. 544-549.

Dias, Irundika H.K., Marshall, Lindsay, Lambert, Peter A., Chapple, Iain L.C., Matthews, John B. and Griffiths, Helen R. (2008). Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant. Infection and Immunity, 76 (1), pp. 317-323.

Grant, Melissa M., Scheel-Toellner, D. and Griffiths, Helen R. (2007). Contributions to our understanding of T cell physiology through unveiling the T cell proteome. Clinical and Experimental Immunology, 149 (1), pp. 9-15.

Griffiths, Helen R. and Grant, Melissa M. (2006). The use of proteomic techniques to explore the holistic effects of nutrients in vivo. Nutrition Research Reviews, 19 (2), pp. 284-293.

Woollard, Kevin J., Rayment, Sarah J., Bevan, Ruth, Shaw, Jacqui A., Lunec, Joseph and Griffiths, Helen R. (2006). α-Tocopherol supplementation does not affect monocyte endothelial adhesion or C-reactive protein levels but reduces soluble vascular adhesion molecule-1 in the plasma of healthy subjects. Redox report, 11 (5), pp. 214-222.

Luan, Yingjun and Griffiths, Helen R. (2006). Ceramides reduce CD36 cell surface expression and oxidised LDL uptake by monocytes and macrophages. Archives of Biochemistry and Biophysics, 450 (1), pp. 89-99.

Taiwo, F. A., Powers, H. J., Nakano, E., Griffiths, Helen R. and Nugent, D. F. (2006). Free radical reactions in atherosclerosis; An EPR spectrometry study. Spectroscopy, 20 (2), pp. 67-80.

Aldred, Sarah, Sozzi, Tommaso, Mudway, Ian, Grant, Melissa M., Neubert, Hendrik, Kelly, Frank J. and Griffiths, Helen R. (2006). Alpha tocopherol supplementation elevates plasma apolipoprotein A1 isoforms in normal healthy subjects. Proteomics, 6 (5), pp. 1695-1703.

Williamson, Matthew R., Woollard, Kevin J., Griffiths, Helen R. and Coombes, Allan G.A. (2006). Gravity spun polycaprolactone fibers for applications in vascular tissue engineering:proliferation and function of human vascular endothelial cells. Tissue Engineering, 12 (1), pp. 45-51.

Griffiths, Helen R., Aldred, Sarah, Dale, Chloe, Nakano, Emi, Kitas, George D., Grant, Melissa G., Nugent, Desmond, Taiwo, Fatai A., Li, Li and Powers, Hilary J. (2006). Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake. Free Radical Biology and Medicine, 40 (3), pp. 488-500.

Woollard, Kevin J., Fisch, C., Newby, R. and Griffiths, Helen R. (2005). C-reactive protein mediates CD11b expression in monocytes through the non-receptor tyrosine kinase, Syk, and calcium mobilization but not through cytosolic peroxides. Inflammation Research, 54 (12), pp. 485-492.

Griffiths, Helen R. (2005). ROS as signalling molecules in T cells - Evidence for abnormal redox signalling in the autoimmune disease, rheumatoid arthritis. Redox report, 10 (6), pp. 273-280.

Anlasik, Timur, Sies, Helmut, Griffiths, Helen R., Mecocci, Patrizia, Stahl, Wilhelm and Polidori, M. Cristina (2005). Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjects. British Journal of Nutrition, 94 (5), pp. 639-642.

Nakano, E., Taiwo, F.A., Nugent, D., Griffiths, Helen R., Aldred, S., Paisi, M., Kwok, M., Bhatt, P., Hill, M.H.E, Moat, S. and Powers, H.J. (2005). Downstream effects on human low density lipoprotein of homocysteine exported from endothelial cells in an in vitro system. Journal of Lipid Research, 46 (3), pp. 484-493.

Gherghel, Doina, Griffiths, Helen R., Hilton, Emma J., Cunliffe, Ian A. and Hosking, Sarah L. (2005). Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma. Investigative Ophthalmology and Visual Science, 46 (3), pp. 877-883.

Grant, Melissa M., Barber, Vicki S. and Griffiths, Helen R. (2005). The presence of ascorbate induces expression of brain derived neurotrophic factor in SH-SY5Y neuroblastoma cells after peroxide insult, which is associated with increased survival. Proteomics, 5 (2), pp. 534-540.

Phillips, D. C., Kitas, G. D. and Griffiths, Helen R. (2005). Altered redox signalling processes contribute to T-cell hyporesponsiveness. Free Radical Research, 39 (Suppl.), S17-S17.

Choudhury, Khujesta and Griffiths, Helen R. (2005). Enriching the diet of healthy subjects with almonds - Results from pilot study show reduced VCAM-1 shedding but increased protein oxidation. Free Radical Research, 39 (Suppl.), S53-S53.

Li, Li and Griffiths, Helen R. (2005). Homocysteine promotes post-translational modifications to HDL in a dose dependent manner. Free Radical Research, 39 (Suppl.), S66-S66.

Grant, M.M., Griffiths, Helen R. and Lunec, Joseph (2005). Modulation of the T-cell proteome by vitamin C. Free Radical Research, 39 (Suppl.), S40-S40.

Bevan, Ruth J., Durand, Mireille F., Griffiths, Helen R. and Lunec, Joseph (2005). Role of glyoxal mediated modifications of low density lipoprotein in diabetic atherosclerosis. Free Radical Research, 39 (Suppl.), S51-S51.

Luan, Y.J. and Griffiths, Helen R. (2005). Short chain ceramide reduces cytosolic peroxides by disrupting NADPH oxidase and inhibiting P47 association with lipid rafts. Free Radical Research, 39 (Suppl.), S67-S67.

Aldred, Sarah, Grant, Melissa M. and Griffiths, Helen R. (2004). The use of proteomics for the assessment of clinical samples in research. Clinical Biochemistry, 37 (11), pp. 943-952.

Polidori, M. Cristina, Mattioli, Paola, Aldred, Sarah, Cecchetti, Roberta, Stahl, Wilhelm, Griffiths, Helen, Senin, Umberto, Sies, Helmut and Mecocci, Patrizia (2004). Plasma antioxidant status, immunoglobulin G oxidation and lipid peroxidation in demented patients:Relevance to Alzheimer disease and vascular dementia. Dementia and Geriatric Cognitive Disorders, 18 (3-4), pp. 265-270.

Mecocci, Patrizia, Mattioli, Paola, Cecchetti, Roberta, Griffiths, Helen R., Aldred, Sarah, Stahl, Wilhelm and Polidori, Maria Cristina (2004). P4-235 protein oxidation, lipid peroxidation and antioxidant status are similarly altered in Alzheimer disease and vascular dementia. Neurobiology of Aging, 25 (supple), S542-S542.

Aldred, Sarah and Griffiths, Helen R. (2004). Oxidation of protein in human low-density lipoprotein exposed to peroxyl radicals facilitates uptake by monocytes; protection by antioxidants in vitro. Environmental Toxicology and Pharmacology, 15 (2-3), pp. 111-117.

Bevan, Ruth J., Durand, Mireille F., Hickenbotham, Peter T., Kitas, George D., Patel, Parul R., Podmore, Ian D., Griffiths, Helen R., Waller, Helen L. and Lunec, Joseph (2003). Validation of a novel ELISA for measurement of MDA-LDL in human plasma. Free Radical Biology and Medicine, 35 (5), pp. 517-527.

Cooke, Marcus S., Podmore, Ian D., Mistry, Nalini, Evans, Mark D., Herbert, Karl E., Griffiths, Helen R. and Lunec, Joseph (2003). Immunochemical detection of UV-induced DNA damage and repair. Journal of Immunological Methods, 280 (1-2), pp. 125-133.

Rayment, Sarah J., Shaw, Jacqui, Woollard, Kevin J., Lunec, Joe and Griffiths, Helen R. (2003). Vitamin C supplementation in normal subjects reduces constitutive ICAM-1 expression. Biochemical and Biophysical Research Communications, 308 (2), pp. 339-345.

Phillips, Darren C. and Griffiths, Helen R. (2003). Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells. Biochemical Journal, 375 (Part 3), pp. 567-579.

Mistry, Nalini, Podmore, Ian, Cooke, Marcus, Butler, Paul, Griffiths, Helen R., Herbert, Karl and Lunec, Joseph (2003). Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal. Laboratory Investigation, 83 (2), pp. 241-250.

Phillips, Darren C., Woollard, Kevin J. and Griffiths, Helen R. (2003). The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species. British Journal of Pharmacology, 138 (3), pp. 501-511.

Cooke, Marcus S., Mistry, Nalini, Ahmad, Jabeen, Waller, Helen, Langford, Lynda, Bevan, Ruth J., Evans, Mark D., Jones, George D.D., Herbert, Karl E., Griffiths, Helen R. and Lunec, Joseph (2003). Deoxycytidine glyoxal:Lesion induction and evidence of repair following vitamin C supplementation in vivo. Free Radical Biology and Medicine, 34 (2), pp. 218-225.

Lunec, Joseph, Holloway, Karen A., Griffiths, Helen R and Faux, S.P. (2003). Ascorbid acid induces an oxidative stress in CCRF cells activating the transcription factors AP-1 and NF kappa B. Free Radical Research, 37 (Suppl.), p. 117.

Woollard, Kevin J. and Griffiths, Helen R. (2003). C-Reactive protein signals through the non-receptor tyrosine kinase Syk and induces the expression of TNF-alpha and IL-6 in human monocytes. FASEB Journal, 17 (7), C70-C70.

An, E., Woollard, Kevin, Adams, Eric F. and Griffiths, Helen R. (2003). Evaluation of Fc gamma RIIa-H/R polymorphism by allele-specific primer polymerase chain reaction (PCR). FASEB Journal, 17 (7), C106-C106.

Barber, Vicki S. and Griffiths, Helen R. (2003). Is glutathione an important neuroprotective effector molecule against amyloid beta toxicity? Biofactors, 17 (1-4), pp. 215-228.

Luan, E., Phillips, D.C. and Griffiths, Helen R. (2003). Synthetic ceramides inhibit CD36 expression in U937 cells through a reduction in cytosolic peroxide. Free Radical Research, 37 (Suppl.), p. 40.

Woollard, Kevin J., Phillips, Darren C. and Griffiths, Helen R. (2002). Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells. Clinical and Experimental Immunology, 130 (2), pp. 256-262.

Lunec, Joseph, Holloway, Karen A., Cooke, Marcus S., Faux, Steve, Griffiths, Helen R. and Evans, Mark D. (2002). Urinary 8-oxo-2′-deoxyguanosine:Redox regulation of DNA repair in vivo? Free Radical Biology and Medicine, 33 (7), pp. 875-885.

Cooke, Marcus S., Evans, Mark D., Patel, K., Bogdanov, M., Mistry, Nalini, Holloway, Karen A., Griffiths, Helen R., Bevan, Ruth J., Durand, Mireille F. and Lunec, Joseph (2002). Repair of oxidative DNA damage: benefits of multiple lesion measurement. Free Radical Research, 36 (Suppl.), pp. 42-44.

Woollard, Kevin J., Loryman, Chris J., Meredith, Elizabeth, Bevan, Ruth J., Shaw, Jacqui A., Lunec, Joe and Griffiths, Helen R. (2002). Effects of oral vitamin C on monocyte:Endothelial cell adhesion in healthy subjects. Biochemical and Biophysical Research Communications, 294 (5), pp. 1161-1168.

Griffiths, Helen R. (2002). The influence of diet on protein oxidation. Nutrition Research Reviews, 15 (1), pp. 3-17.

Jackson, Malcolm J., Papa, Sergio, Bolaños, Juan, Bruckdorfer, Richard, Carlsen, Harald, Elliott, Ruan M, Flier, Jacoba, Griffiths, Helen R., Heales, Simon, Holst, Birgit, Lorusso, Michele, Lund, Elizabeth, Øivind Moskaug, Jan, Moser, Ulrich, Di Paola, Marco, Polidori, M Cristina, Signorile, Anna, Stahl, Wilhelm, Viña-Ribes, José and Astley, Siân B. (2002). Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function. Molecular Aspects of Medicine, 23 (1-3), pp. 209-285.

Rayment, Sarah J., Shaw, Jacqui A., Lunec, Joseph and Griffiths, Helen R. (2002). Dietary vitamin C supplementation, but not vitamin E, can modulate transcription of the redox sensitive gene, ICAM-1. Free Radical Research, 36 (Suppl.), pp. 57-58.

Woollard, Kevin J., Loryman, C.J., Meredith, E., Shaw, Jacqui A., Lunec, Joseph and Griffiths, Helen R. (2002). Effects of dietary vitamin C on monocyte adhesion to endothelial cells in healthy subjects with low plasma ascorbate. Free Radical Research, 36 (Suppl.), pp. 60-61.

Phillips, Darren Charles, Allen, Kirsty and Griffiths, Helen R. (2002). Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status. Archives of Biochemistry and Biophysics, 407 (1), pp. 15-24.

Griffiths, Helen R. (2000). Antioxidants and protein oxidation. Free Radical Research, 33 (Supple), S47-S58.

Carty, Julie L., Bevan, Ruth J., Waller, Helen, Mistry, Nalini, Cooke, Marcus S., Lunec, Joseph and Griffiths, Helen R. (2000). The effects of vitamin C supplementation on protein oxidation in healthy volunteers. Biochemical and Biophysical Research Communications, 273 (2), pp. 729-735.

Griffiths, Helen R., Wright, J., Bevan, Ruth J. and Lunec, Joseph (1999). Oxidative modification of a specific apolipoprotein B lysine residue confers altered receptor specificity on LDL. Redox report, 4 (6), pp. 337-339.

Mistry, Nalini, Evans, Mark D., Griffiths, Helen R., Kasai, H., Herbert, Karl E. and Lunec, Joseph (1999). Immunochemical detection of glyoxal DNA damage. Free Radical Biology and Medicine, 26 (9-10), pp. 1267-1273.

Cooke, Marcus S., Evans, Mark D., Podmore, Ian D., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha, Hickenbotham, Peter T., Hussieni, Amina, Griffiths, Helen R. and Lunec, Joseph (1998). Novel repair action of vitamin C upon in vivo oxidative DNA damage. FEBS Letters, 439 (3), pp. 363-367.

Griffiths, Helen R., Mistry, Pratibha, Herbert, Karl E. and Lunec, Joseph (1998). Molecular and cellular effects of ultraviolet light-induced genotoxicity. Critical Reviews in Clinical Laboratory Sciences, 35 (3), pp. 189-237.

Podmore, Ian D., Griffiths, Helen R., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha and Lunec, Joseph (1998). Vitamin C exhibits pro-oxidant properties. Nature, 392 (6676), p. 559.

Griffiths, Helen R. and Lunec, Joseph (1996). The C1q binding activity of IgG is modified in vitro by reactive oxygen species: implications for rheumatoid arthritis. FEBS Letters, 388 (2-3), pp. 161-164.

Finnegan, M.T., Herbert, Karl E., Evans, Mark D., Griffiths, Helen R. and Lunec, Joseph (1996). Evidence for sensitisation of DNA to oxidative damage during isolation. Free Radical Biology and Medicine, 20 (1), pp. 93-98.

Willets, J.M., Lambert, D.G., Lunec, Joseph and Griffiths, Helen R. (1995). Studies on the neurotoxicity of 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (salsolinol) in SH-SY5Y cells. European Journal of Pharmacology, 293 (4), pp. 319-326.

Mistry, Nalini, Herbert, Karl E., Evans, Mark D., Griffiths, Helen R. and Lunec, Joseph (1995). Immunochemical detection of reactive oxygen species DNA damage. Biochemical Society Transactions, 23 (3), 482S.

Hill, Colin M., Lunec, Joseph, Griffiths, Helen R. and Herbert, Karl E. (1995). Characterization of tumour necrosis factor alpha release by human granulocytes in response to procainamide challenge. Biochemical Pharmacology, 49 (12), pp. 1837-49.

Griffiths, Helen R. and Lunec, Joseph (1995). Agalactosylation by reactive oxygen species and Fc related changes to function. Advances in Experimental Medicine and Biology, 376 , pp. 161-170.

Herbert, Karl E., Mistry, Nalini, Griffiths, Helen R. and Lunec, Joseph (1994). Immunochemical detection of sequence-specific modifications to DNA induced by UV light. Carcinogenesis, 15 (11), pp. 2517-2521.

Lunec, Joseph, Herbert, Karl E., Blount, Susan, Griffiths, Helen R. and Emery, Paul (1994). 8-Hydroxydeoxyguanosine. A marker of oxidative DNA damage in systemic lupus erythematosus. FEBS Letters, 348 (2), pp. 131-138.

Willets, J.M., Lambert, D.G. and Griffiths, Helen R. (1993). Suitability of B65 and SH-SY5Y neuroblastoma cells as models for 'in vitro' neurotoxicity testing. Biochemical Society Transactions, 21 (4), 452S.

Willets, J.M., Lunec, Joseph, Williams, A.C. and Griffiths, Helen R. (1993). Neurotoxicity of nicotinamide derivatives: their role in the aetiology of Parkinson's disease. Biochemical Society Transactions, 21 (pt (3), 299S.

Blount, Susan, Griffiths, Helen R., Staines, N.A. and Lunec, Joseph (1992). Probing molecular changes induced in DNA by reactive oxygen species with monoclonal antibodies. Immunology Letters, 34 (2), pp. 115-126.

Griffiths, Helen R., Dowling, E.J., Sahinoglu, T., Blake, D, Parnham, M. and Lunec, Joseph (1992). The selective protection afforded by ebselen against lipid peroxidation in an ROS-dependent model of inflammation. Inflammation Research, 36 (1-2), pp. 107-111.

Griffiths, Helen R. and Lunec, Joseph (1991). Effects of reactive oxygen species on immunoglobulin G function. Molecular Aspects of Medicine, 12 (2), pp. 107-119.

Blount, Susan, Griffiths, Helen R. and Lunec, Joseph (1991). Reactive oxygen species damage to DNA and its role in systemic lupus erythematosus. Molecular Aspects of Medicine, 12 (2), pp. 93-105.

Lai, M. and Griffiths, Helen R. (1990). Role of reactive oxygen species in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Biochemical Society Transactions, 18 (3), pp. 416-417.

Blount, S., Griffiths, Helen R. and Lunec, Joseph (1989). Reactive oxygen species induce antigenic changes in DNA. FEBS Letters, 245 (1-2), pp. 100-104.

Griffiths, Helen R. and Lunec, Joseph (1989). The effects of oxygen free radicals on the carbohydrate moiety of IgG. FEBS Letters, 245 (1-2), pp. 95-99.

Griffiths, Helen R., Lunec, Joseph, Gee, C.A. and Willson, R.L. (1988). Oxygen radical induced alterations in polyclonal IgG. FEBS Letters, 230 (1-2), pp. 155-158.

Griffiths, Helen R. and Lunec, Joseph (1988). Effect of polymorph derived oxidants on IgG in relation to rheumatoid factor binding. Scandinavian Journal of Rheumatology, 17 (s75), pp. 148-156.

Conference or Workshop Item

Lunec, Joseph, Duarte, T., Holloway, Karen A., Griffiths, Helen R and Faux, S.P. (2004). Ascorbic acid induces an oxidative stress in CCRF cells activating the transcription factors AP-1 and NFRB. IN: 12th Biennial Meeting of the Society for free radical research. 2004-05-05 - 2004-05-09.

Griffiths, Helen R. and Woollard, Kevin (2003). C-reactive protein mediates CD11B expression in monocytes through the non-receptor tyrosine kinase, Syk, and not through cytosolic peroxides. IN: SFRBM's 10th Annual Meeting. 2003-11-01.

Grant, M. and Griffiths, Helen R. (2003). Detection of carbonylation and 3-nitrotyrosine as protein oxidation biomarkers. IN: Society of Toxicology Annual Conference. 2003-01-01 - 2003-01-01. (Unpublished)

Griffiths, Helen R., Rayment, Sarah, Shaw, Jaqui, Lunec, Joe and Woollard, Kevin (2003). Dietary supplementation with vitamin C but not vitamin E reduces constitutive expression of ICAM-1 in peripheral blood monocytes of normal subjects with low plasma vitamin C levels. IN: SFRBM's 10th Annual Meeting. 2003-11-01. (Unpublished)

Grant, Melissa, Powers, Hilary, Moat, Stuart, McDowell, Ian and Griffiths, Helen R. (2003). Folate supplementation and methylene tetrahydrofolate reductase genotype neither quantitatively nor qualitatively modulates plasma protein oxidation. IN: SFRBM's 10th Annual Meeting. 2003-11-01. (Unpublished)

Phillips, Darren and Griffiths, Helen R. (2003). Mononuclear cell responses of apoptosis in T cells and growth arrest in monocytes to synthetic ceramide are mediated by loss of cytosolic peroxide. IN: SFRBM's 10th Annual Meeting. 2003-11-01.

Patent

Ma, Xianghong (2011). VIBRATING MICROPLATE BIOSENSING FOR CHARACTERISING PROPERTIES OF BEHAVIOUR BIOLOGICAL CELLS. G01N29/02.

Ma, Xianghong (2009). Characterising properties or behavior of biological cells. G01N27/00.

This list was generated on Sun Jan 20 00:58:10 2019 GMT.