Browse by Aston Author

2024

O'Hagan, David, Spurling, Dominic E., Baker, Emily J., Kingsley-Moore, George, Ppadath, Rifahath Mon Neyya, More, Nachiket D., Al-Maharik, Nawaf D., Harrison, James and Cox, Jonathan A. G. (2024). Aryl‐fluorocyclopropane β‐lactams with activity against Mycobacteroides abscessus and Mycobacterium bovis BCG. European Journal of Organic Chemistry ,

2022

Gibson, Savannah E. R., Harrison, James, Molloy, Antonia and Cox, Jonathan A. G. (2022). Cholesterol-dependent activity of dapsone against non-replicating persistent mycobacteria. Microbiology, 168 (12),

Nolan, Victoria C, Harrison, James and Cox, Jonathan A G (2022). Manuka honey in combination with azithromycin shows potential for improved activity against Mycobacterium abscessus. The Cell Surface, 8 ,

Nolan, Victoria, Harrison, James and Cox, Jonathan A.G. (2022). In vitro synergy between manuka honey and amikacin against Mycobacterium abscessus complex shows potential for nebulisation therapy. Microbiology, 168 (9),

Nolan, Victoria C., Rafols, Laia, Harrison, James, Soldevila-Barreda, Joan J., Crosatti, Marialuisa, Garton, Natalie J., Wegrzyn, Malgorzata, Timms, Danielle L., Seaton, Colin C., Sendron, Helen, Azmanova, Maria, Barry, Nicolas P.E., Pitto-Barry, Anaïs and Cox, Jonathan A.G. (2022). Indole-containing arene-ruthenium complexes with broad spectrum activity against antibiotic-resistant bacteria. Current Research in Microbial Sciences, 3 ,

2021

Harrison, James, Weaver, John A., Desai, Maya and Cox, Jonathan A.G. (2021). In vitro efficacy of relebactam versus avibactam against Mycobacterium abscessus complex. The Cell Surface, 7 ,

Molloy, Antonia, Harrison, James, McGrath, John S., Owen, Zachary, Smith, Clive, Liu, Xin, Li, Xin and Cox, Jonathan A. G. (2021). Microfluidics as a Novel Technique for Tuberculosis: From Diagnostics to Drug Discovery. Microorganisms, 9 (11),

2020

Anagani, B., Singh, J., Bassin, J.p., Besra, G.s., Benham, C., Reddy, T.r.k., Cox, J.A.G. and Goyal, M. (2020). Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds. The Cell Surface, 6 ,

Nolan, Victoria C., Harrison, James, Wright, John E. E. and Cox, Jonathan A. G. (2020). Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections: A Systematic Review. Antibiotics, 9 (11), pp. 1-24.

Burke, Christopher, Jankute, Monika, Moynihan, Patrick, Gonzalez del Rio, Ruben, Li, Xiaojun, Esquivias, Jorge, Lelièvre, Joël, Cox, Jonathan A. G., Sacchettini, James and Besra, Gurdyal S. (2020). Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline. FASEB BioAdvances, 2 (10), pp. 600-612.

Ahmed, Rabia, Bashir, Amreen, Brown, James, Cox, Jonathan A.G., Hilton, Anthony, Jordan, Sam, Theodosiou, Eirini and Worthington, Tony (2020). Aston University's Antimicrobial Resistance (AMR) Roadshow: raising awareness and embedding knowledge of AMR in key stage 4 learners:raising awareness and embedding knowledge of AMR in key stage 4 learners. Infection Prevention in Practice, 2 (2),

Ahmed, Rabia, Bashir, Amreen, Brown, James E P, Cox, Jonathan A G, Hilton, Anthony C, Hilton, Charlotte E, Lambert, Peter A, Theodosiou, Eirini, Tritter, Jonathan Q, Watkin, Samuel J and Worthington, Tony (2020). The drugs don't work:evaluation of educational theatre to gauge and influence public opinion on antimicrobial resistance. Journal of Hospital Infection, 104 (2), pp. 193-197.

Lopeman, Rose C., Harrison, James, Rathbone, Dan, Desai, Maya, Lambert, Peter and Cox, Jonathan A.G. (2020). Effect of Amoxicillin in combination with Imipenem-Relebactam against Mycobacterium abscessus. Scientific Reports, 10 (1),

2019

Harrison, James and Cox, Jonathan A. G. (2019). Changing the Rules of TB-Drug Discovery. Journal of Medicinal Chemistry, 62 (23), pp. 10583-10585.

Nolan, Victoria C., Harrison, James and Cox, Jonathan A. G. (2019). Dissecting the Antimicrobial Composition of Honey. Antibiotics, 8 (4),

Lopeman, Rose C., Harrison, James, Desai, Maya and Cox, Jonathan A. G. (2019). Mycobacterium abscessus: Environmental Bacterium Turned Clinical Nightmare. Microorganisms, 7 (3),

Cox, Jonathan A.G., Taylor, Rebecca C., Brown, Alistair K., Attoe, Samuel, Besra, Gurdyal S. and Fütterer, Klaus (2019). Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation. Acta Crystallographica Section D: Structural Biology, 75 (Pt 1), pp. 101-108.

2018

Gibson, Savannah E.R., Harrison, James and Cox, Jonathan A.G. (2018). Modelling a silent epidemic:A review of the in vitro models of latent tuberculosis. Pathogens, 7 (4),

Trofimov, Valentin, Kicka, Sébastien, Mucaria, Sabrina, Hanna, Nabil, Ramon-Olayo, Fernando, Del Peral, Laura Vela Gonzalez, Lelièvre, Joël, Ballell, Lluís, Scapozza, Leonardo, Besra, Gurdyal S., Cox, Jonathan A.G. and Soldati, Thierry (2018). Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets. Scientific Reports, 8 (1),

2017

Abrahams, Katherine A., Cox, Jonathan A.G., Fütterer, Klaus, Rullas, Joaquín, Ortega-Muro, Fátima, Loman, Nicholas J., Moynihan, Patrick J., Pérez-Herrán, Esther, Jiménez, Elena, Esquivias, Jorge, Barros, David, Ballell, Lluís, Alemparte, Carlos and Besra, Gurdyal S. (2017). Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface. Scientific Reports, 7 ,

Cox, Jonathan A.G. and Worthington, Tony (2017). The 'Antibiotic Apocalypse' - scaremongering or scientific reporting? Trends in Microbiology, 25 (3), pp. 167-169.

2016

Cox, Jonathan A.G., Mugumbate, Grace, Vela-Glez del Peral, Laura, Jankute, Monika, Abrahams, Katherine A., Jervis, Peter, Jackenkroll, Stefan, Perez, Arancha, Alemparte, Carlos, Esquivias, Jorge, Lelièvre, Joël, Ramon, Fernando, Barros, David, Ballell, Lluis and Besra, Gurdyal S. (2016). Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen. Scientific Reports, 6 ,

Cox, Jonathan A.G. (2016). Drug development:the cell wall as a drug target. International Journal of Mycobacteriology, 5 (Supple), S156.

Abrahams, Katherine A., Chung, Chun-Wa, Ghidelli-Disse, Sonja, Rullas, Joaquín, Rebollo-López, María José, Gurcha, Sudagar S., Cox, Jonathan A.G., Mendoza, Alfonso, Jiménez-Navarro, Elena, Martínez-Martínez, María Santos, Neu, Margarete, Shillings, Anthony, Homes, Paul, Argyrou, Argyrides, Casanueva, Ruth, Loman, Nicholas J., Moynihan, Patrick J., Lelièvre, Joël, Selenski, Carolyn, Axtman, Matthew, Kremer, Laurent, Bantscheff, Marcus, Angulo-Barturen, Iñigo, Izquierdo, Mónica Cacho, Cammack, Nicholas C., Drewes, Gerard, Ballell, Lluis, Barros, David, Besra, Gurdyal S. and Bates, Robert H. (2016). Identification of KasA as the cellular target of an anti-tubercular scaffold. Nature Communications, 7 ,

Cox, Jonathan A.G., Abrahams, Katherine A., Alemparte, Carlos, Ghidelli-Disse, Sonja, Rullas, Joaquín, Angulo-Barturen, Iñigo, Singh, Albel, Gurcha, Sudagar S., Nataraj, Vijayashankar, Bethell, Stephen, Remuiñán, Modesto J., Encinas, Lourdes, Jervis, Peter J., Cammack, Nicholas C., Bhatt, Apoorva, Kruse, Ulrich, Bantscheff, Marcus, Fütterer, Klaus, Barros, David, Ballell, Lluis, Drewes, Gerard and Besra, Gurdyal S. (2016). THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nature Microbiology, 1 ,

2015

Mugumbate, G, Abrahams, KA, Cox, JA, Papadatos, G, van, Westen G, Lelièvre, J, Calus, ST, Loman, NJ, Ballell, L, Barros, D, Overington, JP and Besra, GS (2015). Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation. PLoS ONE, 10 (3),

2014

Gurcha, SS, Usha, V, Cox, JA, Fütterer, K, Abrahams, KA, Bhatt, A, Alderwick, LJ, Reynolds, RC, Loman, NJ, Nataraj, V, Alemparte, C, Barros, D, Lloyd, AJ, Ballell, L, Hobrath, JV and Besra, GS (2014). Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. PLoS ONE, 9 (11),

2012

Abrahams, KA, Cox, JA, Spivey, VL, Loman, NJ, Pallen, MJ, Constantinidou, C, Fernández, R, Alemparte, C, Remuiñán, MJ, Barros, D, Ballell, L and Besra, GS (2012). Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB. PLoS ONE, 7 (12),