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Dilworth, Marvin V., Piel, Mathilde S., Bettaney, Kim E., Ma, Pikyee, Luo, Ji, Sharples, David, Poyner, David R., Gross, Stephane R., Moncoq, Karine, J. F. Henderson, Peter, Miroux, Bruno and Bill, Roslyn M. (2018). Microbial expression systems for membrane proteins. Methods ,

Uddin, Romez, Simms, John and Poyner, David (2018). Functional characterisation of G protein-coupled receptors. Methods ,

Hay, Debbie L., Garelja, Michael L., Poyner, David R and Walker, Christopher S. (2017). Update on the pharmacology of calcitonin/CGRP family of peptides:IUPHAR Review 25. British Journal of Pharmacology, In pre ,

Woolley, Michael J., Reynolds, Christopher A., Simms, John, Walker, Christopher S., Mobarec, Juan Carlos, Garelja, Michael L., Conner, Alex C., Poyner, David R. and Hay, Debbie L. (2017). Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs. Biochemical Pharmacology, in pre ,

Routledge, Sarah J., Ladds, Graham and Poyner, David R. (2017). The effects of RAMPs upon cell signalling. Molecular and Cellular Endocrinology, in pre ,

Weston, Cathryn, Winfield, Ian, Harris, Matthew, Hodgson, Rose, Shah, Archna, Dowell, Simon J., Mobarec, Juan Carlos, Woodlock, David A., Reynolds, Christopher A., Poyner, David R., Watkins, Harriet A. and Ladds, Graham (2016). Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors. Journal of Biological Chemistry, 291 (42), pp. 21925-21944.

Watkins, Harriet A., Chakravarthy, Madhuri, Abhayawardana, Rekhati S., Gingell, Joseph J., Garelja, Michael, Pardamwar, Meenakshi, McElhinney, James M.W.R., Lathbridge, Alex, Constantine, Arran, Harris, Paul W.R., Yuen, Tsz-Ying, Brimble, Margaret A., Barwell, James, Poyner, David R., Woolley, Michael J., Conner, Alex C., Pioszak, Augen A., Reynolds, Christopher A. and Hay, Debbie L. (2016). Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties. Journal of Biological Chemistry, 291 (22), pp. 11657-11675.

Gingell, Joseph J., Simms, John, Barwell, James, Poyner, David R., Watkins, Harriet A., Pioszak, Augen A., Sexton, Patrick M. and Hay, Debbie L. (2016). An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology. Cell Discovery, 2 ,

Wheatley, Mark, Charlton, Jack, Jamshad, Mohammed, Routledge, Sarah J., Bailey, Sian, La-Borde, Penelope J., Azam, Maria T., Logan, Richard T., Bill, Roslyn M., Dafforn, Tim R. and Poyner, David R. (2016). GPCR-styrene maleic acid lipid particles (GPCR-SMALPs):their nature and potential. Biochemical Society Transactions, 44 (2), pp. 619-623.

Weston, Cathryn, Lu, Jing, Li, Naichang, Barkan, Kerry, Richards, Gareth O., Roberts, David J., Skerry, Timothy M., Poyner, David, Pardamwar, Meenakshi, Reynolds, Christopher A., Dowell, Simon J., Willars, Gary B. and Ladds, Graham (2015). Modulation of glucagon receptor pharmacology by Receptor Activity-modifying Protein-2 (RAMP2). Journal of Biological Chemistry, 290 (38), pp. 23009-23022.

Booe, Jason M., Walker, Christopher S., Barwell, James, Kuteyi, Gabriel, Simms, John, Jamaluddin, Muhammad A., Warner, Margaret L., Bill, Roslyn M., Harris, Paul W., Brimble, Margaret A., Poyner, David R., Hay, Debbie L. and Pioszak, Augen A. (2015). Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor. Molecular Cell, 58 (6), pp. 1040-1052.

Jamshad, Mohammed, Charlton, Jack, Lin, Yu-Pin, Routledge, Sarah J, Bawa, Zharain, Knowles, Timothy J., Overduin, Michael, Dekker, Niek, Dafforn, Tim R., Bill, Roslyn M., Poyner, David R. and Wheatley, Mark (2015). G-protein-coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent. Bioscience Reports, 35 (2),

Bawa, Zharain, Routledge, Sarah J., Jamshad, Mohammed, Clare, Michelle, Sarkar, Debasmita, Dickerson, Ian, Ganzlin, Markus, Poyner, David R. and Bill, Roslyn M. (2014). Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. Microbial Cell Factories, 13 (1),

Watkins, H.A., Walker, C.S., Ly, K.N., Bailey, R.J., Barwell, J., Poyner, D.R. and Hay, D.L. (2014). Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor:implications for adrenomedullin and calcitonin gene-related peptide pharmacology. British Journal of Pharmacology, 171 (3), pp. 772-788.

Routledge, Sarah J., Poyner, David R. and Bill, Roslyn M. (2014). Antifoams:the overlooked additive? Pharmaceutical Bioprocessing, 2 (2), pp. 103-106.

Hay, Debbie L., Harris, Paul W.R., Kowalczyk, Renata, Brimble, Margaret A., Rathbone, Dan L, Barwell, James, Conner, Alex C. and Poyner, David R. (2014). Structure-activity relationships of the N-terminus of calcitonin gene-related peptide:key roles of alanine-5 and threonine-6 in receptor activation. British Journal of Pharmacology, 171 (2), pp. 415-426.

Vohra, Shabana, Taddese, Bruck, Conner, Alex C., Poyner, David R., Hay, Debbie L., Barwell, James, Reeves, Philip J., Upton, Graham J.G. and Reynolds, Christopher A. (2013). Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies. Journal of the Royal Society Interface, 10 (79),

Wootten, D., Lindmark, H., Kadmiel, M., Willcockson, H., Caron, K.M., Barwell, J., Drmota, T. and Poyner, D. (2013). Receptor Activity Modifying Proteins (RAMPs) interact with the VPAC2 Receptor and CRF1 receptors and modulate their function. British Journal of Pharmacology, 168 (4), pp. 822-834.

Barwell, James, Wheatley, Mark, Conner, Alex C., Taddese, Bruck, Vohra, Shabana, Reynolds, Christopher A. and Poyner, David R. (2013). The activation of the CGRP receptor. Biochemical Society Transactions, 41 (1), pp. 180-184.

Barwell, James, Gingell, Joseph J., Watkins, Harriet A., Archbold, Julia K., Poyner, David R. and Hay, Debbie L. (2012). Calcitonin and calcitonin receptor-like receptors:common themes with family B GPCRs? British Journal of Pharmacology, 166 (1), pp. 51-65.

Barwell, James, Woolley, Michael J., Wheatley, Mark, Conner, Alex C. and Poyner, David R (2012). The role of the extracellular loops of the CGRP receptor, a family B GPCR. Biochemical Society Transactions, 40 (2), pp. 433-437.

Wheatley, M., Wootten, Denise, Conner, Matthew T., Simms, John, Kendrick, R., Logan, R.T., Poyner, David R. and Barwell, James (2012). Lifting the lid on GPCRs:the role of extracellular loops. British Journal of Pharmacology, 165 (6), pp. 1688-1703.

Sexton, Patrick M., Poyner, David R., Simms, John, Christopoulos, Arthur and Hay, Debbie L. (2012). RAMPs as drug targets. Advances in Experimental Medicine and Biology, 744 , pp. 61-74.

Barwell, James, Conner, Alex C. and Poyner, David R (2011). Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function. BBA - Molecular Cell Research, 1813 (10), pp. 1906-1916.

Jamshad, Mohammed, Lin, Yu-Pin, Knowles, Timothy J., Parslow, Rosemary A., Harris, Craig, Wheatley, Mark, Poyner, David R., Bill, Roslyn M., Thomas, Owen R.T., Overduin, Michael and Dafforn, Tim R. (2011). Surfactant-free purification of membrane proteins with intact native membrane environment. Biochemical Society Transactions, 39 (3), pp. 813-818.

Qi, Tao, Ly, Kien, Poyner, David R., Christopoulos, George, Sexton, Patrick M. and Hay, Debbie L. (2011). Structure-function analysis of amino acid 74 of human RAMP1 and RAMP3 and its role in peptide interactions with adrenomedullin and calcitonin gene-related peptide receptors. Peptides, 32 (5), pp. 1060-1067.

Hay, Debbie L., Walker, Christopher S. and Poyner, David R (2011). Adrenomedullin and calcitonin gene-related peptide receptors in endocrine-related cancers:opportunities and challenges. Endocrine-related Cancer, 18 (1), C1-14.

Chugunov, Anton O., Simms, John, Poyner, David R., Dehouck, Yves, Rooman, Marianne, Gilis, Dimitri and Langer, Ingrid (2010). Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation. Molecular Pharmacology, 78 (3), pp. 394-401.

Barwell, James, Miller, Philip S., Donnelly, Dan and Poyner, David R. (2010). Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor. Peptides, 31 (1), pp. 170-176.

Robinson, Samuel D, Aitken, Jacqueline F, Bailey, Richard J, Poyner, David R and Hay, Debbie L (2009). Novel peptide antagonists of adrenomedullin and calcitonin gene-related peptide receptors:identification, pharmacological characterization, and interactions with position 74 in receptor activity-modifying protein 1/3. Journal of Pharmacology and Experimental Therapeutics, 331 (2), pp. 513-521.

Sexton, Patrick M., Poyner, David R., Simms, John, Christopoulos, Arthur and Hay, Debbie L. (2009). Modulating receptor function through RAMPs:can they represent drug targets in themselves? Drug Discovery Today, 14 (7-8), pp. 413-419.

Bonander, Nicklas, Darby, Richard A.J., Grgic, Ljuban, Bora, Nagamani, Wen, Jikai, Brogna, Saverio, Poyner, David R., O'Neill, Michael A. A. and Bill, Roslyn M. (2009). Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield. Microbial Cell Factories, 8 (10),

Simms, John, Hay, Debbie L., Bailey, Richard J., Konycheva, Galina, Bailey, Graham, Wheatley, Mark and Poyner, David R. (2008). Structure-function analysis of RAMP1 by Alanine Mutagenesis. Biochemistry, 48 (1), pp. 198-205.

Conner, Matthew, Hicks, Matthew R., Dafforn, Tim, Knowles, Timothy J., Ludwig, Christian, Staddon, Susan, Overduin, Michael, Günther, Ulrich L., Thome, Johannes, Wheatley, M., Poyner, David R. and Conner, Alex C. (2008). Functional and biophysical analysis of the C-terminus of the CGRP-receptor; a family B GPCR. Biochemistry, 47 (32), pp. 8434-8444.

Poyner, David R. and Wheatley, M. (2007). Family resemblances? Ligand binding and activation of family A and B G-protein-coupled receptors. Biochemical Society Transactions, 35 (4), pp. 707-708.

Conner, A.C., Simms, J., Barwell, J., Wheatley, M. and Poyner, D.R. (2007). Ligand binding and activation of the CGRP receptor. Biochemical Society Transactions, 35 (4), pp. 729-732.

Conner, Alex C., Simms, John, Conner, Matthew T., Wootten, Denise L., Wheatley, Mark and Poyner, David R. (2006). Diverse functional motifs within the three intracellular loops of the CGRP1 receptor. Biochemistry, 45 (43), pp. 12976-12985.

Hay, Debbie L., Poyner, David R. and Sexton, Patrick M. (2006). GPCR modulation by RAMPs. Pharmacology and Therapeutics, 109 (1-2), pp. 173-197.

Hay, Debbie L., Christopoulos, George, Christopoulos, Arthur, Poyner, David R. and Sexton, Patrick M. (2005). Pharmacological discrimination of calcitonin receptor:receptor activity-modifying protein complexes. Molecular Pharmacology, 67 (5), pp. 1655-1665.

Conner, Alex C., Hay, Debbie L., Simms, John, Howitt, Stephen G., Schindler, Marcus, Smith, David M., Wheatley, Mark and Poyner, David R. (2005). A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling:implications for family B G-protein-coupled receptors. Molecular Pharmacology, 67 (1), pp. 20-31.

Hay, Debbie L., Poyner, David R. and Smith, David M. (2003). Desensitisation of adrenomedullin and CGRP receptors. Regulatory peptides, 112 (1-3), pp. 139-145.

Howitt, Stephen G., Kilk, Kalle, Wang, Yang, Smith, David M., Langel, Ulo and Poyner, David R. (2003). The role of the 8-18 helix of CGRP 8-37 in mediating high affinity binding to CGRP receptors; coulombic and steric interactions. British Journal of Pharmacology, 138 (2), pp. 325-332.

Conner, Alex C., Hay, Debbie L., Howitt, S.G., Kilk, K., Langel, U., Wheatley, Mark, Smith, David M. and Poyner, David R. (2002). Interaction of calcitonin-gene-related peptide with its receptors. Biochemical Society Transactions, 30 (4), pp. 451-455.

Poyner, David R., Sexton, Patrick M., Marshall, Ian, Smith, David M., Quirion, Remi, Born, Walter, Muff, Roman, Fischer, Jan A. and Foord, Steven M. (2002). International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacological Reviews, 54 (2), pp. 233-246.

Adams, Eric F., Symowski, Hedwig, Buchfelder, Michael and Poyner, David R. (2000). A polymorphism in the growth hormone (GH)-releasing hormone (GHRH) receptor gene is associated with elevated response to GHRH by human pituitary somatotrophinomas in vitro. Biochemical and Biophysical Research Communications, 275 (1), pp. 33-36.

Poyner, David R., Taylor, Gillian M., Tomlinson, A. Elaine, Richardson, Alan G. and Smith, David M. (1999). Characterization of receptors for calcitonin gene-related peptide and adrenomedullin on the guinea-pig vas deferens. British Journal of Pharmacology, 126 (5), pp. 1276-1282.

Spiers, Ian D., Barker, Christopher J., Chung, Sung-Kee, Chang, Young-Tae, Freeman, Sally, Gardiner, John M., Hirst, Peter H., Lambert, Peter A., Michell, Robert H., Poyner, David R., Schwalbe, Carl H., Smith, Anthony W. and Solomons, Kevin R. H. (1996). Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (+/-)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates. Carbohydrate Research, 282 (1), pp. 81-99.

Coulson, Judy M., Poyner, David, Chantry, Andrew, Irwin, William J. and Akhtar, Saghir (1996). A nonantisense sequence-selective effect of a phosphorothioate oligodeoxynucleotide directed against the epidermal growth factor receptor in A431 cells. Molecular Pharmacology, 50 (2), pp. 314-325.

Gosling, M., Poyner, David and Smith, J.W. (1996). Effects of arachidonic acid upon the volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Journal of Physiology, 493 (3), pp. 613-623.

Gosling, Martin, Smith, J.W. and Poyner, David R. (1995). Characterization of a volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Journal of Physiology, 485 (3), pp. 671-682.

Smith, Anthony W., Poyner, David R., Hughes, H.K. and Lambert, Peter A. (1994). Siderophore activity of myo-inositol hexakisphosphate in Pseudomonas aeruginosa. Journal of Bacteriology, 176 (12), pp. 3455-3459.

Gosling, Martin, Smith, John W. and Poyner, David R. (1994). Regulation of membrane potential by G-protein-coupled receptors in L6 skeletal myocytes: the role of second messengers. Biochemical Society Transactions, 21 (4), 433S.

Gosling, Martin, Poyner, David R. and Smith, John W. (1993). Stimulation of chloride secretion and adenylate cyclase secretion in human colonic derived cell lines by calcitonin gene-related peptide. Biochemical Society Transactions, 21 (4), 434S.

Hawkins, Phillip T., Poyner, David R., Jackson, T.R., Letcher, A.J., Lander, Dawn and Irvine, R.F. (1993). Inhibition of iron-catalysed hydroxyl radical formation by inositol polyphosphates: a possible physiological function for myo-inositol hexakisphosphate. Biochemical Journal, 294 , pp. 929-934.

Poyner, David R., Cooke, F., Hanley, Michael R., Reynolds, D.J. and Hawkins, Phillip T. (1993). Characterization of metal ion-induced [3H]inositol hexakisphosphate binding to rat cerebellar membranes. Journal of Biological Chemistry, 268 (2), pp. 1032-1038.

D'Santos, C.S., Gatti, A., Poyner, David R. and Hanley, Michael R. (1992). Stimulation of adenylate cyclase by amylin in CHO-K1 cells. Molecular Pharmacology, 41 (5), pp. 894-899.

Poyner, David R. (1992). Calcitonin gene-related peptide:multiple actions, multiple receptors. Pharmacology and Therapeutics, 56 (1), pp. 23-51.

Hawkins, Phillip T., Reynolds, D.J.M., Poyner, David R. and Hanley, Michael R. (1990). Identification of a novel inositol phosphate recognition site: specific [3H]inositol hexakisphosphate binding to brain regions and cerebellar membranes. Biochemical and Biophysical Research Communications, 167 (2), pp. 819-827.

Poyner, David R., Birdsall, N.J., Curtis, C., Eveleigh, P., Hulme, E.C., Pedder, E.K. and Wheatley, Mark (1989). Binding and hydrodynamic properties of muscarinic receptor subtypes solubilized in 3-(3-cholamidopropyl)dimethylammonio-2-hydroxy-1-propanesulfonate. Molecular Pharmacology, 36 (3), pp. 420-429.

Gosling, Martin, Smith, J.W. and Poyner, David R. Activation of calcium-sensitive potassium channels in L6 skeletal myocytes by arginine vasopressin requires extracellular calcium. Biochemical and Biophysical Research Communications, 217 (3), pp. 1163-1168.

Smith, David M., Coppock, H.A., Withers, D.J., Owji, A.A., Hay, D.L., Choksi, T.P., Chakravarty, P., Legon, S. and Poyner, David R. Adrenomedullin: receptor and signal transduction. Biochemical Society Transactions, 30 (4), pp. 432-437.

Poyner, David R., Hay, Debbie L. and Conner, Alex C. CGRP receptor antagonists:design and screening. Expert Opinion on Drug Discovery, 4 (12), pp. 1253-1265.

Hay, Debbie L., Poyner, David and Dickerson, Ian CGRP receptor heterogeneity:a role for receptor component protein? Trends in Endocrinology and Metabolism, 14 (1), pp. 3-4.

Brain, Susan. D., Poyner, David R. and Hill, Raymond G. CGRP receptors:A headache to study, but will antagonists prove therapeutic in migraine? Trends in Pharmacological Sciences, 23 (2), pp. 51-53.

Hay, Debbie L., Howitt, Stephen G., Conner, Alex C., Schindler, Marcus, Smith, David M. and Poyner, David R. CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors:a comparison of effects of adrenomedullin 22-52, CGRP 8-37 and BIBN4096BS. British Journal of Pharmacology, 140 (3), pp. 477-486.

Hay, Debbie L. and Poyner, David R. Calcitonin gene-related peptide, adrenomedullin and flushing. Maturitas, 64 (2), pp. 104-108.

Poyner, David R., Hawkins, Phillip T., Benton, H.P. and Hanley, Michael R. Changes in inositol lipids and phosphates after stimulation of the MAS-transfected NG115-401L-C3 cell line by mitogenic and non-mitogenic stimuli. Biochemical Journal, 271 (3), pp. 605-611.

Takhshid, Mohammad A., Poyner, David R., Chabot, Jean-Guy, Fournier, Alain, Ma, Weiya, Zheng, Wen-Hua, Owji, Ali A. and Quirion, Remi Characterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene-related peptide (CGRP) receptors in dissociated rat spinal cord cell culture. British Journal of Pharmacology, 148 (4), pp. 459-468.

Smith, Stephen N., Armstrong, Richard A., Bird, Roger A., Chohan, Rita, Hartell, Nick A. and Poyner, David A. Characterization of FITC-conjugated lectin binding to Candida albicans. Mycologia, 93 (3), pp. 422-431.

Simms, John, Hay, Debbie L., Wheatley, Mark and Poyner, David R. Characterization of the structure of RAMP1 by mutagenesis and molecular modeling. Biophysical Journal, 91 (2), pp. 662-669.

Lattmann, Eric, Billington, David C., Poyner, David R., Arayarat, Pornthip, Howitt, Stephen B., Lawrence, Spencer and Offel, Michael Combinatorial solid phase synthesis of multiply substituted 1,4-benzodiazepines and affinity studies on the CCK2 receptor (Part 1). Drug Design and Discovery, 18 (1), pp. 9-21.

Choksi, Tejal, Hay, Debbie L., Legon, Stephen, Poyner, David R., Hagner, Stefanie, Bloom, Stephen R. and Smith, David M. Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines. British Journal of Pharmacology, 136 (5), pp. 784-792.

Gosling, Martin, Akhtar, Saghir, Smith, J.W. and Poyner, David R. Direct inhibitory effects of an antisense oligodeoxynucleotide upon the volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Biochemical and Biophysical Research Communications, 227 (1), pp. 15-19.

Foster, Alexander J., Bird, Roger A., Kelly, Steven L., Nishimura, Kazuko, Poyner, David, Taylor, Stephen and Smith, Stephen N. FITC-lectin avidity of Cryptococcus neoformans cell wall and capsular components. Mycologia, 96 (1), pp. 1-8.

Bailey, Richard J., Bradley, Joshua W.I., Poyner, David R, L. Rathbone, Daniel and Hay, Debbie L. Functional characterization of two human receptor activity-modifying protein 3 variants. Peptides, 31 (4), pp. 579-584.

Conner, A.C., Simms, J., Hay, D.L., Mahmoud, K., Howitt, S.G., Wheatley, M. and Poyner, D.R. Heterodimers and family-B GPCRs:RAMPs, CGRP and adrenomedullin. Biochemical Society Transactions, 32 (5), pp. 843-846.

Kuteyi, G., Barwell, J. and Poyner, D. Identifying key residues important for CGRP binding to its receptor. FEBS journal, 280 (S1), p. 405.

Hanley, Michael R., Poyner, David R. and Hawkins, Phillip T. Inositol phospholipids and phosphates for investigation of intact cell phospholipase C substrates and products. Methods in Enzymology, 197 , pp. 149-158.

Hirst, Peter H., Riley, A.M., Mills, S.J., Spiers, Ian D., Poyner, David R., Freeman, Sally, Potter, B.V. and Smith, Anthony W. Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa. Journal of Applied Microbiology, 86 (3), pp. 537-543.

Hay, Debbie L., Poyner, David R. and Quirion, Remi International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor. Pharmacological Reviews, 60 (2), pp. 143-145.

Weston, C., Poyner, D., Patel, V., Dowell, S. and Ladds, G. Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast. British Journal of Pharmacology, 171 (15), pp. 3651-3665.

Stanley, Alison F., Hawkins, Phillip T., Poyner, David R. and Hanley, Michael R. Metabolism of myo-inositol pentakisphosphates in mammalian brain. Biochemical Society Transactions, 20 (2), 149S.

Denny, Brian J., Lambert, Peter A. and Poyner, David R. Molecular modelling of the human formyl peptide receptor. Biochemical Society Transactions, 23 (1), 96S.

Poyner, David R. Molecular pharmacology of receptors for calcitonin-gene-related peptide, amylin and adrenomedullin. Biochemical Society Transactions, 25 (3), pp. 1032-1036.

Tomlinson, A. Elaine and Poyner, David Multiple receptors for calcitonin gene-related peptide and amylin on guinea-pig ileum and vas deferens. British Journal of Pharmacology, 117 (6), pp. 1362-1368.

Miller, Philip S., Barwell, James, Poyner, David R., Wigglesworth, Mark J., Garland, Stephen L. and Donnelly, Dan Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74. Biochemical and Biophysical Research Communications, 391 (1), pp. 437-442.

Poyner, D.R., Andrew, D.P., Brown, D., Bose, C. and Hanley, M.R. Pharmacological characterization of a receptor for calcitonin gene-related peptide on rat, L6 myocytes. British Journal of Pharmacology, 105 (2), pp. 441-447.

Barwell, James, Wootten, Denise, Simms, John, Hay, Debbie L. and Poyner, David R. RAMPs and CGRP receptors. Advances in Experimental Medicine and Biology, 744 , pp. 13-24.

Hay, Debbie L., Walker, Christopher S., Gingell, Joseph J., Ladds, Graham, Reynolds, Christopher A. and Poyner, David R. Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins. Biochemical Society Transactions, 44 (2), pp. 568-573.

Poyner, David R., Hanley, Michael R., Jackson, T.R. and Hawkins, Phillip T. Receptor regulation of phosphoinositide 3-hydroxykinase in the NG115-401L-C3 neuronal cell line: stimulation by insulin-like growth factor-I. Biochemical Journal, 290 , pp. 901-905.

Walker, Christopher S., Conner, Alex C, Poyner, David R, Hay, Debbie L. and Conner, Alex C. Regulation of signal transduction by calcitonin gene-related peptide receptors. Trends in Pharmacological Sciences, 31 (10), pp. 476-483.

Woolley, Michael J., Simms, John, Uddin, Sifat, Poyner, David R. and Conner, Alex C. Relative antagonism of mutants of the CGRP receptor extracellular loop 2 domain (ECL2) using a truncated competitive antagonist (CGRP8-37):evidence for the dual involvement of ECL2 in the two-domain binding model. Biochemistry, 56 (30), pp. 3877-3880.

Poyner, David R. and Hay, Debbie L. Secretin family (Class B) G protein-coupled receptors - from molecular to clinical perspectives. British Journal of Pharmacology, 166 (1), pp. 1-3.

Akhtar, Saghir, Dunnion, Debbie, Poyner, David, Ackroyd, John, Bibby, Mike and Double, John Sequence and chemistry requirements for a novel aptameric oligonucleotide inhibitor of EGF receptor tyrosine kinase activity. Biochemical Pharmacology, 63 (12), pp. 2187-2195.

Poyner, David R., Jackson, Trevor R. and Hawkins, Phillip T. Stimulation of phosphatidylinositol-3-kinase by insulin-like growth factor 1 and other agonists. Biochemical Society Transactions, 20 (2), 140S.

Poyner, David R., Soomets, Ursel, Howitt, Stephen G. and Langel, Ulo Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells:Studies with chimeric and other peptides. British Journal of Pharmacology, 124 (8), pp. 1659-1666.

Watkins, Harriet A., Rathbone, Dan L., Barwell, James, Hay, Debbie L. and Poyner, David R Structure-activity relationships for α-calcitonin gene-related peptide. British Journal of Pharmacology, 170 (7), pp. 1308-1322.

Qi, Tao, Simms, John, Bailey, Richard J., Wheatley, Mark, L. Rathbone, Daniel, Hay, Debbie L. and Poyner, David R Structure-function analysis of RAMP1-RAMP3 chimeras. Biochemistry, 49 (3), pp. 522-531.

Lattmann, Eric, Sattayasai, Jintana, Billington, David C., Poyner, David R., Puapairoj, Prapawadee, Tiamkao, Siriporn, Airarat, Wanchai, Singh, Harjit, Offel, Michael and Poyner, David Synthesis and evaluation of N1-substituted-3-propyl-1,4-benzodiazepine-2-ones as cholecystokinin (CCK2) receptor ligands. Journal of Pharmacy and Pharmacology, 54 (6), pp. 827-834.

Lattmann, Eric, Billington, David C., Poyner, David, Howitt, Stephen B. and Offel, Michael Synthesis and evaluation of asperlicin analogues as non-peptidal cholecystokinin-antagonists. Drug Design and Discovery, 17 (3), pp. 219-230.

Woolley, Michael J., Simms, John, Mobarec, Juan Carlos, Reynolds, Christopher A., Poyner, David R. and Conner, Alex C. Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach. Molecular and Cellular Endocrinology, in pre ,

Hay, Debbie L., Howitt, Stephen G., Conner, Alex C., Doods, Henri, Schindler, Marcus and Poyner, David R. A comparison of the actions of BIBN4096BS and CGRP 8-37 on CGRP and adrenomedullin receptors expressed on SK-N-MC, L6, Col 29 and Rat 2 cells. British Journal of Pharmacology, 137 (1), pp. 80-86.

Stephens, L.R., Hawkins, Phillip T., Stanley, Alison F., Moore, T., Poyner, David R., Morris, P.J., Hanley, Michael R., Kay, R.R. and Irvine, R.F. myo-inositol pentakisphosphates. Structure, biological occurrence and phosphorylation to myo-inositol hexakisphosphate. Biochemical Journal, 275 , pp. 485-499.

Conner, Alex C. and Poyner, David R. The perils of using the human genome sequence:Lessons from CALCRL. Trends in Pharmacological Sciences, 22 (6), p. 272.

Hay, D.L., Conner, A.C., Howitt, S.G., Takhshid, M.A., Simms, J., Mahmoud, K. and Poyner, David The pharmacology of CGRP-responsive receptors in cultured and transfected cells. Peptides, 25 (11), pp. 2019-2026.

Hong, Yanguo, Hay, Debbie L., Quirion, Remi and Poyner, David R. The pharmacology of adrenomedullin 2/intermedin. British Journal of Pharmacology, 166 (1), pp. 110-120.

Hay, Debbie L., Conner, Alex C., Howitt, Stephen G., Smith, David M. and Poyner, David The pharmacology of adrenomedullin receptors and their relationship to CGRP receptors. Journal of Molecular Neuroscience, 22 (1-2), pp. 105-113.

Adams, Eric F., Oikonomou, Eftychia, Bhamrah, Mandeep, Buchfelder, Michael, Mitchell, Rosalind and Poyner, David R. A polymorphism in the growth hormone-releasing hormone receptor gene: clinical significance? Regulatory peptides, 108 (2-3), pp. 125-128.

Hay, Debbie L. and Poyner, David The preclinical pharmacology of BIBN4096BS, a CGRP antagonist. Cardiovascular Therapeutics, 23 (1), pp. 31-42.

Woolley, Michael J., Watkins, Harriet A., Taddese, Bruck, Karakullukcu, Z. Gamze, Barwell, James, Smith, Kevin J., Hay, Debbie L., Poyner, David R., Reynolds, Christopher A. and Conner, Alex C. The role of ECL2 in CGRP receptor activation:a combined modelling and experimental approach. Journal of the Royal Society Interface, 10 (88),

Conner, Alex C., Simms, John, Howitt, Stephen G., Wheatley, Mark and Poyner, David R. The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression. Journal of Biological Chemistry, 281 (3), pp. 1644-1651.

Howitt, Stephen G. and Poyner, David The selectivity and structural determinants of peptide antagonists at the CGRP receptor of rat, L6 myocytes. British Journal of Pharmacology, 121 (5), pp. 1000-1004.

Book Section

Conner, Alex C., Barwell, James, Poyner, David R. and Wheatley, Mark (2011). The use of site-directed mutagenesis to study GPCRs. IN: Receptor signal transduction protocols. Willars, Gary B. and Challiss, R.A. John (eds) Methods in molecular biology (3rd ed). Humana Press.

Poyner, David R. (2008). RAMPs and the modulation of G-protein coupled receptors. IN: Proceeedings of the XXVIII European Section Meeting of the International Society gor Heart Research. Bologna (IT): Monduzzi.

Conner, Alex C., Hay, Debbie L. and Poyner, David R. Characterization of CGRP receptor binding. IN: Current protocols in pharmacology. Wiley.

Poyner, David R. and Wheatley, Mark Preface. IN: G protein-coupled receptors. Poyner, David R. and Wheatley, Mark (eds) Wiley-Blackwell.

This list was generated on Thu Jun 21 00:56:56 2018 BST.