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Number of items: 41.

Article

Bailey, Sian, Harris, Matthew, Barkan, Kerry, Winfield, Ian, Thomas-Harper, Matthew, Simms, John W, Ladds, Graham, Wheatley, Mark and Poyner, David R (2019). Interactions Between RAMP2 And CRF Receptors:The Effect Of Receptor Subtypes, Splice Variants And Cell Context. BBA -Biomembranes, 1861 (5), pp. 997-1003.

Mackie, Duncan I., Al Mutairi, Fuad, Davis, Reema B., Kechele, Daniel O., Nielsen, Natalie R., Snyder, Joshua C., Caron, Marc G., Kliman, Harvey J., Berg, Jonathan S., Simms, John, Poyner, David R. and Caron, Kathleen M. (2018). hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. Journal of Experimental Medicine ,

Simms, John, Uddin, Romez, Sakmar, Thomas P., Gingell, Joseph J., Garelja, Michael L., Hay, Debbie L., Brimble, Margaret A., Harris, Paul W. R., Reynolds, Christopher Arthur and Poyner, David R. (2018). Photoaffinity cross-linking and unnatural amino acid mutagenesis reveal insights into calcitonin gene-related peptide binding to the calcitonin receptor-like receptor/receptor activity-modifying protein 1 (CLR/RAMP1) complex. Biochemistry ,

Dilworth, Marvin V., Piel, Mathilde S., Bettaney, Kim E., Ma, Pikyee, Luo, Ji, Sharples, David, Poyner, David R., Gross, Stephane R., Moncoq, Karine, J. F. Henderson, Peter, Miroux, Bruno and Bill, Roslyn M. (2018). Microbial expression systems for membrane proteins. Methods ,

Uddin, Romez, Simms, John and Poyner, David (2018). Functional characterisation of G protein-coupled receptors. Methods ,

Hay, Debbie L., Garelja, Michael L., Poyner, David R and Walker, Christopher S. (2017). Update on the pharmacology of calcitonin/CGRP family of peptides:IUPHAR Review 25. British Journal of Pharmacology, In pre ,

Woolley, Michael J., Simms, John, Uddin, Sifat, Poyner, David R. and Conner, Alex C. (2017). Relative antagonism of mutants of the CGRP receptor extracellular loop 2 domain (ECL2) using a truncated competitive antagonist (CGRP8-37):evidence for the dual involvement of ECL2 in the two-domain binding model. Biochemistry, 56 (30), pp. 3877-3880.

Woolley, Michael J., Reynolds, Christopher A., Simms, John, Walker, Christopher S., Mobarec, Juan Carlos, Garelja, Michael L., Conner, Alex C., Poyner, David R. and Hay, Debbie L. (2017). Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs. Biochemical Pharmacology, in pre ,

Woolley, Michael J., Simms, John, Mobarec, Juan Carlos, Reynolds, Christopher A., Poyner, David R. and Conner, Alex C. (2017). Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach. Molecular and Cellular Endocrinology, in pre ,

Routledge, Sarah J., Ladds, Graham and Poyner, David R. (2017). The effects of RAMPs upon cell signalling. Molecular and Cellular Endocrinology, in pre ,

Weston, Cathryn, Winfield, Ian, Harris, Matthew, Hodgson, Rose, Shah, Archna, Dowell, Simon J., Mobarec, Juan Carlos, Woodlock, David A., Reynolds, Christopher A., Poyner, David R., Watkins, Harriet A. and Ladds, Graham (2016). Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors. Journal of Biological Chemistry, 291 (42), pp. 21925-21944.

Watkins, Harriet A., Chakravarthy, Madhuri, Abhayawardana, Rekhati S., Gingell, Joseph J., Garelja, Michael, Pardamwar, Meenakshi, McElhinney, James M.W.R., Lathbridge, Alex, Constantine, Arran, Harris, Paul W.R., Yuen, Tsz-Ying, Brimble, Margaret A., Barwell, James, Poyner, David R., Woolley, Michael J., Conner, Alex C., Pioszak, Augen A., Reynolds, Christopher A. and Hay, Debbie L. (2016). Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties. Journal of Biological Chemistry, 291 (22), pp. 11657-11675.

Gingell, Joseph J., Simms, John, Barwell, James, Poyner, David R., Watkins, Harriet A., Pioszak, Augen A., Sexton, Patrick M. and Hay, Debbie L. (2016). An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology. Cell Discovery, 2 ,

Wheatley, Mark, Charlton, Jack, Jamshad, Mohammed, Routledge, Sarah J., Bailey, Sian, La-Borde, Penelope J., Azam, Maria T., Logan, Richard T., Bill, Roslyn M., Dafforn, Tim R. and Poyner, David R. (2016). GPCR-styrene maleic acid lipid particles (GPCR-SMALPs):their nature and potential. Biochemical Society Transactions, 44 (2), pp. 619-623.

Weston, Cathryn, Lu, Jing, Li, Naichang, Barkan, Kerry, Richards, Gareth O., Roberts, David J., Skerry, Timothy M., Poyner, David, Pardamwar, Meenakshi, Reynolds, Christopher A., Dowell, Simon J., Willars, Gary B. and Ladds, Graham (2015). Modulation of glucagon receptor pharmacology by Receptor Activity-modifying Protein-2 (RAMP2). Journal of Biological Chemistry, 290 (38), pp. 23009-23022.

Booe, Jason M., Walker, Christopher S., Barwell, James, Kuteyi, Gabriel, Simms, John, Jamaluddin, Muhammad A., Warner, Margaret L., Bill, Roslyn M., Harris, Paul W., Brimble, Margaret A., Poyner, David R., Hay, Debbie L. and Pioszak, Augen A. (2015). Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor. Molecular Cell, 58 (6), pp. 1040-1052.

Jamshad, Mohammed, Charlton, Jack, Lin, Yu-Pin, Routledge, Sarah J, Bawa, Zharain, Knowles, Timothy J., Overduin, Michael, Dekker, Niek, Dafforn, Tim R., Bill, Roslyn M., Poyner, David R. and Wheatley, Mark (2015). G-protein-coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent. Bioscience Reports, 35 (2),

Bawa, Zharain, Routledge, Sarah J., Jamshad, Mohammed, Clare, Michelle, Sarkar, Debasmita, Dickerson, Ian, Ganzlin, Markus, Poyner, David R. and Bill, Roslyn M. (2014). Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. Microbial Cell Factories, 13 (1),

Weston, C., Poyner, D., Patel, V., Dowell, S. and Ladds, G. (2014). Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast. British Journal of Pharmacology, 171 (15), pp. 3651-3665.

Watkins, H.A., Walker, C.S., Ly, K.N., Bailey, R.J., Barwell, J., Poyner, D.R. and Hay, D.L. (2014). Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor:implications for adrenomedullin and calcitonin gene-related peptide pharmacology. British Journal of Pharmacology, 171 (3), pp. 772-788.

Routledge, Sarah J., Poyner, David R. and Bill, Roslyn M. (2014). Antifoams:the overlooked additive? Pharmaceutical Bioprocessing, 2 (2), pp. 103-106.

Hay, Debbie L., Harris, Paul W.R., Kowalczyk, Renata, Brimble, Margaret A., Rathbone, Dan L, Barwell, James, Conner, Alex C. and Poyner, David R. (2014). Structure-activity relationships of the N-terminus of calcitonin gene-related peptide:key roles of alanine-5 and threonine-6 in receptor activation. British Journal of Pharmacology, 171 (2), pp. 415-426.

Woolley, Michael J., Watkins, Harriet A., Taddese, Bruck, Karakullukcu, Z. Gamze, Barwell, James, Smith, Kevin J., Hay, Debbie L., Poyner, David R., Reynolds, Christopher A. and Conner, Alex C. (2013). The role of ECL2 in CGRP receptor activation:a combined modelling and experimental approach. Journal of the Royal Society Interface, 10 (88),

Vohra, Shabana, Taddese, Bruck, Conner, Alex C., Poyner, David R., Hay, Debbie L., Barwell, James, Reeves, Philip J., Upton, Graham J.G. and Reynolds, Christopher A. (2013). Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies. Journal of the Royal Society Interface, 10 (79),

Hong, Yanguo, Hay, Debbie L., Quirion, Remi and Poyner, David R. (2012). The pharmacology of adrenomedullin 2/intermedin. British Journal of Pharmacology, 166 (1), pp. 110-120.

Wheatley, M., Wootten, Denise, Conner, Matthew T., Simms, John, Kendrick, R., Logan, R.T., Poyner, David R. and Barwell, James (2012). Lifting the lid on GPCRs:the role of extracellular loops. British Journal of Pharmacology, 165 (6), pp. 1688-1703.

Barwell, James, Conner, Alex C. and Poyner, David R (2011). Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function. BBA - Molecular Cell Research, 1813 (10), pp. 1906-1916.

Miller, Philip S., Barwell, James, Poyner, David R., Wigglesworth, Mark J., Garland, Stephen L. and Donnelly, Dan (2010). Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74. Biochemical and Biophysical Research Communications, 391 (1), pp. 437-442.

Barwell, James, Miller, Philip S., Donnelly, Dan and Poyner, David R. (2010). Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor. Peptides, 31 (1), pp. 170-176.

Bonander, Nicklas, Darby, Richard A.J., Grgic, Ljuban, Bora, Nagamani, Wen, Jikai, Brogna, Saverio, Poyner, David R., O'Neill, Michael A. A. and Bill, Roslyn M. (2009). Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield. Microbial Cell Factories, 8 (10),

Conner, Alex C., Simms, John, Howitt, Stephen G., Wheatley, Mark and Poyner, David R. (2006). The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression. Journal of Biological Chemistry, 281 (3), pp. 1644-1651.

Lattmann, Eric, Billington, David C., Poyner, David R., Arayarat, Pornthip, Howitt, Stephen B., Lawrence, Spencer and Offel, Michael (2002). Combinatorial solid phase synthesis of multiply substituted 1,4-benzodiazepines and affinity studies on the CCK2 receptor (Part 1). Drug Design and Discovery, 18 (1), pp. 9-21.

Hay, Debbie L., Howitt, Stephen G., Conner, Alex C., Doods, Henri, Schindler, Marcus and Poyner, David R. (2002). A comparison of the actions of BIBN4096BS and CGRP 8-37 on CGRP and adrenomedullin receptors expressed on SK-N-MC, L6, Col 29 and Rat 2 cells. British Journal of Pharmacology, 137 (1), pp. 80-86.

Akhtar, Saghir, Dunnion, Debbie, Poyner, David, Ackroyd, John, Bibby, Mike and Double, John (2002). Sequence and chemistry requirements for a novel aptameric oligonucleotide inhibitor of EGF receptor tyrosine kinase activity. Biochemical Pharmacology, 63 (12), pp. 2187-2195.

Lattmann, Eric, Billington, David C., Poyner, David, Howitt, Stephen B. and Offel, Michael (2001). Synthesis and evaluation of asperlicin analogues as non-peptidal cholecystokinin-antagonists. Drug Design and Discovery, 17 (3), pp. 219-230.

Conner, Alex C. and Poyner, David R. (2001). The perils of using the human genome sequence:Lessons from CALCRL. Trends in Pharmacological Sciences, 22 (6), p. 272.

Gosling, M., Poyner, David and Smith, J.W. (1996). Effects of arachidonic acid upon the volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Journal of Physiology, 493 (3), pp. 613-623.

Tomlinson, A. Elaine and Poyner, David (1996). Multiple receptors for calcitonin gene-related peptide and amylin on guinea-pig ileum and vas deferens. British Journal of Pharmacology, 117 (6), pp. 1362-1368.

Hawkins, Phillip T., Poyner, David R., Jackson, T.R., Letcher, A.J., Lander, Dawn and Irvine, R.F. (1993). Inhibition of iron-catalysed hydroxyl radical formation by inositol polyphosphates: a possible physiological function for myo-inositol hexakisphosphate. Biochemical Journal, 294 , pp. 929-934.

Poyner, David R., Cooke, F., Hanley, Michael R., Reynolds, D.J. and Hawkins, Phillip T. (1993). Characterization of metal ion-induced [3H]inositol hexakisphosphate binding to rat cerebellar membranes. Journal of Biological Chemistry, 268 (2), pp. 1032-1038.

Poyner, David R., Hawkins, Phillip T., Benton, H.P. and Hanley, Michael R. (1990). Changes in inositol lipids and phosphates after stimulation of the MAS-transfected NG115-401L-C3 cell line by mitogenic and non-mitogenic stimuli. Biochemical Journal, 271 (3), pp. 605-611.

This list was generated on Wed Jul 24 01:55:49 2019 BST.