Browse by Aston Author

2023

Mulla, Suhayl, Ludlam, Adele R., Elragig, Aiman, Slack, Cathy, Balklava, Zita, Stich, Michael and Cheong, Alex (2023). A biphasic model of lifespan in nematode Caenorhabditis elegans worm. Royal Society Open Science, 10 (2), p. 220991.

2022

Laskovs, Mihails, Partridge, Linda and Slack, Cathy (2022). Molecular inhibition of RAS signalling to target ageing and age-related health. Disease Models & Mechanisms, 15 (10),

2021

Chen, Zhengqi, Cordero, Julia, Alqarni, Adel M, Slack, Cathy, Zeidler, Martin P and Bellantuono, Ilaria (2021). Zoledronate extends healthspan and survival via the mevalonate pathway in a FOXO-dependent manner. Journals of Gerontology: Series A ,

2020

Wiseman, Daniel N., Otchere, Abigail, Patel, Jaimin H., Uddin, Romez, Pollock, Naomi L., Routledge, Sarah J., Rothnie, Alice J., Slack, Cathy, Poyner, David R., Bill, Roslyn M. and Goddard, Alan D. (2020). Expression and purification of recombinant G protein-coupled receptors: A review. Protein Expression and Purification, 167 ,

2017

Slack, Cathy (2017). Ras signaling in aging and metabolic regulation. Nutrition and Healthy Aging, 4 (3), pp. 195-205.

2016

Castillo-Quan, Jorge Iván, Li, Li, Kinghorn, Kerri J., Ivanov, Dobril K., Tain, Luke S., Slack, Cathy, Kerr, Fiona, Nespital, Tobias, Thornton, Janet, Hardy, John, Bjedov, Ivana and Partridge, Linda (2016). Lithium promotes longevity through GSK3/NRF2-dependent hormesis. Cell Reports, 15 (3), pp. 638-650.

2015

Slack, Cathy, Alic, Nazif, Foley, Andrea, Cabecinha, Melissa, Hoddinott, Matthew P. and Partridge, Linda (2015). The Ras-Erk-ETS-signaling pathway is a drug target for longevity. Cell, 162 (1), pp. 72-83.

2014

Alic, Nazif, Tullet, Jennifer M., Niccoli, Teresa, Broughton, Susan, Hoddinott, Matthew P., Slack, Cathy, Gems, David and Partridge, Linda (2014). Cell-nonautonomous effects of dFOXO/DAF-16 in aging. Cell Reports, 6 (4), pp. 608-616.

2012

Slack, Cathy, Foley, Andrea and Partridge, Linda (2012). Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in drosophila. PLoS ONE, 7 (10),

Alic, Nazif, Hoddinott, Matthew P., Foley, Andrea, Slack, Cathy, Piper, Matthew D.W. and Partridge, Linda (2012). Detrimental effects of RNAi:a cautionary note on its use in drosophila ageing studies. PLoS ONE, 7 (9),

2011

Slack, Cathy, Giannakou, Maria E., Foley, Andrea, Goss, Martin and Partridge, Linda (2011). dFOXO-independent effects of reduced insulin-like signaling in drosophila. Aging Cell, 10 (5), pp. 735-748.

Wigby, Stuart, Slack, Cathy, Grönke, Sebastian, Martinez, Pedro, Calboli, Federico C.F., Chapman, Tracey and Partridge, Linda (2011). Insulin signalling regulates remating in female drosophila. Proceeding of the Royal Society: Series B, 278 (1704), pp. 424-431.

Alic, Nazif, Andrews, T. Daniel, Giannakou, Maria E., Papatheodorou, Irene, Slack, Cathy, Hoddinott, Matthew P., Cochemé, Helena M., Schuster, Eugene F., Thornton, Janet M. and Partridge, Linda (2011). Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling. Molecular Systems Biology, 7 (1),

2010

Slack, Cathy, Werz, Christian, Wieser, Daniela, Alic, Nazif, Foley, Andrea, Stocker, Hugo, Withers, Dominic J., Thornton, Janet M., Hafen, Ernst and Partridge, Linda (2010). Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. PLoS Genetics, 6 (3),

Bjedov, Ivana, Toivonen, Janne M., Kerr, Fiona, Slack, Cathy, Jacobson, Jake, Foley, Andrea and Partridge, Linda (2010). Mechanisms of life span extension by rapamycin in the fruit fly drosophila melanogaster. Cell metabolism, 11 (1), pp. 35-46.

2008

Broughton, Susan, Alic, Nazif, Slack, Cathy, Bass, Timothy, Ikeya, Tomoatsu, Vinti, Giovanna, Tommasi, Anna Maria, Driege, Yasmine, Hafen, Ernst and Partridge, Linda (2008). Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS ONE, 3 (11),

2007

Slack, Cathy, Overton, Paul M., Tuxworth, Richard I. and Chia, William (2007). Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome. Development, 134 (21), pp. 3781-3787.

2006

Slack, Cathy, Somers, W. Gregory, Sousa-Nunes, Rita, Chia, William and Overton, Paul M. (2006). A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions. Genetics, 7 ,