Browse by Aston Author

Chen, Xianfeng; Liu, Chen; Cardoso, Marcos R.; Mendonça, Cleber R.; Nagel, David A.; Hine, Anna V. and Zhang, Lin (2016). Label-free oligonucleotide biosensor based on dual-peak long period fiber grating. IN: Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI. Gannot, Israel (ed.) SPIE Proceedings . Bellingham, WA (US): SPIE.

Chen, Xianfeng; Liu, Chen; Hughes, Marcus D.; Nagel, David A.; Hine, Anna V. and Zhang, Lin (2015). EDC-mediated oligonucleotide immobilization on a long period grating optical biosensor. Journal of Biosensors and Bioelectronics, 6 (2),

Hine, Anna V.; Ashraf, Mohammed; Frigotto, Laura; Smith, Matthew E.; Patel, Seema; Hughes, Marcus D.; Poole, Andrew J.; Hebaishi, Husam R.M. and Ullman, Christopher G. (2013). ProxiMAX randomisation:a new technology for non-degenerate saturation mutagenesis of contiguous codons. IN: Protein engineering: new approaches and applications. University of Chester, 2013-04-10 - 2013-04-12.

Poole, Andrew J.; Ullman, Christopher G. and Hine, Anna V. (2013). The integration of ProxiMAX randomisation with CIS display for the high-throughput production of novel peptides. IN: Protein engineering: new approaches and applications. University of Chester, 2013-04-10 - 2013-04-12.

Behrendt, Jonathan M.; Nagel, David; Chundoo, Evita; Alexander, Lois M.; Dupin, Damien; Hine, Anna V.; Bradley, Mark and Sutherland, Andrew J. (2013). Synthesis and characterization of dual-functionalized core-shell fluorescent microspheres for bioconjugation and cellular delivery. PLoS ONE, 8 (3),

Chen, Xianfeng F.; Hughes, Marcus D.; Zhou, Kaiming; Davies, Edward; Zhang, Lin; Hine, Anna V. and Bennion, Ian (2007). Long-period fibre grating based biosensor for detection of DNA hybridisation. IN: Bragg Gratings, Photosensitivity, and Poling in Glass Waveguides, OSA Technical Digest (CD). Optical Society of America.

Chen, Xianfeng F.; Zhang, Lin; Zhou, Kaiming; Davies, Edward; Sugden, Kate; Bennion, Ian; Hughes, Marcus D. and Hine, Anna V. (2007). Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. Optics letters, 32 (17), pp. 2541-2543.

Forde, Gareth M.; Ghose, Siddhartha; Slater, Nigel K. H.; Hine, Anna V.; Darby, Richard A.J. and Hitchcock, Anthony G. (2006). LacO-LacI interaction in affinity adsorption of plasmid DNA. Biotechnology and Bioengineering, 95 (1), pp. 67-75.

McCairn, Mark C.; Hughes, Marcus D.; Hine, Anna V. and Sutherland, Andrew (2006). Solid-phase PNA synthesis and in situ scintillation proximity assay for the detection of PNA-DNA hybridization. Journal of Combinatorial Chemistry, 8 (1), pp. 1-3.

Hughes, Marcus D.; Zhang, Zhan-Ren; Sutherland, Andrew; Santos, Albert F. and Hine, Anna V. (2005). Discovery of active proteins directly from combinatorial randomized protein libraries without display, purification or sequencing:identification of novel zinc finger proteins. Nucleic Acids Research, 33 (3),

Hine, Anna V.; Hughes, Marcus D.; Zhang, Zhan-Ren; Nagel, David A.; Ashraf, M. and Santos, Albert F. (2002). Combinatorial gene libraries and high-throughput screening for rapid protein engineering. Abstracts of Papers of the American Chemical Society, 224 (1), U252-U252.

Palfrey, David; Cook, P.J.; Smythe, J.A.; Lip, G.Y. and Hine, Anna V. (1999). Simplified preparation of human arterial sections for PCR analysis of Chlamydia pneumoniae and human DNA. Molecular Pathology, 52 (5), pp. 289-294.

Hine, Anna V. and Richardson, Charles C. (1994). A functional chimeric DNA primase: the Cys4 zinc-binding domain of bacteriophage T3 primase fused to the helicase of bacteriophage T7. Proceedings of the National Academy of Sciences, 91 (25), pp. 12327-12331.

Hine, Anna V. and Brown, Terence A. (1994). Synthesis and expression of a gene encoding a 48-residue repeat in the Pseudomonas syringae ice nucleation protein. Gene, 142 (1), pp. 73-78.

Darby, Richard A.J.; Forde, Gareth M.; Slater, Nigel K. H. and Hine, Anna V. Affinity purification of plasmid DNA directly from crude bacterial cell lysates. Biotechnology and Bioengineering, 98 (5), pp. 1103-1108.

Darby, Richard A.J.; Slater, Nigel K. H. and Hine, Anna V. Affinity-based isolation of plasmid DNA. Abstracts of Papers of the American Chemical Society, 224 (1), U240-U240.

Frigotto, Laura; Smith, Matthew E.; Brankin, Christopher; Sedani, Ashni; Cooper, Simon E.; Kanwar, Nisha; Evans, Daniel; Svobodova, Stanislava; Baar, Claudia; Glanville, Jacob; Ullman, Christopher G. and Hine, Anna V. Codon-precise, synthetic, antibody fragment libraries built using automated hexamer codon additions and validated through next generation sequencing. Antibodies, 4 (2), pp. 88-102.

Kusakabe, Takahiro; Hine, Anna V.; Hyberts, Sven G. and Richardson, Charles C. The Cys4 zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition. Proceedings of the National Academy of Sciences, 96 (8), pp. 4295-4300.

Hughes, Marcus D.; Nagel, David A. and Hine, Anna V. Efficient gene randomisation for generation of protein libraries. Abstracts of Papers of the American Chemical Society, 224 (1), U230-U231.

Khal, J.; Wyke, S.M.; Russell, Steve T.; Hine, Anna V. and Tisdale, Michael J. Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia. British Journal of Cancer, 93 (7), pp. 774-780.

Zhang, Zhan-Ren; Palfrey, David; Nagel, David A.; Lambert, Peter A.; Jessop, Robert A.; Santos, Albert F. and Hine, Anna V. Fluorescent microplate-based analysis of protein-DNA interactions I:immobilized protein. Biotechniques, 35 (5), pp. 980-986.

Zhang, Zhan-Ren; Hughes, Marcus D.; Morgan, Leonie J.; Santos, Albert F. and Hine, Anna V. Fluorescent microplate-based analysis of protein-DNA interactions II:immobilized DNA. Biotechniques, 35 (5), pp. 988-996.

Darby, Richard A.J. and Hine, Anna V. LacI-mediated sequence-specific affinity purification of plasmid DNA for therapeutic applications. FASEB Journal, 19 (7), pp. 801-803.

Chen, Xianfeng F.; Hughes, Marcus D.; Zhou, Kaiming; Davies, Edward; Zhang, Lin; Hine, Anna V. and Bennion, Ian Long-period fibre grating based biosensor for detection of DNA hybridisation. IN: Bragg Gratings, Photosensitivity, and Poling in Glass Waveguides, OSA Technical Digest (CD). Optical Society of America.

Hine, Anna V.; Chen, Xianfeng F.; Hughes, Marcus D.; Zhou, Kaiming; Davies, Edward; Sugden, Kate; Bennion, Ian and Zhang, Lin Optical fibre-based detection of DNA hybridization. Biochemical Society Transactions, 37 (Part 2), pp. 445-449.

Nagel, David; Behrendt, Jonathan M.; Chimonides, Gwen F.; Torr, Elizabeth E.; Devitt, Andrew; Sutherland, Andy J. and Hine, Anna V. Polymeric microspheres as protein transduction reagents. Molecular and Cellular Proteomics, 13 (6), pp. 1543-1551.

Woodgate, John; Palfrey, David; Nagel, David; Hine, Anna V. and Slater, Nigel K.H. Protein-mediated isolation of plasmid DNA by a zinc finger-glutathione S-transferase affinity linker. Biotechnology and Bioengineering, 79 (4), pp. 450-456.

Ashraf, Mohammed; Frigotto, Laura; Smith, Matthew E.; Patel, Seema; Hughes, Marcus D.; Poole, Andrew J.; Hebaishi, Husam R.M.; Ullman, Christopher G. and Hine, Anna V. ProxiMAX randomisation:a new technology for non-degenerate saturation mutagenesis of contiguous codons. Biochemical Society Transactions, 41 (5), pp. 1189-1194.

Chen, Xianfeng; Zhang, Lin; Zhou, Kaiming; Davies, Edward; Sugden, Kate; Bennion, Ian; Hughes, Marcus D. and Hine, Anna V. Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. Optics Letters, 32 (17), pp. 2541-2543.

Allsop, Thomas D.P.; Mou, Chengbo; Neal, Ron; Mariani, Stefano; Nagel, David; Tombelli, Sara; Poole, Andrew; Kalli, Kyriacos; Hine, Anna V.; Webb, David J.; Culverhouse, Philip; Mascini, M.; Minunni, Maria and Bennion, Ian Real-time kinetic binding studies at attomolar concentrations in solution phase using a single-stage opto-biosensing platform based upon infrared surface plasmons. Optics Express, 25 (1), pp. 39-58.

Hughes, Marcus D.; Nagel, David A.; Santos, Albert F.; Sutherland, Andrew J. and Hine, Anna V. Removing the redundancy from randomised gene libraries. Journal of Molecular Biology, 331 (5), pp. 973-979.

McCairn, Mark C.; Hine, Anna V. and Sutherland, Andrew J. Synthesis and evaluation of scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports. Journal of Materials Chemistry, 13 (2), pp. 225-231.

Behrendt, Jonathan H.; Afzaal, Mohammad; Alexander, Lois M.; Bradley, Mark; Hine, Anna V.; Nagel, David A.; O'Brien, Paul; Presland, Katayune and Sutherland, Andrew J. Thiol-containing microspheres as polymeric ligands for the immobilisation of quantum dots. Journal of Materials Chemistry, 19 (2), pp. 215-221.

Palfrey, David; Picardo, M. and Hine, Anna V. A new randomization assay reveals Unexpected elements of sequence bias in model 'randomized' gene libraries:Implications for biopanning. Gene, 251 (1), pp. 91-99.

McCairn, Mark C.; Hughes, Marcus D.; Hine, Anna V. and Sutherland, Andrew A platform for both solid-phase peptide nucleic acid oligomer synthesis and subsequent in situ detection and quantification of nucleic acid sequences. Journal of Combinatorial Chemistry, 8 (5), pp. 639-642.