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Skipworth, Richard J.E.; Stephens, Nathan A.; Johns, Neil; Guttridge, Denis C.; Tisdale, Michael J.; Baracos, Vickie E. and Glass, David J. (2016). Ken Fearon:obituary. Cell metabolism, 24 (6), pp. 765-766.

Mirza, Kamran A.; Luo, Menghua; Pereira, Suzette; Voss, Anne; Das, Tapas and Tisdale, Michael J. (2016). In vitro assessment of the combined effect of eicosapentaenoic acid, green tea extract and curcumin C3 on protein loss in C2C12 myotubes. In Vitro Cellular and Developmental Biology: Animal, 52 (8), 838–845.

Mirza, Kamran A.; Pereira, Suzette L.; Voss, Anne C. and Tisdale, Michael J. (2014). Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate in experimental models of cancer cachexia. Nutrition, 30 (7-8), pp. 807-813.

Russell, Steven T. and Tisdale, Michael J. (2012). Role of β-adrenergic receptors in the oral activity of zinc-α2-glycoprotein (ZAG). Endocrinology, 153 (10), pp. 4696-4704.

Russell, Steven T. and Tisdale, Michael J. (2012). Role of β-adrenergic receptors in the anti-obesity and anti-diabetic effects of zinc-α2-glycoprotien (ZAG). BBA - Molecular and Cell Biology of Lipids, 1821 (4), pp. 590-599.

Russell, Steven T.; Siren, Pontus M.A.; Siren, Matti J. and Tisdale, Michael J. (2010). Mechanism of attenuation of protein loss in murine C2C12 myotubes by d-myo-inositol 1,2,6-triphosphate. Experimental Cell Research, 316 (2), pp. 286-295.

Russell, Steven T. and Tisdale, Michael J. (2009). Mechanism of attenuation by β-hydroxy-β-methylbutyrate of muscle protein degradation induced by lipopolysaccharide. Molecular and Cellular Biochemistry, 330 (1-2), pp. 171-179.

Russell, Steve T.; Siren, P.M.A.; Siren, M.J. and Tisdale, Michael J. (2009). Attenuation of skeletal muscle atrophy in cancer cachexia by d-myo-inositol 1,2,6-triphosphate. Cancer Chemotherapy and Pharmacology, 64 (3), pp. 517-527.

Eley, Helen L.; McDonald, Pria S.; Russell, Steve T. and Tisdale, Michael J. (2009). Inhibition of activation of dsRNA-dependent protein kinase and tumour growth inhibition. Cancer Chemotherapy and Pharmacology, 63 (4), pp. 651-659.

Russell, Steve T.; Rajani, Seema; Dhadda, Raj S. and Tisdale, Michael J. (2009). Mechanism of induction of muscle protein loss by hyperglycaemia. Experimental Cell Research, 315 (1), pp. 16-25.

Eley, Helen L.; Russell, Steve T and Tisdale, Michael J. (2008). Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by beta-hydroxy-beta-methylbutyrate. American Journal of Physiology, 295 (6), E1409-E1416.

Eley, Helen L.; Russell, Steve T. and Tisdale, Michael J. (2008). Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by beta-hydroxy-beta-methylbutyrate. American Journal of Physiology, 295 (6), E1417-E1426.

Eley, H.L.; Russell, Steve T. and Tisdale, Michael J. (2008). Role of the dsRNA-dependent protein kinase (PKR) in the attenuation of protein loss from muscle by insulin and insulin-like growth factor-I (IGF-I). Molecular and Cellular Biochemistry, 313 (1-2), pp. 63-69.

Russell, Steve T.; Eley, Helen L.; Wyke, Stacey M. and Tisdale, Michael J. (2008). Involvement of phosphoinositide 3-kinase and Akt in the induction of muscle protein degradation by proteolysis-inducing factor. Biochemical Journal, 409 (Part 3), pp. 751-759.

Yano, Claudia L.; Ventrucci, Gislaine; Field, William N.; Tisdale, Michael J. and Gomes-Marcondes, Maria Cristina C. (2008). Metabolic and morphological alterations induced by proteolysis-inducing factor from Walker tumour-bearing rats in C2C12 myotubes. BMC Cancer, 8 (24), 24-.

Todorov, Penio T.; Wyke, Stacey M. and Tisdale, Michael J. (2007). Identification and characterization of a membrane receptor for proteolysis-inducing factor on skeletal muscle. Cancer Research, 67 (23), pp. 11419-11427.

Eley, Helen L.; Russell, Steven T.; Baxter, Jeffrey H.; Mukerji, Pradip and Tisdale, Michael J. (2007). Signaling pathways initiated by β-hydroxy-β-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli. American Journal of Physiology, 293 (4), pp. 923-931.

Russell, Steve T.; Eley, Helen and Tisdale, Michael J. (2007). Mechanism of attenuation of angiotensin-II-induced protein degradation by insulin-like growth factor-I (IGF-I). Cellular Signalling, 19 (7), pp. 1583-1595.

Tisdale, Michael J. (2007). Letter to the editor: eicosapentaenoic acid containing nutritional supplements for the treatment of cancer cachexia:Eicosapentaenoic acid containing nutritional supplements for the treatment of cancer cachexia. Clinical Nutrition, 26 (1), pp. 161-162.

Fearon, Kenneth C.H.; Barber, Matthew D.; Moses, Alastair G.; Ahmedzai, Sam H.; Taylor, Gillian S.; Tisdale, Michael J. and Murray, Gordon D. (2006). Double-blind, placebo-controlled, randomized study of eicosapentaenoic acid diester in patients with cancer cachexia. Journal of clinical oncology, 24 (21), pp. 3401-3407.

Chand, Anita; Wyke, Stacey M. and Tisdale, Michael J. (2005). Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle. Cancer Letters, 218 (2), pp. 215-222.

Smith, Helen J.; Wyke, Stacey M. and Tisdale, Michael J. (2004). Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by β-hydroxy-β-methylbutyrate. Cancer Research, 64 (23), pp. 8731-8735.

Sanders, Paul M. and Tisdale, Michael J. (2004). Effect of zinc-alpha 2-glycoprotein (ZAG) on expression of uncoupling proteins in skeletal muscle and adipose tissue. Cancer Letters, 212 (1), pp. 71-81.

Smith, Helen J.; Greenberg, N.A. and Tisdale, Michael J. (2004). Effect of eicosapentaenoic acid, protein and amino acids on protein synthesis and degradation in skeletal muscle of cachectic mice. British Journal of Cancer, 91 (2), pp. 408-412.

Bing, Chen; Bao, Yi; Jenkins, John; Sanders, Paul; Manieri, Monia; Cinti, Saverio; Tisdale, Michael J. and Trayhurn, Paul (2004). Zinc-α2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia. Proceedings of the National Academy of Sciences, 101 (8), pp. 2500-2505.

Smith, Helen J. and Tisdale, Michael J. (2003). Signal transduction pathways involved in proteolysis-inducing factor induced proteasome expression in murine myotubes. British Journal of Cancer, 89 (9), pp. 1783-1788.

Fearon, K.C.H.; von Meyenfeldt, M.F.; Moses, A.G.W.; van Geenen, R.; Roy, A.; Gouma, D.J.; Giacosa, A.; Van Gossum, A.; Bauer, J.; Barber, M.D.; Aaronson, N.K.; Voss, A.C. and Tisdale, Michael J. (2003). Effect of a protein and energy dense n-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia:A randomised double blind trial. Gut, 52 (10), pp. 1479-1486.

Whitehouse, A.S. and Tisdale, Michael J. (2003). Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappa B. British Journal of Cancer, 89 (6), pp. 1116-1122.

Whitehouse, A.S.; Khal, J. and Tisdale, Michael J. (2003). Induction of protein catabolism in myotubes by 15(S)-hydroxyeicosatetraenoic acid through increased expression of the ubiquitin-proteasome pathway. British Journal of Cancer, 89 (4), pp. 737-745.

Simpson, Julie; Forrester, Rebecca; Tisdale, Michael J.; Billington, David C. and Rathbone, Daniel L. (2003). Effect of catechol derivatives on cell growth and lipoxygenase activity. Bioorganic and Medicinal Chemistry Letters, 13 (15), pp. 2435-2439.

Wang, Zejing; Corey, Eva; Hass, G. Michael; Higano, Celestia S.; True, Lawrence D.; Wallace, David; Tisdale, Michael J. and Vessella, Robert L. (2003). Expression of the human cachexia-associated protein (HCAP) in prostate cancer and in a prostate cancer animal model of cachexia. International Journal of Cancer, 105 (1), pp. 123-129.

Tisdale, Michael J. (2003). The 'cancer cachectic factor'. Supportive care in cancer, 11 (2), pp. 73-78.

Tisdale, Michael J. (2002). Cachexia in cancer patients. Nature Reviews: Cancer, 2 (11), pp. 862-871.

Gomez-Ambrosi, J.; Zabalegui, N.; Bing, C.; Tisdale, Michael J.; Trayhurn, P. and Williams, G. (2002). Weight loss in tumour-bearing mice is not associated with changes in resistin gene expression in white adipose tissue. Hormone and Metabolic Research, 34 (11-12), pp. 674-677.

Gomes-Marcondes, Maria Cristina C. and Tisdale, Michael J. (2002). Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress. Cancer Letters, 180 (1), pp. 69-74.

Gomes-Marcondes, Maria C.C.; Smith, Helen J.; Cooper, J.C. and Tisdale, Michael J. (2002). Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factor. British Journal of Cancer, 86 (10), pp. 1628-1633.

Bing, C.; Taylor, S.; Tisdale, Michael J. and Williams, G. (2001). Cachexia in MAC16 adenocarcinoma:Suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y. Journal of Neurochemistry, 79 (5), pp. 1004-1012.

Whitehouse, A.S. and Tisdale, Michael J. (2001). Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation. Biochemical and Biophysical Research Communications, 285 (3), pp. 598-602.

Islam-Ali, B.; Khan, S.; Price, S.A. and Tisdale, Michael J. (2001). Modulation of adipocyte G-protein expression in cancer cachexia by a lipid-mobilizing factor (LMF). British Journal of Cancer, 85 (5), pp. 758-763.

Islam-Ali, B.S. and Tisdale, Michael J. (2001). Effect of a tumour-produced lipid-mobilizing factor on protein synthesis and degradation. British Journal of Cancer, 84 (12), pp. 1648-1655.

Whitehouse, A.S.; Smith, Helen J.; Drake, J.L. and Tisdale, Michael J. (2001). Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid. Cancer Research, 61 (9), pp. 3604-3609.

Barber, Matthew D.; Fearon, Kenneth C.H.; Tisdale, Michael J.; McMillan, Donald C. and Ross, James A. (2001). Effect of a fish oil-enriched nutritional supplement on metabolic mediators in patients with pancreatic cancer cachexia. Nutrition and Cancer, 40 (2), pp. 118-124.

Lorite, M.J.; Smith, Helen J.; Arnold, J.A.; Morris, A.; Thompson, M.G. and Tisdale, Michael J. Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF). British Journal of Cancer, 85 (2), pp. 297-302.

Russell, Steve T.; Sanders, Paul M. and Tisdale, Michael J. Angiotensin II directly inhibits protein synthesis in murine myotubes. Cancer Letters, 231 (2), pp. 290-294.

Russell, Steve T. and Tisdale, Michael J. Antidiabetic properties of zinc-alpha2-glycoprotein in ob/ob mice. Endocrinology, 151 (3), pp. 948-957.

Tisdale, Michael J. Are tumoral factors responsible for host tissue wasting in cancer cachexia? Future Oncology, 6 (4), pp. 503-513.

Mirza, Kamran A.; Pereira, Suzette L.; Edens, Neile K. and Tisdale, Michael J. Attenuation of muscle wasting in murine C2C12myotubes by epigallocatechin-3-gallate. Journal of Cachexia, Sarcopenia and Muscle, 5 (4), pp. 339-345.

Smith, Helen J.; Mukerji, Pradip and Tisdale, Michael J. Attenuation of proteasome-induced proteolysis in skeletal muscle by beta-hydroxy-beta-methylbutyrate in cancer-induced muscle loss. Cancer Research, 65 (1), pp. 277-283.

Tisdale, Michael J. Biochemical mechanisms of cellular catabolism. Current Opinion in Clinical Nutrition and Metabolic Care, 5 (4), pp. 401-405.

Tisdale, Michael J. Cancer cachexia. Langenbeck's Archive of Surgery, 389 (4), pp. 299-305.

Tisdale, Michael J. Cancer cachexia. Current Opinion in Gastroenterology, 26 (2), pp. 146-151.

Bhogal, Ameek S.; Lorite, Maria L. and Tisdale, Michael J. Changes in nucleic acid and protein levels in atrophying skeletal muscle in cancer cachexia. Anticancer Research, 26 (6B), pp. 4149-4154.

Belizario, J.E.; Lorite, M.J. and Tisdale, Michael J. Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia. British Journal of Cancer, 84 (8), pp. 1135-1140.

Tisdale, Michael J. Clinical anticachexia treatments. Nutrition in Clinical Practice, 21 (2), pp. 168-174.

Lattmann, Eric; Kinchington, Derek; Dunn, Simon; Singh, Harjit; Ayuko, Washington O. and Tisdale, Michael J. Cytotoxicity of 3,4-dihalogenated 2(5H)-furanones. Journal of Pharmacy and Pharmacology, 56 (9), pp. 1163-1170.

Khal, Jwan and Tisdale, Michael J. Downregulation of muscle protein degradation in sepsis by eicosapentaenoic acid (EPA). Biochemical and Biophysical Research Communications, 375 (2), pp. 238-240.

Smith, Helen J.; Khal, Jwan and Tisdale, Michael J. Downregulation of ubiquitin-dependent protein degradation in murine myotubes during hyperthermia by eicosapentaenoic acid. Biochemical and Biophysical Research Communications, 332 (1), pp. 83-88.

Eley, Helen L.; Russell, Steve T. and Tisdale, Michael J. Effect of branched-chain amino acids on muscle atrophy in cancer cachexia. Biochemical Journal, 407 (1), pp. 113-120.

Wynter, Michael P.; Russell, Steve T. and Tisdale, Michael J. Effect of n-3 fatty acids on the antitumour effects of cytotoxic drugs. In Vivo, 18 (5), pp. 543-548.

Deans, D.A.C.; Wigmore, S.J.; Gilmour, H.; Tisdale, Michael J.; Fearon, Kenneth C.H. and Ross, J.A. Expression of the proteolysis-inducing factor core peptide mRNA is upregulated in both tumour and adjacent normal tissue in gastro-oesophageal malignancy. British Journal of Cancer, 94 (5), pp. 731-736.

Khal, J.; Wyke, S.M.; Russell, Steve T.; Hine, Anna V. and Tisdale, Michael J. Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia. British Journal of Cancer, 93 (7), pp. 774-780.

Eley, H.L.; Skipworth, R.J.E.; Deans, D.A.C.; Fearon, K.C.H. and Tisdale, Michael J. Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2 alpha may signal skeletal muscle atrophy in weight-losing cancer patients. British Journal of Cancer, 98 (2), pp. 443-449.

Russell, Steve T.; Zimmerman, Thomas P.; Domin, Barbara A. and Tisdale, Michael J. Induction of lipolysis in vitro and loss of body fat in vivo by zinc-α2-glycoprotein. BBA - Molecular and Cell Biology of Lipids, 1636 (1), pp. 59-68.

Wyke, S.M.; Russell, Steve T. and Tisdale, Michael J. Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-κB activation. British Journal of Cancer, 91 (9), pp. 1742-1750.

Tisdale, Michael J. Loss of skeletal muscle in cancer:biochemical mechanisms. Frontiers in Bioscience, 6 , D164-D174.

Russell, Steve T.; Wyke, Stacey M. and Tisdale, Michael J. Mechanism of induction of muscle protein degradation by angiotensin II. Cellular Signalling, 18 (7), pp. 1087-1096.

Tisdale, Michael J. Mechanisms of Cancer Cachexia. Physiological Reviews, 89 (2), pp. 381-410.

Tisdale, Michael J. Molecular pathways leading to cancer cachexia. Physiology, 20 (5), pp. 340-348.

Wyke, Stacey M. and Tisdale, Michael J. NF-κB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle. British Journal of Cancer, 92 (4), pp. 711-721.

Tisdale, Michael J. Re: Wieland BM, et al. is there a human homologue to the murine proteolysis - inducing factor? Clinical Cancer Research, 14 (7), p. 2245.

Tisdale, Michael J. Reversing cachexia. Cell, 142 (4), pp. 511-512.

Sanders, P.M. and Tisdale, Michael J. Role of lipid-mobilising factor (LMF) in protecting tumour cells from oxidative damage. British Journal of Cancer, 90 (6), pp. 1274-1278.

Smith, Helen J.; Wyke, S.M. and Tisdale, Michael J. Role of protein kinase C and NF-kappa B in proteolysis-inducing factor-induced proteasome expression in C2C12 myotubes. British Journal of Cancer, 90 (9), pp. 1850-1857.

Russell, Steve T.; Hirai, K. and Tisdale, Michael J. Role of β3-adrenergic receptors in the action of a tumour lipid mobilizing factor. British Journal of Cancer, 86 (3), pp. 424-428.

Eley, Helen L.; Russell, Steve T.; Baxter, Jeffrey H.; Mukerji, Pradip and Tisdale, Michael J. Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli. American Journal of Physiology, 293 (4), E923-E931.

Eley, Helen L. and Tisdale, Michael J. Skeletal muscle atrophy, a link between depression of protein synthesis and increase in degradation. Journal of Biological Chemistry, 282 (10), pp. 7087-7097.

Lattmann, Eric; Ayuko, Washington O.; Kinchinaton, Derek; Langley, Chris A.; Singh, Harjit; Karimi, Leila and Tisdale, Michael J. Synthesis and evaluation of 5-arylated 2(5H)-furanones and 2-arylated pyridazin-3(2H)-ones as anti-cancer agents. Journal of Pharmacy and Pharmacology, 55 (9), pp. 1259-1265.

Tisdale, Michael J. Tumor-host interactions. Journal of Cellular Biochemistry, 93 (5), pp. 871-877.

Tisdale, Michael J. Zinc-α2-glycoprotein in cachexia and obesity. Current Opinion in Supportive and Palliative Care, 3 (4), pp. 288-293.

Russell, Steve T. and Tisdale, Michael J. The role of glucocorticoids in the induction of zinc-α2-glycoprotein expression in adipose tissue in cancer cachexia. British Journal of Cancer, 92 (5), pp. 876-881.

Book Section

Tisdale, Michael J. Catabolism of skeletal muscle proteins and its reversal in cancer cachexia. IN: Cancer and nutrition. Mason, J. and Nitenberg, G. (eds) Nestle nutiotion workshop series: clinical and performance program, 4 . Basel (CH): Karger.