Browse by Aston Author

Litvinova, Karina S.; Ahmad, Shakil; Wang, Keqing; Rafailov, Ilya E.; Sokolovski, Sergei G.; Zhang, Lin; Rafailov, Edik U. and Ahmed, Asif (2016). A pilot study using laser-based technique for non-invasive diagnostics of hypertensive conditions in mice. IN: SPIE BiOS, 2016, San Francisco, California, United States. 2016-02-29.

Vítek, Libor; Gbelcová, Helena; Muchová, Lucie; Váňová, Kateřina; Zelenka, Jaroslav; Koníčková, Renata; Šuk, Jakub; Zadinova, Marie; Knejzlík, Zdeněk; Ahmad, Shakil; Fujisawa, Takeshi; Ahmed, Asif and Ruml, Tomáš (2014). Antiproliferative effects of carbon monoxide on pancreatic cancer. Digestive and liver disease, 46 (4), pp. 369-375.

Vítek, Libor; Gbelcová, Helena; Muchová, Lucie; Váňová, Kateřina; Zelenka, Jaroslav; Koníčková, Renata; Šuk, Jakub; Zadinova, Marie; Knejzlík, Zdeněk; Ahmad, Shakil; Fujisawa, Takeshi; Ahmed, Asif and Ruml, Tomáš (2014). Antiproliferative effects of carbon monoxide on pancreatic cancer. Digestive and Liver Disease, 46 (4), pp. 369-375.

Nayeri, Unzila A.; Buhimschi, Irina A.; Laky, Christine A.; Cross, Sarah N.; Duzyj, Christina M.; Ramma, Wenda; Sibai, Baha M.; Funai, Edmund F.; Ahmed, Asif and Buhimschi, Catalin S. (2014). Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia. Hypertension, Publis ,

Wegiel, Barbara; Gallo, David; Csizmadia, Eva; Harris, Clair; Belcher, John; Vercellotti, Gregory M.; Penacho, Nuno; Seth, Pankaj; Sukhatme, Vikas; Ahmed, Asif; Pandolfi, Pier Paolo; Helczynski, Leszek; Bjartell, Anders; Persson, Jenny Liao and Otterbein, Leo E. (2013). Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth. Cancer Research, 73 (23), pp. 7009-7021.

Wang, Keqing; Ahmad, Shakil; Cai, Meng; Rennie, Jillian; Fujisawa, Takeshi; Crispi, Fatima; Baily, James; Miller, Mark R.; Cudmore, Melissa; Hadoke, Patrick W.F.; Wang, Rui; Gratacós, Eduard; Buhimschi, Irina A.; Buhimschi, Catalin S. and Ahmed, Asif (2013). Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. Circulation, Early ,

Cudmore, Melissa J.; Hewett, Peter W.; Ahmad, Shakil; Wang, Ke-Qing; Cai, Meng; Al-Ani, Bahjat; Fujisawa, Takeshi; Ma, Bin; Sissaoui, Samir; Ramma, Wenda; Miller, Mark R.; Newby, David E.; Gu, Yuchun; Barleon, Bernhard; Weich, Herbert and Ahmed, Asif (2012). The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis. Nature Communications, 3 ,

Ramma, Wenda and Ahmed, Asif (2011). Is inflammation the cause of pre-eclampsia? Biochemical Society Transactions, 39 (6), pp. 1619-1627.

Ahmad, Shakil; Hewett, Peter W.; Al-Ani, Bahjat; Sissaoui, Samir; Fujisawa, Takeshi; Cudmore, Melissa J. and Ahmed, Asif (2011). Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis. Vascular Cell, 3 (1),

Cai, Jun; Wu, Lin; Qi, Xiaoping; Shaw, Lynn; Li Calzi, Sergio; Caballero, Sergio; Jiang, Wen G.; Vinores, Stanley A.; Antonetti, David; Ahmed, Asif; Grant, Maria B. and Boulton, Michael E. (2011). Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability. PLoS ONE, 6 (3),

Ahmed, Asif (2011). New insights into the etiology of preeclampsia:identification of key elusive factors for the vascular complications. Thrombosis Research, 127 (S3), S72-S75.

Ahmad, Shakil; Cudmore, Melissa J.; Wang, Keqing; Hewett, Peter W.; Potluri, Rahul; Fujisawa, Takeshi and Ahmed, Asif (2010). Angiopoietin-1 induces migration of monocytes in a tie-2 and integrin-independent manner. Hypertension, 56 (3), pp. 477-483.

Gould, Phillip S.; Gu, Mei; Liao, Jianqin; Ahmad, Shakil; Cudmore, Melissa J.; Ahmed, Asif and Vatish, Manu (2010). Upregulation of urotensin II receptor in preeclampsia causes in vitro placental release of soluble vascular endothelial growth factor receptor 1 in hypoxia. Hypertension, 56 (1), pp. 172-178.

Crispi, Fàtima; Bijnens, Bart; Figueras, Francesc; Bartrons, Joaquim; Eixarch, Elisenda; Le Noble, Ferdinand; Ahmed, Asif; le Noble, Ferdinand and Gratacós, Eduard (2010). Fetal growth restriction results in remodeled and less efficient hearts in children. Circulation, 121 (22), pp. 2427-2436.

Bergmann, Astrid; Ahmad, Shakil; Cudmore, Melissa J.; Gruber, Achim D.; Wittschen, Petra; Lindenmaier, Werner; Christofori, Gerhard; Gross, Volkmar; Ch. da Costa Gonzalves, Andrey; Gröne, Hermann-Josef; Ahmed, Asif and Weich, Herbert A. (2010). Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. Journal of Cellular and Molecular Medicine, 14 (6b), pp. 1857-1867.

Al-Ani, Bahjat; Hewett, Peter W.; Cudmore, Melissa J.; Fujisawa, Takeshi; Saifeddine, Mahmoud; Williams, Hannah; Ramma, Wenda; Sissaoui, Samir; Jayaraman, Padma-Sheela; Ohba, Motoi; Ahmad, Shakil; Hollenberg, Morley D. and Ahmed, Asif (2010). Activation of proteinase-activated receptor 2 stimulates soluble vascular endothelial growth factor receptor 1 release via epidermal growth factor receptor transactivation in endothelial cells. Hypertension, 55 (3), pp. 689-697.

Mee, Christopher J.; Farquhar, Michelle J.; Harris, Helen J.; Hu, Ke; Ramma, Wenda; Ahmed, Asif; Maurel, Patrick; Bicknell, Roy; Balfe, Peter and McKeating, Jane A. (2010). Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner. Gastroenterology, 138 (3), pp. 1134-1142.

Tintu, Andrei; Rouwet, Ellen; Verlohren, Stefan; Brinkmann, Joep; Ahmad, Shakil; Crispi, Fatima; van Bilsen, Marc; Carmeliet, Peter; Staff, Anne Cathrine; Tjwa, Marc; Cetin, Irene; Gratacos, Eduard; Hernandez-Andrade, Edgar; Hofstra, Leo; Jacobs, Michael; Lamers, Wouter H.; Morano, Ingo; Safak, Erdal; Ahmed, Asif and le Noble, Ferdinand (2009). Hypoxia induces dilated cardiomyopathy in the chick embryo:mechanism, intervention, and long-term consequences. PLoS ONE, 4 (4),

Crispi, Fàtima; Hernandez-Andrade, Edgar; Pelsers, Maurice M.A.L.; Plasencia, Walter; Benavides-Serralde, Jesus Andres; Eixarch, Elisenda; le Noble, Ferdinand; Ahmed, Asif; Glatz, Jan F.C.; Nicolaides, Kypros H. and Gratacos, Eduard (2008). Cardiac dysfunction and cell damage across clinical stages of severity in growth-restricted fetuses. American Journal of Obstetrics and Gynecology, 199 (3), 254.e1-254.e8.

Zhou, Cissy C.; Ahmad, Shakil; Mi, Tiejuan; Abbasi, Shahrzad; Xia, Lingwei; Day, Mary-Clare; Ramin, Susan M.; Ahmed, Asif; Kellems, Rodney E. and Xia, Yang (2008). Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling. Hypertension, 51 (4), pp. 1010-1019.

Roberts, Jonathan R.; Perkins, Gavin D.; Fujisawa, Takeshi; Pettigrew, Kerry A.; Gao, Fang; Ahmed, Asif and Thickett, David R. (2007). Vascular endothelial growth factor promotes physical wound repair and is anti-apoptotic in primary distal lung epithelial and A549 cells. Critical Care Medicine, 35 (9), pp. 2164-2170.

Zhou, Cissy Chenyi; Ahmad, Shakil; Mi, TieJuan; Xia, Lingwei; Abbasi, Shahrzad; Hewett, Peter W.; Sun, ChunXiao; Ahmed, Asif; Kellems, Rodney E. and Xia, Yang (2007). Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy. Circulation Research, 100 (1), pp. 88-95.

Al-Ani, Bahjat; Hewett, Peter W.; Ahmed, Suborna; Cudmore, Melissa; Fujisawa, Takeshi; Ahmad, Shakil and Ahmed, Asif (2006). The release of nitric oxide from S-nitrosothiols promotes angiogenesis. PLoS ONE, 1 (1),

Cudmore, Melissa; Ahmad, Shakil; Al-Ani, Bahjat; Hewett, Peter; Ahmed, Suborna and Ahmed, Asif (2006). VEGF-E activates endothelial nitric oxide synthase to induce angiogenesis via cGMP and PKG-independent pathways. Biochemical and Biophysical Research Communications, 345 (4), pp. 1275-1282.

Ahmad, Shakil and Ahmed, Asif (2005). Antiangiogenic effect of soluble vascular endothelial growth factor receptor-1 in placental angiogenesis. Endothelium, 12 (1-2), pp. 89-95.

Ramsden, James D.; Cocks, Helen C.; Shams, Munjiba; Nijjar, Sarbjit; Watkinson, John C.; Sheppard, Michael C.; Ahmed, Asif and Eggo, Margaret C. (2001). Tie-2 is expressed on thyroid follicular cells, is increased in goiter, and is regulated by thyrotropin through cyclic adenosine 3',5'-monophosphate. Journal of Clinical Endocrinology and Metabolism, 86 (6), pp. 2709-2716.

Ahmed, Asif; Rahman, Mahbubur; Zhang, Xian; Acevedo, Carmen H.; Nijjar, Sarbjit; Rushton, Ian; Bussolati, Benedetta and St. John, Justin (2000). Induction of placental heme oxygenase-1 is protective against TNFα-induced cytotoxicity and promotes vessel relaxation. Molecular Medicine, 6 (5), pp. 391-409.

Cai, Jun; Ahmad, Shakil; Jiang, Wen G.; Huang, Jianhua; Kontos, Christopher D.; Boulton, Mike and Ahmed, Asif Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells. Diabetes, 52 (12), pp. 2959-2568.

Ahmed, Asif; Fujisawa, Takeshi; Niu, Xi-Lin; Ahmad, Shakil; Al-Ani, Bahjat; Chudasama, Kunal; Abbas, Allyah; Potluri, Rahul; Bhandari, Vineet; Findley, Clarence M.; Lam, Gregory K.W.; Huang, Jianhua; Hewett, Peter W.; Cudmore, Melissa J. and Kontos, Christopher D. Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide. Circulation Research, 104 (12), pp. 1333-1336.

Bussolati, Benedetta; Ahmed, Asif; Pemberton, Helen; Landis, R. Clive; di Carlo, Francesco; Haskard, Dorian O. and Mason, Justin C. Bifunctional role for VEGF-induced heme oxygenase-1 in vivo:induction of angiogenesis and inhibition of leukocytic infiltration. Blood, 103 (3), pp. 761-766.

Ahmed, Asif Can hydrogen sulfide prevent preeclampsia and fetal growth restriction? Nitric Oxide, 31 (Suppl.), S17.

Ahmed, Asif and Cudmore, Melissa J. Can the biology of VEGF and haem oxygenases help solve pre-eclampsia? Biochemical Society Transactions, 37 (6), pp. 1237-1242.

Liang, Shenghui; Wang, Quanyi; Zhang, Weiwei; Zhang, Hailin; Tan, Shengjiang; Ahmed, Asif and Gu, Yuchun Carbon monoxide inhibits inward rectifier potassium channels in cardiomyocytes. Nature Communications, 5 ,

Campbell, Katherine; Buhimschi, Catalin; Ali, Unzila; Zhao, Guomao; Ahmed, Asif and Buhimschi, Irina Cervicovaginal vascular endothelial growth factor (VEGF) and risk of preterm birth (PTB). American Journal of Obstetrics and Gynecology, 204 (Suppl.), S200-S201.

Ahmad, Shakil; Hewett, Peter W.; Wang, Ping; Al-Ani, Bahjat; Cudmore, Melissa; Fujisawa, Takeshi; Haigh, Jody J.; le Noble, Ferdinand; Wang, Ling; Mukhopadhyay, Debabrata and Ahmed, Asif Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis. Circulation Research, 99 (7), pp. 715-722.

Hewett, Peter; Nijjar, Sarbjit; Shams, Munjiba; Morgan, Susan; Gupta, Janesh and Ahmed, Asif Down-regulation of angiopoietin-1 expression in menorrhagia. American Journal of Pathology, 160 (3), pp. 773-780.

Wang, Keqing; Ahmad, Shakil; Cai, Meng; Rennie, Jillian; Fujisawa, Takeshi; Crispi, Fatima; Baily, James; Miller, Mark R.; Cudmore, Melissa; Hadoke, Patrick W.F.; Wang, Rui; Gratacós, Eduard; Buhimschi, Irina A.; Buhimschi, Catalin S. and Ahmed, Asif Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. Circulation, 127 (25), pp. 2514-2522.

Ahmad, Shakil and Ahmed, Asif Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia. Circulation Research, 95 (9), pp. 884-891.

Dunk, Caroline and Ahmed, Asif Expression of VEGF-C and activation of its receptors VEGFR-2 and VEGFR-3 in trophoblast. Histology and Histopathology, 16 (2), pp. 359-375.

Krueger, Janna; Liu, Dong; Scholz, Katja; Zimmer, Anja; Shi, Yu; Klein, Christian; Siekmann, Arndt; Schulte-Merker, Stefan; Cudmore, Melissa; Ahmed, Asif and le Noble, Ferdinand Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo. Development, 138 (10), pp. 2111-2120.

Rosenberg, Victor A.; Buhimschi, Irina A.; Lockwood, Charles J.; Paidas, Michael J.; Dulay, Antonette T.; Ramma, Wenda; Abdel-Razeq, Sonya S.; Zhao, Guomao; Ahmad, Shakil; Ahmed, Asif and Buhimschi, Catalin S. Heparin elevates circulating soluble fms-like tyrosine kinase-1 immunoreactivity in pregnant women receiving anticoagulation therapy. Circulation, 124 (23), pp. 2543-2553.

Belgore, F.; Blann, Andrew; Neil, D.; Ahmed, Asif and Lip, Gregory Y.H. Localisation of members of the vascular endothelial growth factor (VEGF) family and their receptors in human atherosclerotic arteries. Journal of Clinical Pathology, 57 (3), pp. 266-272.

Cudmore, Melissa J.; Ahmad, Shakil; Sissaoui, Samir; Ramma, Wenda; Ma, Bin; Fujisawa, Takeshi; Al-Ani, Bahjat; Wang, Keqing; Cai, Meng; Crispi, Fatima; Hewett, Peter W.; Gratacós, Eduard; Egginton, Stuart and Ahmed, Asif Loss of Akt activity increases circulating soluble endoglin release in preeclampsia:identification of inter-dependency between Akt-1 and heme oxygenase-1. European Heart Journal, 33 (9), pp. 1150-1158.

Ahmed, Asif and Fujisawa, Takeshi Multiple roles of angiopoietins in atherogenesis. Current Opinion in Lipidology, 22 (5), pp. 380-385.

Cudmore, Melissa; Ahmad, Shakil; Al-Ani, Bahjat; Fujisawa, Takeshi; Coxall, Heather; Chudasama, Kunal; Devey, Luke R.; Wigmore, Stephen J.; Abbas, Allyah; Hewett, Peter W. and Ahmed, Asif Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1. Circulation, 115 (13), pp. 1789-1797.

Wegiel, Barbara; Gallo, David J.; Raman, Kathleen G.; Karlsson, Jenny M.; Ozanich, Brett; Chin, Beek Y.; Tzeng, Edith; Ahmad, Shakil; Ahmed, Asif; Baty, Catherine J. and Otterbein, Leo E. Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. Circulation, 121 (4), pp. 537-548.

Ahmed, Asif; Dunk, Caroline; Ahmad, Shakil and Khaliq, A. Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen - a review. Placenta, 21 (Supple), S16-S24.

Cudmore, Melissa J.; Ramma, Wenda; Cai, Meng; Fujisawa, Takeshi; Ahmad, Shakil; Al-Ani, Bahjat and Ahmed, Asif Resveratrol inhibits the release of soluble fms-like tyrosine kinase (sFlt-1) from human placenta. American Journal of Obstetrics and Gynecology, 206 (3), 253.e10–253.e15.

Hewett, Peter W.; Daft, Emma L.; Laughton, Charles A.; Ahmad, Shakil; Ahmed, Asif and Murray, J. Clifford Selective inhibition of the human tie-1 promoter with triplex-forming oligonucleotides targeted to ets binding sites. Molecular Medicine, 12 (1-3), pp. 8-16.

Findley, Clarence M.; Cudmore, Melissa J.; Ahmed, Asif and Kontos, Christopher D. VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling. Arteriosclerosis, Thrombosis, and Vascular biology, 27 (12), pp. 2619-2626.

Cai, Jun; Jiang, Wen G.; Ahmed, Asif and Boulton, Mike Vascular endothelial growth factor-induced endothelial cell proliferation is regulated by interaction between VEGFR-2, SH-PTP1 and eNOS. Microvascular Research, 71 (1), pp. 20-31.

Ramma, Wenda; Buhimschi, Irina A.; Zhao, Guomao; Dulay, Antonette T.; Nayeri, Unzila Ali; Buhimschi, Catalin S. and Ahmed, Asif The elevation in circulating anti-angiogenic factors is independent of markers of neutrophil activation in preeclampsia. Angiogenesis, 15 (3), pp. 333-340.