Browse by Aston Author

2023

Lisetto, Manuel, Fattorini, Mariagiulia, Lanza, Andrea, Gerdol, Marco, Griffin, Martin, Wang, Zhuo, Ferrara, Fortunato and Sblattero, Daniele (2023). Biochemical and Functional Characterization of the Three Zebrafish Transglutaminases 2. International Journal of Molecular Sciences, 24 (15),

2022

Pinton, Giulia, Wang, Zhuo, Balzano, Cecilia, Missaglia, Sara, Tavian, Daniela, Boldorini, Renzo, Fennell, Dean A., Griffin, Martin and Moro, Laura (2022). Corrigendum: CDKN2A determines mesothelioma cell fate to EZH2 inhibition. Frontiers in Oncology, 12 ,

Kurt-Celep, I, AN, Kilinc, Griffin, M and Telci, D (2022). Nitrosylation of Tissue Transglutaminase enhances fibroblast migration and regulates MMP activation. Matrix Biology, 105 ,

2021

Pinton, Giulia, Wang, Zhuo, Balzano, Cecilia, Missaglia, Sara, Tavian, Daniela, Boldorini, Renzo, Fennell, Dean A., Griffin, Martin and Moro, Laura (2021). CDKN2A Determines Mesothelioma Cell Fate to EZH2 Inhibition. Frontiers in Oncology, 11 ,

Fell, Shaun, Wang, Zhuo, Blanchard, Andy, Nanthakumar, Carmel and Griffin, Martin (2021). Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors. Amino Acids, 53 (2), pp. 205-217.

2020

Almami, Ibtesam S., Aldubayan, Maha A., Felemban, Shatha G., Alyamani, Najiah, Howden, Richard, Robinson, Alexander J., Pearson, Tom D.Z., Boocock, David, Algarni, Alanood S., Garner, A. Christopher, Griffin, Martin, Bonner, Philip L.R. and Hargreaves, Alan J. (2020). Neurite outgrowth inhibitory levels of organophosphates induce tissue transglutaminase activity in differentiating N2a cells:evidence for covalent adduct formation. Archives of Toxicology, 94 (11), pp. 3861-3875.

2019

Ayinde, Oluseyi, Wang, Zhuo, Pinton, Giulia, Moro, Laura and Griffin, Martin (2019). Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition. Oncotarget, 10 (44), pp. 4556-4569.

2018

Wang, Zhuo, Stuckey, Daniel J., Murdoch, Colin E., Camelliti, Patrizia, Lip, Gregory Y.H. and Griffin, Martin (2018). Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor. Cell Death and Disease, 9 ,

2017

Wang, Zhuo, Perez, Mileidys, Lee, Eun-Seo, Kojima, Soichi and Griffin, Martin (2017). The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial-mesenchymal transition. Cell Death and Disease, 8 (9),

Feriotto, G., Calza, R., Bergamini, C.M., Griffin, M., Wang, Z., Beninati, S., Ferretti, V., Marzola, E., Guerrini, R., Pagnoni, A., Cavazzini, A., Casciano, F. and Mischiati, C. (2017). Involvement of cell surface TG2 in the aggregation of K562 cells triggered by gluten. Amino Acids, 49 (3), 551–565.

Ayinde, Oluseyi, Wang, Zhuo and Griffin, Martin (2017). Tissue transglutaminase induces epithelial-mesenchymal-transition and the acquisition of stem cell like characteristics in colorectal cancer cells. Oncotarget, 8 (12), pp. 20025-20041.

Zonca, Sara, Pinton, Giulia, Wang, Zhuo, Soluri, Maria Felicia, Tavian, Daniela, Griffin, Martin, Sblattero, Daniele and Moro, Laura (2017). Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia. Cell Death and Disease, 8 (2),

2016

Nyabam, Samuel, Wang, Zhuo, Thibault, Thomas, Ayinde, Oluseyi, Basar, Rameeza, Marshall, Lindsay and Griffin, Martin (2016). A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis. BBA - Molecular Cell Research, 1863 (9), pp. 2234-2244.

Kiraly, Robert, Thangaraju,, Kiruphagaran, Nagy, Zsófia, Collighan, Russell, Nemes, Zoltán, Griffin, Martin and Fésüs, László (2016). Isopeptidase activity of human transglutaminase 2:disconnection from transamidation and characterization by kinetic parameters. Amino Acids, 48 (1), pp. 31-40.

2015

Badarau, Eduard, Wang, Zhuo, Rathbone, Dan L., Costanzi, Andrea, Thibault, Thomas, Murdoch, Colin E., El Alaoui, Said, Bartkeviciute, Milda and Griffin, Martin (2015). Development of potent and selective tissue transglutaminase inhibitors:their effect on TG2 function and application in pathological conditions. Chemistry and Biology, 22 (10), pp. 1347-1361.

Nadella, Vinod, Wang, Zhuo, Johnson, Timothy S., Griffin, Martin and Devitt, Andrew (2015). Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells. BBA - Molecular Cell Research, 1853 (1), pp. 201-212.

2013

Nadalutti, Cristina A., Korponay-Szabo, Ilma R., Kaukinen, Katri, Wang, Zhuo, Griffin, Martin, Mäki, Markku and Lindfors, Katri (2013). Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA. PLoS ONE, 8 (10),

Kalliokoski, Suvi, Sulic, Ana-Marija, Korponay-Szabó, Ilma R., Szondy, Zsuzsa, Frias, Rafael, Perez, Mileidys A., Martucciello, Stefania, Roivainen, Anne, Pelliniemi, Lauri J., Esposito, Carla, Griffin, Martin, Sblattero, Daniele, Mäki, Markku, Kaukinen, Katri, Lindfors, Katri and Caja, Sergio (2013). Celiac disease-specific TG2-targeted autoantibodies inhibit angiogenesis ex vivo and in vivo in mice by interfering with endothelial cell dynamics. PLoS ONE, 8 (6),

Wang, Zhuo and Griffin, Martin (2013). The role of TG2 in regulating S100A4-mediated mammary tumour cell migration. PLoS ONE, 8 (3),

Badarau, Eduard, Collighan, Russell J. and Griffin, Martin (2013). Recent advances in the development of tissue transglutaminase (TG2) inhibitors. Amino Acids, 44 (1), pp. 119-127.

Wang, Z., Perez, M., Caja, S., Melino, G., Johnson, T.S., Lindfors, K. and Griffin, M. (2013). A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis. Cell Death and Disease, 4 (9),

2012

Wang, Zhuo, Collighan, Russell, Pytel, Kamila, Rathbone, Dan L, Li, Xiaoling and Griffin, Martin (2012). Characterization of heparin-binding site of tissue transglutaminase:its importance in cell surface targeting, matrix deposition, and cell signaling. Journal of Biological Chemistry, 287 (16), pp. 13063-13083.

2011

Kotsakis, Panayiotis, Wang, Zhuo, Collighan, Russell John and Griffin, Martin (2011). The role of tissue transglutaminase (TG2) in regulating the tumour progression of the mouse colon carcinoma CT26. Amino Acids, 41 (4), pp. 909-921.

Sarang, Zsolt, Köröskényi, Krisztina, Pallai, Anna, Duró, Edina, Melino, Gerry, Griffin, Martin, Fésüs, László and Szondy, Zsuzsa (2011). Transglutaminase 2 null macrophages respond to lipopolysaccharide stimulation by elevated proinflammatory cytokine production due to an enhanced αvβ3 integrin-induced Src tyrosine kinase signaling. Immunology Letters, 138 (1), pp. 71-78.

2010

Wang, Zhuo, Collighan, Russell J, Gross, Stephane R, Danen, Erik H. J., Orend, Gertraud, Telci, Dilek and Griffin, Martin (2010). RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 and α5β1 integrin co-signaling. Journal of Biological Chemistry, 285 (51), pp. 40212-40129.

Mutch, N.J., Koikkalainen, J.S., Fraser, S.R., Duthie, K.M., Griffin, Martin, Mitchell, J., Watson, H.G. and Booth, N.A. (2010). Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis. Journal of Thrombosis and Haemostasis, 8 (9), pp. 2017-2024.

Chau, David Y.S., Tint, Naing L., Collighan, Russell J, Griffin, Martin, Dua, Harminder S., Shakesheff, Kevin M. and Rose, Felicity R.A.J. (2010). The visualisation of vitreous using surface modified poly(lactic-co-glycolic acid) microparticles. British Journal of Ophthalmology, 94 (5), pp. 648-653.

2009

Telci, Dilek, Collighan, Russell, Basaga, Huveyda and Griffin, Martin (2009). Increased TG2 expression can result in induction of transforming growth factor β1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide. Journal of Biological Chemistry, 284 (43), pp. 29547-29558.

Huang, Linghong, Haylor, John L., Hau, Zoe, Jones, Richard A., Vickers, Melissa E., Wagner, Bart, Griffin, Martin, Saint, Robert E., Coutts, Ian G.C., El Nahas, A. Meguid and Johnson, Timothy S. (2009). Transglutaminase inhibition ameliorates experimental diabetic nephropathy. Kidney international, 76 (4), pp. 383-394.

2008

Telci, Dilek, Wang, Zhuo, Li, Xiaoling, Verderio, Elisabetta A.M., Humphries, Martin J., Baccarini, Manuela, Basaga, Huveyda and Griffin, Martin (2008). Fibronectin-tissue transglutaminase matrix rescues RGD-impaired celladhesion through syndecan-4 and β integrin co-signaling. Journal of Biological Chemistry, 283 (30), pp. 20937-20947.

2006

Beck, Katy E., De Girolamo, Luigi A., Griffin, Martin and Billett, E. Ellen (2006). The role of tissue transglutaminase in 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells. Neuroscience Letters, 405 (1-2), pp. 46-51.

2004

Skill, Nicholas J., Johnson, Timothy S., Coutts, Ian G .C., Saint, Robert E., Fisher, Marie, Huang, Linghong, El Nahas, A. Meguid, Collighan, Russell and Griffin, Martin (2004). Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells. Journal of Biological Chemistry, 279 (46), pp. 47754-47762.

Trigwell, Susan M., Lynch, Paul T., Griffin, Martin, Hargreaves, Alan J. and Bonner, Philip L.R. (2004). An improved colorimetric assay for the measurement of transglutaminase (type II) ε-(γ-glutamyl) lysine cross-linking activity. Analytical Biochemistry, 330 (1), pp. 164-166.

2003

Verderio, Elisabetta A.M., Telci, Dilek, Okoye, Afam, Melino, Gerry and Griffin, Martin (2003). A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. Journal of Biological Chemistry, 278 (43), pp. 42604-42614.

2002

Balklava, Zita, Verderio, Elisabetta, Collighan, Russell, Gross, Stephane, Adams, Julian and Griffin, Martin (2002). Analysis of tissue transglutaminase function in the migration of Swiss 3T3 fibroblasts:the active-state conformation of the enzyme does not affect cell motility but is important for its secretion. Journal of Biological Chemistry, 277 (19), pp. 16567-16575.

1997

Johnson, Timothy S., Griffin, Martin, Thomas, Graham L., Skill, James, Cox, Anne, Bin Yang, Ben, Nicholas, B., Birckbichler, Paul J., Muchaneta-Kubara, Chiwoneso and El Nahas, A.Meguid (1997). The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis. Journal of Clinical Investigation, 99 (12), pp. 2950-2960.