What is radiomics?

Abstract

Radiomics is an emerging field that combines medical imaging techniques with data science to extract a vast array of quantitative features from images for clinical or research applications. These features, often imperceptible to the human eye, hold the potential to enhance healthcare and improve patient outcomes 1 through the identification of novel imaging markers that enable precise diagnosis, prognosis and treatment planning for a variety of childhood diseases. Integration of radiomics with other data types, such as genomics,2 offers opportunities for further multimodal insights, while longitudinal studies can establish radiomics’ role in monitoring disease progression or treatment response. Interpretability, accountability and reliability are essential within a healthcare setting. In contrast to ‘black-box’ artificial intelligence approaches, radiomics typically integrates interpretable algorithms, ensuring that predictions and insights can be understood, validated and trusted by clinicians, offering auditable workflows that are clear and reproducible. While traditional radiological reporting is invaluable, it may not fully exploit all the complex information embedded within modern imaging data. Radiomics can provide additional value to conventional radiological reporting, enhancing our ability to characterise pathology quantitatively and equipping clinicians with meaningful insights to reliably inform decision-making.

Publication DOI: https://doi.org/10.1136/archdischild-2024-328347
Divisions: College of Health & Life Sciences > School of Psychology
College of Health & Life Sciences
College of Health & Life Sciences > Aston Pharmacy School
Aston University (General)
Funding Information: TM is funded by the Help Harry Help Others Charity and Aston University for postgraduate research. DGK is funded by Aston University College of Health and Life Sciences via post-doctoral award. KC is funded by The Azaylia Foundation and Birmingham Childre
Additional Information: Copyright © Author(s) (or their employer(s)) 2025. This article has been accepted for publication in Archives of Disease in Childhood- Education and Practice, 2025 following peer review, and the Version of Record can be accessed online at: https://doi.org/10.1136/archdischild-2024-328347 . Reuse of this manuscript version (excluding any databases, tables, diagrams, photographs and other images or illustrative material included where a another copyright owner is identified) is permitted strictly pursuant to the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC-BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/.
Uncontrolled Keywords: Information Technology,Magnetic Resonance Imaging,Paediatrics,Statistics,Technology,Pediatrics, Perinatology, and Child Health
Last Modified: 30 Sep 2025 17:19
Date Deposited: 22 Sep 2025 13:18
Full Text Link:
Related URLs: https://ep.bmj. ... ild-2024-328347 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2025-09-09
Published Online Date: 2025-09-09
Accepted Date: 2025-08-25
Authors: Mulvany, Timothy (ORCID Profile 0009-0000-1699-4415)
Griffiths-King, Daniel (ORCID Profile 0000-0001-5797-9203)
Crombie, Katherine
Novak, Jan (ORCID Profile 0000-0001-5173-3608)
Apps, John R.

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