Close contact fluctuations:the seeding of signalling domains in the immunological synapse


We analyse the size and density of thermally induced regions of close contact in cell : cell contact interfaces within a harmonic potential approximation, estimating these regions to be below one-tenth of a micron across. Our calculations indicate that as the distance between the close contact threshold depth and the mean membrane-membrane separation increases, the density of close contact patches decreases exponentially while there is only a minimal variation in their mean size. The technique developed can be used to calculate the probability of first crossing in reflection symmetry violating systems. © Europhysics Letters Association.

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Divisions: College of Engineering & Physical Sciences > Systems analytics research institute (SARI)
Additional Information: © EPLA, 2007
Publication ISSN: 1286-4854
Last Modified: 22 Apr 2024 07:10
Date Deposited: 29 Apr 2014 14:05
Full Text Link: http://iopscien ... 075/77/4/48003/
http://www.scop ... 250312b52a7b4d6
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PURE Output Type: Article
Published Date: 2007-02-05
Authors: Chattopadhyay, Amit K. (ORCID Profile 0000-0001-5499-6008)
Burroughs, Nigel J.



Version: Accepted Version

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