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Article

Alyami, Hamad; Koner, Jasdip; Dahmash, Eman Z.; Bowen, James; Terry, David and Mohammed, Afzal R. (2016). Microparticle surface layering through dry coating:impact of moisture content and process parameters on the properties of orally disintegrating tablets. Journal of Pharmacy and Pharmacology, Early ,

Alyami, Hamad; Dahmash, Eman; Alyami, Fahad; Dahmash, Dania; Huynh, Chi; Terry, David and Mohammed, Afzal R. (2016). Dosage form preference consultation study in children and young adults:paving the way for patient-centred and patient-informed dosage form development. European Journal of Hospital Pharmacy, Online ,

Iyire, Affiong; Alayedi, Maryam and Mohammed, Afzal R. (2016). Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers. Scientific Reports, 6 ,

Dahmash, Eman Z. and Mohammed, Afzal R. (2016). Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug delivery. Drug Discovery Today, 21 (4), pp. 550-561.

Koner, Jasdip S.; Rajabi-Siahboomi, Ali; Bowen, James; Perrie, Yvonne; Kirby, Daniel and Mohammed, Afzal R. (2015). A holistic multi evidence approach to study the fragmentation behaviour of crystalline mannitol. Scientific Reports, 5 ,

ElShaer, Amr; Kaialy, Waseem; Akhtar, Noreen; Iyire, Affiong; Hussain, Tariq; Alany, Raid and Mohammed, Afzal R. (2015). A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets. European Journal of Pharmaceutics and Biopharmaceutics, 96 , 272–281.

Al-Khattawi, Ali; Koner, Jasdip; Rue, Peter; Kirby, Dan; Perrie, Yvonne; Rajabi-Siahboomi, Ali and Mohammed, Afzal R. (2015). A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance. European Journal of Pharmaceutics and Biopharmaceutics, 94 , pp. 1-10.

Dahmash, Eman Z. and Mohammed, Afzal R. (2015). Functionalised particles using dry powder coating in pharmaceutical drug delivery:promises and challenges. Expert Opinion on Drug Delivery, 12 (12), pp. 1867-1879.

Russell, Craig; Begum, Sumyra; Hussain, Yasar; Hussain, Majad; Huen, David; Rahman, Ayesha S; Perrie, Yvonne and Mohammed, Afzal R. (2015). Paediatric drug development of ramipril:reformulation, in vitro and in vivo evaluation. Journal of Drug Targeting, 23 (9), pp. 854-863.

ElShaer, Amr; Hanson, Peter and Mohammed, Afzal R. (2014). A novel concentration dependent amino acid ion pair strategy to mediate drug permeation using indomethacin as a model insoluble drug. European Journal of Pharmaceutical Sciences, 62 (1), pp. 124-131.

Al-Khattawi, Ali; Alyami, Hamad; Townsend, Bill; Ma, Xianghong and Mohammed, Afzal R. (2014). Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets. PLoS ONE, 9 (7),

Al-Khattawi, Ali; Iyire, Affiong; Dennison, Tom; Dahmash, Eman; Bailey, Clifford J; Smith, Julian; Rue, Peter and Mohammed, Afzal R. (2014). Systematic screening of compressed ODT excipients : cellulosic versus non-cellulosic. Current drug delivery, 11 , pp. 1-15.

Al-Khattawi, Ali; Iyire, Affiong; Dennison, Tom; Dahmash, Eman; Bailey, Clifford J.; Smith, Julian; Rue, Peter and Mohammed, Afzal R. (2014). Systematic screening of compressed ODT excipients:cellulosic versus non-cellulosic. Current Drug Delivery, 11 (4), pp. 486-500.

Al-Khattawi, Ali and Mohammed, Afzal R. (2014). Challenges and emerging solutions in the development of compressed orally disintegrating tablets. Expert Opinion on Drug Discovery, 9 (10), pp. 1109-1120.

Ali, M. Habib; Moghaddam, Behfar; Kirby, Daniel J.; Mohammed, Afzal R. and Perrie, Yvonne (2013). The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs. International Journal of Pharmaceutics, 453 (1), pp. 225-232.

Khan, Sheraz; Batchelor, Hannah; Hanson, Peter; Saleem, Imran Y.; Perrie, Yvonne and Mohammed, Afzal R. (2013). Dissolution rate enhancement, in vitro evaluation and investigation of drug release kinetics of chloramphenicol and sulphamethoxazole solid dispersions. Drug Development and Industrial Pharmacy, 39 (5), pp. 704-715.

Elshaer, Amr; Hanson, Peter and Mohammed, Afzal R (2013). A systematic and mechanistic evaluation of aspartic acid as filler for directly compressed tablets containing trimethoprim and trimethoprim aspartate. European Journal of Pharmaceutics and Biopharmaceutics, 84 (3), pp. 468-476.

Russell, Craig; Rahman, Ayesha and Mohammed, Afzal R. (2013). Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic delivery, 4 (3), pp. 395-413.

Tawfeek, Hesham M.; Evans, Andrew R.; Iftikhar, Abid; Mohammed, Afzal R.; Shabir, Anjumn; Somavarapu, Satyanarayana; Hutcheon, Gillian A. and Saleem, Imran Y. (2013). Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers. International Journal of Pharmaceutics, 441 (1-2), pp. 611-619.

Perrie, Yvonne; Singh Badhan, Raj; Kirby, Daniel J.; Lowry, Deborah; Mohammed, Afzal-Ur-Rahman and Ouyang, Defang (2012). The impact of ageing on the barriers to drug delivery. Journal of Controlled Release, 161 (2), pp. 389-398.

Bibi, Sagida; Lattmann, Eric; Mohammed, Afzal-Ur-Rahman and Perrie, Yvonne (2012). Trigger release liposome systems:local and remote controlled delivery? Journal of Microencapsulation, 29 (3), pp. 262-276.

Ali, M. Habib; Moghaddam, Behfar; Kirby, Daniel J.; Mohammed, Afzal R. and Perrie, Yvonne (2012). The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs. International journal of pharmaceutics, in pre ,

Moghaddam, Behfar; McNeil, Sarah E.; Zheng, Qinguo; Mohammed, Afzal R. and Perrie, Yvonne (2011). Exploring the correlation between lipid packaging in lipoplexes and their transfection efficacy. Pharmaceutics, 3 (4), pp. 848-864.

Al Husban, Farhan; Perrie, Yvonne and R. Mohammed, Afzal-Ur-Rahman (2011). Formulation of multiparticulate systems as lyophilised orally disintegrating tablets. European Journal of Pharmaceutics and Biopharmaceutics, 79 (3), pp. 627-634.

Khan, Sheraz; Batchelor, Hannah; Hanson, Peter; Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman (2011). Physicochemical characterisation, drug polymer dissolution and in vitro evaluation of phenacetin and phenylbutazone solid dispersions with polyethylene glycol 8000. Journal of Pharmaceutical Sciences, 100 (10), pp. 4281-4294.

Khan, Sheraz; Elshaer, Amr; Rahman, Ayesha S; Hanson, Peter; Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman (2011). Systems biology approach to study permeability of paracetamol and its solid dispersion. International Journal of Pharmaceutics, 417 (1-2), pp. 272-279.

Moghaddam, Behfar; Ali, Habib; Wilkhu, Jitinder; Kirby, Daniel J; Mohammed, Afzal-Ur-Rahman; Zheng, Qinguo and Perrie, Yvonne (2011). The application of monolayer studies in the understanding of liposomal formulations. International Journal of Pharmaceutics, 417 (1-2), pp. 235-244.

Tawfeek, Hesham; Khidr, Sayed; Samy, Eman; Ahmed, Sayed; Murphy, Mark; Mohammed, Afzaal; Shabir, Anjum; Hutcheon, Gillian and Saleem, Imran (2011). Poly(glycerol adipate-co-ω-pentadecalactone) spray-dried microparticles as sustained release carriers for pulmonary delivery. Pharmaceutical research, 28 (9), pp. 2086-2097.

Elshaer, Amr; Khan, Sheraz; Perumal, Dhaya; Hanson, Peter and Mohammed, Afzal-Ur-Rahman (2011). Use of amino acids as counterions improves the solubility of the BCS II model drug, indomethacin. Current Drug Delivery, 8 (4), pp. 363-372.

AlHusban, Farhan A; El-Shaer, Amr M; Jones, Rhys J and Mohammed, Afzal R (2010). Recent patents and trends in orally disintegrating tablets. Recent patents on drug delivery and formulation, 4 (3), pp. 178-197.

Ali, Habib; Kirby, Daniel J; Mohammed, Afzal-Ur-Rahman and Perrie, Yvonne (2010). Solubilisation of drugs within liposomal bilayers:alternatives to cholesterol as a membrane stabilising agent. Journal of Pharmacy and Pharmacology, 62 (11), pp. 1646-1655.

R Mohammed, Afzal-Ur-Rahman; Bramwell, Vincent W.; Kirby, Daniel J.; McNeil, Sarah E. and Perrie, Yvonne (2010). Increased potential of a cationic liposome-based delivery system:enhancing stability and sustained immunological activity in pre-clinical development. European Journal of Pharmaceutics and Biopharmaceutics, 76 (3), pp. 404-412.

AlHusban, Farhan; Elshaer, Amr M.; Kansara, Jiteen H.; Smith, Alan M.; Grover, Liam M.; Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman (2010). Investigation of formulation and process of lyophilised orally disintegrating tablet (ODT) using novel amino acid combination. Pharmaceutics, 2 (1), pp. 1-17.

AlHusban, Farhan; Perrie, Yvonne and Mohammed, Afzal R. (2010). Preparation, optimisation and characterisation of lyophilised rapid disintegrating tablets based on gelatin and saccharide. Current Drug Delivery, 7 (1), pp. 65-75.

Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman (2009). Pharmaceutics:a new open-access journal for all those interested in designing medicines. Pharmaceutics, 1 (1), pp. 1-2.

Chandrasekhar, Rahul; Hassan, Zahra; AlHusban, Farhan; Smith, Alan M. and Mohammed, Afzal R. (2009). The role of formulation excipients in the development of lyophilised fast-disintegrating tablets. European Journal of Pharmaceutics and Biopharmaceutics, 72 (1), pp. 119-129.

Mohammed, Afzal-Ur-Rahman; Coombes, Allan G.A. and Perrie, Yvonne (2007). Amino acids as cryoprotectants for liposomal delivery systems. European Journal of Pharmaceutical Sciences, 30 (5), pp. 406-413.

Perrie, Yvonne; Mohammed, Afzal U.R.; Vangala, Anil and McNeil, Sarah E. (2007). Environmental scanning electron microscopy offers real-time morphological analysis of liposomes and niosomes. Journal of Liposome Research, 17 (1), pp. 27-37.

Mohammed, Afzal-Ur-Rahman; Bramwell, Vincent W.; Coombes, Allan G.A. and Perrie, Yvonne (2006). Lyophilisation and sterilisation of liposomal vaccines to produce stable and sterile products. Methods, 40 (1), pp. 30-38.

Mohammed, Afzal-Ur-Rahman; Weston, N.; Coombes, A.G.A.; Fitzgerald, M. and Perrie, Yvonne (2004). Liposome formulation of poorly water soluble drugs:optimisation of drug loading and ESEM analysis of stability. International Journal of Pharmaceutics, 285 (1-2), pp. 23-34.

Al Husban, Farhan; Perrie, Yvonne and Mohammed, Afzal R Formulation and characterisation of lyophilised rapid disintegrating tablets using amino acids as matrix forming agents. European Journal of Pharmaceutics and Biopharmaceutics, 75 (2), pp. 254-262.

Al-Khattawi, Ali and Mohammed, Afzal R. Compressed orally disintegrating tablets:excipients evolution and formulation strategies. Expert Opinion on Drug Delivery, 10 (5), pp. 651-663.

Al-Khattawi, Ali and Mohammed, Afzal R. Excipients in medicines for children:scientific and regulatory paradigms. European Pharmaceutical Review, 19 (2), pp. 67-70.

Bibi, Sagida; Kaur, Randip; Henriksen-Lacey, Malou; McNeil, Sarah E; Wilkhu, Jitinder; Lattmann, Eric; Christensen, Dennis; Mohammed, Afzal-Ur-Rahman and Perrie, Yvonne Microscopy imaging of liposomes:from coverslips to environmental SEM. International Journal of Pharmaceutics, 417 (1-2), pp. 138-150.

Dennison, Thomas J.; Smith, Julian; Hofmann, Michael P.; Bland, Charlotte E.; Badhan, Raj K.; Al-Khattawi, Ali and Mohammed, Afzal R. Design of experiments to study the impact of process parameters on droplet size and development of non-invasive imaging techniques in tablet coating. PLoS ONE, 11 (8),

Dennison, Thomas J.; Smith, Julian C; Badhan, Raj K. and Mohammed, Afzal R. Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease:formulation, in vitro characterization and physiologically based pharmacokinetic modelling to assess bioavailability. Drug Design, Development and Therapy, 11 , pp. 811-826.

ElShaer, Amr; Hanson, Peter; Worthington, Tony; Lambert, Peter and Mohammed, Afzal R. Preparation and characterisation of amino acids based trimethoprim salts. Pharmaceutics, 4 (1), pp. 179-196.

Hofmann, M.P.; Mohammed, A.R.; Perrie, Y.; Gbureck, U. and Barralet, J.E. High-strength resorbable brushite bone cement with controlled drug-releasing capabilities. Acta Biomaterialia, 5 (1), pp. 43-49.

Jones, Rhys J.; Rajabi-Siahboomi, Ali; Levina, Marina; Perrie, Yvonne and Mohammed, Afzal R. The influence of formulation and manufacturing process parameters on the characteristics of lyophilized orally disintegrating tablets. Pharmaceutics, 3 (3), pp. 440-457.

Khan, Sheraz; Elshaer, Amr; Rahman, Ayesha S; Hanson, Peter; Perrie, Yvonne and Mohammed, Afzal-Ur-Rahman Genomic evaluation during permeability of indomethacin and its solid dispersion. Journal of Drug Targeting, 19 (8), pp. 615-623.

Perrie, Yvonne; Kirby, Daniel; Bramwell, Vincent W and Mohammed, Afzal R Recent developments in particulate-based vaccines. Recent patents on drug delivery and formulation, 1 (2), pp. 117-129.

Perrie, Yvonne; Mohammed, Afzal R.; Kirby, Daniel J.; McNeil, Sarah E. and Bramwell, Vincent W. Vaccine adjuvant systems: enhancing the efficacy of sub-unit protein antigens. International Journal of Pharmaceutics, 364 (2), pp. 272-280.

Russell, Craig; Rahman, Ayesha and Mohammed, Afzal R. Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic Delivery, 4 (3), pp. 395-413.

Shabir, Anjumn; Alhusban, Farhan; Perrie, Yvonne and Mohammed, Afzal R. Effects of ball-milling on PLGA polymer and its implication on lansoprazole-loaded nanoparticles. Journal of Basic and Clinical Pharmacy, 2 (2), pp. 71-82.

Book Section

Perrie, Yvonne; Ali, Habib; Kirby, Daniel J.; Mohammed, Afzal U.R.; McNeil, Sarah E. and Vangala, Anil (2017). Environmental scanning electron microscope imaging of vesicle systems. IN: Liposomes. d'Souza, Gerard G.M. (ed.) Methods in Molecular Biology . New York (US): Springer.

Mohammed, Afzal R.; ElShaer, Amr M.; Jones, Rhys J.; Khan, Sheraz and Russell, Craig A. (2014). Drug bioavailability and gene profiling:challenges and opportunities for pharmaceutics and personalized medicine. IN: Handbook of personalized medicine. Vizirianakis, Ioannis S. (ed.) Boca Raton, FL (US): CRC Press.

Perrie, Yvonne; Ali, Habib; Kirby, Daniel J.; Mohammed, Afzal U.R.; McNeil, Sarah E. and Vangala, Anil (2010). Environmental scanning electron microscope imaging of vesicle systems. IN: Liposomes. Weissig, Volkmar (ed.) Methods in molecular biology, 2 . UNSPECIFIED.

Christensen, Dennis; Korsholm, Karen; Wood, Grith Krøyer; Mohammed, Afzal; Bramwell, Vincent; Andersen, Peter; Agger, Else Marie and Perrie, Yvonne (2009). Liposomes in adjuvant systems for parenteral delivery of vaccines. IN: Delivery technologies for biopharmaceuticals: peptides, proteins, nucleic acids and vaccines. Jorgensen, Lene and Mørck Nielsen, Hanne (eds) Chirchester (UK): Wiley.

Thesis

Mohammed, Afzal U. R. (2005). Solubility enhancement of poorly water soluble drugs using liposome technology. PHD thesis, Aston University.