Browse by Aston Author

Heathman, Thomas R.j., Nienow, Alvin W., Rafiq, Qasim A., Coopman, Karen, Kara, Bo and Hewitt, Christopher J. (2018). Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development. Biochemical Engineering Journal, 136 , pp. 9-17.

Harrison, Richard P, Medcalf, Nicholas and Rafiq, Qasim A. (2018). Cell therapy-processing economics: small-scale microfactories as a stepping stone toward large-scale macrofactories. Regenerative medicine, 13 (2), pp. 159-173.

Nienow, A.W., Rafiq, Q.A., Heathman, T.R.J., Coopman, K. and Hewitt, C.J. (2016). Mixing theory for culture and harvest in bioreactors of human mesenchymal stem cells on microcarriers. Theoretical Foundations of Chemical Engineering, 50 (6), pp. 895-900.

Rafiq, Qasim A., Twomey, Karen, Kulik, Michael, Leschke, Christian, O'Dea, John, Callens, Sarah, Gentili, Chiara, Barry, Frank P. and Murphy, Mary (2016). Developing an automated robotic factory for novel stem cell therapy production. Regenerative medicine, 11 (4), pp. 351-354.

Rafiq, Qasim A. (2016). Toward a scalable and consistent manufacturing process for the production of human MSCs. Cell and Gene Therapy Insights, 2 (1), pp. 127-140.

Nienow, Alvin W., Hewitt, Christopher J., Heathman, Thomas R.J., Glyn, Veronica A.M., Fonte, Gonsalo N., Hanga, Mariana P., Coopman, Karen and Rafiq, Qasim A. (2016). Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms. Biochemical Engineering Journal, 108 , pp. 24-29.

Heathman, Thomas R.J., Rafiq, Qasim A., Chan, Alexander K.C., Coopman, Karen, Nienow, Alvin W., Kara, Bo and Hewitt, Christopher J. (2016). Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development. Biochemical Engineering Journal, 108 , pp. 14-23.

Heathman, Thomas R.J., Stolzing, Alexandra, Fabian, Claire, Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Kara, Bo and Hewitt, Christopher J. (2016). Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate. Cytotherapy, 18 (4), pp. 523-535.

Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W. and Hewitt, Christopher J. (2016). Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors. Biotechnology Journal, 11 (4), 473–486.

Heathman, Thomas R.J., Stolzing, Alexandra, Fabian, Claire, Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Kara, Bo and Hewitt, Christopher J. (2015). Serum-free process development:improving the yield and consistency of human mesenchymal stromal cell production. Cytotherapy, 17 (11), pp. 1524-1535.

Rafiq, Qasim A., Ortega, Ilida, Jenkins, Stuart I., Wilson, Samantha L., Patel, Asha K., Barnes, Amanda L., Adams, Christopher F., Delcassian, Derfogail and Smith, David (2015). The early career researcher's toolkit:translating tissue engineering, regenerative medicine and cell therapy products. Regenerative medicine, 10 (8), pp. 989-1003.

Rafiq, Qasim A. and Hewitt, Christopher J. (2015). Cell therapies:why scale matters. Pharmaceutical Bioprocessing, 3 (2), pp. 97-99.

Heathman, Thomas R.J., Glyn, Veronica A.M., Picken, Andrew, Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Kara, Bo and Hewitt, Christopher J. (2015). Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process. Biotechnology and Bioengineering, 112 (8), pp. 1696-1707.

Nienow, Alvin W., Rafiq, Qasim A., Coopman, Karen and Hewitt, Christopher J. (2014). A potentially scalable method for the harvesting of hMSCs from microcarriers. Biochemical Engineering Journal, 85 , pp. 79-88.