Peptide conjugate hydrogelators


Molecular gelators are currently receiving a great deal of attention. These are small molecules which, under the appropriate conditions, assemble in solution to, in the majority of cases, give long fibrillar structures which entangle to form a three-dimensional network. This immobilises the solvent, resulting in a gel. Such gelators have potential application in a number of important areas from drug delivery to tissue engineering. Recently, the use of peptide-conjugates has become prevalent with oligopeptides (from as short as two amino acids in length) conjugated to a polymer, alkyl chain or aromatic group such as naphthalene or fluorenylmethoxycarbonyl (Fmoc) being shown to be effective molecular gelators. The field of gelation is extremely large; here we focus our attention on the use of these peptide-conjugates as molecular hydrogelators.

Publication DOI:
Divisions: College of Engineering & Physical Sciences > School of Infrastructure and Sustainable Engineering > Chemical Engineering & Applied Chemistry
Additional Information: © The Royal Society of Chemistry 2010
Uncontrolled Keywords: molecular gelators,molecules,drug delivery,tissue engineering,peptide-conjugates,oligopeptides,Chemistry(all),Condensed Matter Physics
Publication ISSN: 1744-6848
Last Modified: 27 May 2024 07:09
Date Deposited: 16 Aug 2010 12:01
Full Text Link: http://pubs.rsc ... 813C/2010-04-16
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2010-04-16
Authors: Adams, Dave J.
Topham, Paul D. (ORCID Profile 0000-0003-4152-6976)


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