Can you tell your clunis from your cubitus? A benchmark for functional imaging


Advances in functional brain imaging have allowed the development of new investigative techniques with clinical application—ranging from presurgical mapping of eloquent cortex to identifying cortical regions involved in religious experiences. Similarly a variety of methods are available to referring physicians, ranging from metabolic measures such as functional magnetic resonance imaging and positron emission tomography to measurements based on electrical activity such as electroencephalography and magnetoencephalography. However, there are no universal benchmarks by which to judge between these methods. In this study we attempt to develop a standard for functional localisation, based on the known functional organisation of somatosensory cortex. Studies have shown spatially distinct sites of brain activity in response to stimulation of various body parts. Generally these studies have focused on areas with large cortical representations, such as the index finger and face. We tested the limits of magnetoencephalography source localisation by stimulation of body parts, namely the clunis and the cubitus, that map to proximal and relatively poorly represented regions of somatosensory cortex.

Publication DOI:
Divisions: College of Health & Life Sciences > School of Psychology
College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences > Clinical and Systems Neuroscience
College of Health & Life Sciences > Aston Institute of Health & Neurodevelopment (AIHN)
College of Health & Life Sciences
Additional Information: Copyright © 2004, BMJ Publishing Group Ltd.
Uncontrolled Keywords: functional brain imaging,presurgical mapping,eloquent cortex,religious experiences,metabolic measures,functional magnetic resonance imaging,positron emission tomography,electrical activity,electroencephalography,magnetoencephalography,standard,functional localisation,somatosensory cortex
Publication ISSN: 1756-1833
Last Modified: 22 May 2024 07:07
Date Deposited: 15 Nov 2010 14:33
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
http://www.bmj. ... 329/7480/1492.2 (Publisher URL)
PURE Output Type: Article
Published Date: 2004-12-18
Authors: Fisher, Alison E.
Barnes, Gareth R.
Hillebrand, Arjan
Burrow, Caroline
Furlong, Paul L. (ORCID Profile 0000-0002-9840-8586)
Holliday, Ian E.



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