Potapova, Elena V., Dremin, Viktor V., Shupletsov, Valery V., Kandurova, Ksenia Y. and Dunaev, Andrey V. (2025). Optical percutaneous needle biopsy in oncology. Light: Advanced Manufacturing, 6 (4),
Abstract
New technologies that combine standard procedures for tissue sample extraction and analysis with optical spectroscopy and imaging represent a new step in the development of tumour tissue diagnostics. Optical percutaneous needle biopsy is a promising method for increasing the diagnostic efficiency of the procedure by selecting the area for sample extraction and obtaining information about vascular changes and the metabolism of biological tissues at the needle tip. This study provides a comprehensive analysis of existing technical solutions to address various diagnostic tasks: studying the metabolic status of tissues for the adjustment of treatment protocols, differentiating healthy and tumour tissues for navigating puncture needles, and obtaining preliminary diagnoses of the nature of neoplasms. Technical systems for assessing the perfusion and metabolic characteristics of biological tissues using fine-needle probes have been described. Fine-needle probe designs for biopsies of various organs are also presented. The results of using optical percutaneous needle biopsy in liver and breast cancers are demonstrated.
| Publication DOI: | https://doi.org/10.37188/lam.2025.072 |
|---|---|
| Divisions: | College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT) |
| Additional Information: | © The Author(s) 2025. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article′s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article′s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Uncontrolled Keywords: | Diffuse reflectance spectroscopy,Fluorescence lifetime,Fluorescence spectroscopy,Optical biopsy,Percutaneous needle biopsy,Materials Science (miscellaneous),Instrumentation,Metals and Alloys,Industrial and Manufacturing Engineering |
| Publication ISSN: | 2831-4093 |
| Data Access Statement: | Data supporting the findings of this study are available from the corresponding author, V. V. D., upon request. upplementary information is available for this paper at https://doi.org/10.37188/lam.2025.072. |
| Last Modified: | 23 Mar 2026 08:17 |
| Date Deposited: | 17 Mar 2026 11:50 |
| Full Text Link: | |
| Related URLs: |
https://www.sco ... ns/105028904392
(Scopus URL) https://www.lig ... 88/lam.2025.072 (Publisher URL) |
PURE Output Type: | Article |
| Published Date: | 2025-10-31 |
| Accepted Date: | 2025-08-28 |
| Authors: |
Potapova, Elena V.
Dremin, Viktor V. ( 
0000-0001-6974-3505)
Shupletsov, Valery V. Kandurova, Ksenia Y. Dunaev, Andrey V. |
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