The use of the Baumber scoring system for metastatic disease of the vertebral column

Abstract

The prognostic assessment of metastatic spinal disease is predominantly tumour, rather than patient based. In 2021, Baumber et al. published a prognostic scoring system based on the patient as a whole rather than the tumour within the patient for metastatic disease of the appendicular skeleton. This paper assesses that prediction formula in those with metastatic disease of the spine. Survival was recorded for 65 individuals who underwent surgery for spinal metastatic disease. Using the same parameters and hazard ratio as Baumber, the projected survival was longer than actually occurred (over-prediction of 39% at 6 months and 54% at 12 months). The relative contributions of the individual parameters as part of the overall survival was different between the groups with a greater contribution seen if the individual had hyponatraemia, hypoalbuminaemia and low levels of creatinine. The reasons for the differences seen between the spinal and appendicular groups with regards to these parameters are not clear but may represent a poorer level of general health or the behaviour of different types and subtypes of malignancy. Further work is required to develop a specific tool for the calculation of prognosis in a metastatic spinal cohort using a general health perspective.

Publication DOI: https://doi.org/10.1186/s13104-025-07390-1
Divisions: College of Health & Life Sciences > Aston Medical School
College of Health & Life Sciences
Aston University (General)
Additional Information: Copyright © The Author(s) 2025. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
Uncontrolled Keywords: Aged,Male,Middle Aged,Prognosis,Tumour,Survival,Spinal Neoplasms - secondary - surgery - mortality - diagnosis,Metastasis,Spine,Female,Humans
Publication ISSN: 1756-0500
Last Modified: 06 Aug 2025 07:40
Date Deposited: 05 Aug 2025 09:04
Full Text Link:
Related URLs: https://bmcresn ... 104-025-07390-1 (Publisher URL)
PURE Output Type: Article
Published Date: 2025-07-22
Published Online Date: 2025-07-22
Accepted Date: 2025-07-14
Authors: Hodgson, Sam
Pynsent, Paul
Hughes, Simon
Rehousek, Petr
Gardner, Adrian (ORCID Profile 0000-0001-6532-7950)

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