Technical recommendations for analyzing oxylipins by liquid chromatography–mass spectrometry

Abstract

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography–mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.

Publication DOI: https://doi.org/10.1126/scisignal.adw1245
Divisions: College of Health & Life Sciences > School of Biosciences
College of Health & Life Sciences > Aston Medical School
Aston University (General)
Additional Information: This is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science Signaling, Volume 18 (2025). DOI: https://doi.org/10.1126/scisignal.adw1245
Publication ISSN: 1937-9145
Last Modified: 30 May 2025 16:17
Date Deposited: 27 May 2025 14:57
Full Text Link:
Related URLs: https://www.sci ... isignal.adw1245 (Publisher URL)
PURE Output Type: Article
Published Date: 2025-05-20
Authors: Schebb, Nils Helge
Kampschulte, Nadja
Hagn, Gerhard
Plitzko, Kathrin
authors inc., + 90
Spickett, Corinne (ORCID Profile 0000-0003-4054-9279)
Dias, Irundika (ORCID Profile 0000-0002-6620-8221)
Milic, Ivana (ORCID Profile 0000-0001-7531-7561)

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