Determinants of Maternal and Infant Omega-3 Status at 3 Months Postpartum: Findings from the APrON Longitudinal Cohort Study

Abstract

Omega-3 long chain polyunsaturated fatty acids (LCPUFAs) are important dietary components for maternal and infant health during pregnancy and lactation. This study investigated determinants of maternal and infant LCPUFAs status at three months postpartum and the relationship between maternal serum, mother's milk, and infant LCPUFAs. This cross-sectional study included mothers (n=1481) and their offspring (n=526) at three months postpartum from the APrON cohort. Maternal dietary intake (24-hour recall), blood samples from mothers and infants, and maternal milk were collected. Fatty acid composition (relative % of total fatty acids) was determined by gas-liquid chromatography. Linear regression analyses explored associations between diet, sociodemographic factors, and fatty acid status. In a multivariable-adjusted analysis, maternal total dietary intake (supplement + food) was positively associated with the percentage of docosahexaenoic acid (DHA, standardized(S) ß=0.394; ß=0.394; 95% CI: 0.192, 0.558; P

Publication DOI: https://doi.org/10.1016/j.ajcnut.2025.01.002
Divisions: College of Health & Life Sciences > School of Psychology
Funding Information: The APrON cohort was funded by a grant from Alberta Innovates-Health Solutions (grant/award number N/A), The Dairy Farmers of Canada (RES0047122) and Alberta Canola Producers (ACPC 202FO16). CJF holds a Canadian Research Chair Tier 1 in Human Nutrition an
Additional Information: Crown Copyright © 2025 Published by Elsevier Inc. on behalf of American Society for Nutrition. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Uncontrolled Keywords: fatty acids,dietary intake,human milk,lactation,docosahexaenoic acid
Publication ISSN: 1938-3207
Data Access Statement: The data underlying in this article are available upon request to APrON Project Director (E-mail: apron@ucalgary.ca) or visit https://apronstudy.ca/contact-us/
Last Modified: 02 Apr 2025 07:26
Date Deposited: 27 Jan 2025 14:50
Full Text Link:
Related URLs: https://www.sci ... 002916525000024 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2025-03
Published Online Date: 2025-01-07
Accepted Date: 2025-01-02
Submitted Date: 2024-10-07
Authors: Munhoz, Jaqueline
Wattar, Nour
Goruk, Susan
Pakseresht, Mohammadreza
Jarman, Megan (ORCID Profile 0000-0002-4477-9314)
Forbes, Laura
Bell, Rhonda C
Subhan, Fatheema B
Field, Catherine J

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