Casey, Ruth T., Hendriks, Emile, Deal, Cheri, Waguespack, Steven G., Wiegering, Verena, Redlich, Antje, Akker, Scott, Prasad, Rathi, Fassnacht, Martin, Clifton-Bligh, Roderick, Amar, Laurence, Bornstein, Stefan, Canu, Letizia, Charmandari, Evangelia, Chrisoulidou, Alexandra, Freixes, Maria Currás, de Krijger, Ronald, de Sanctis, Luisa, Fojo, Antonio, Ghia, Amol J., Huebner, Angela, Kosmoliaptsis, Vasilis, Kuehlen, Michaela, Raffaelli, Marco, Lussey-Lepoutre, Charlotte, Marks, Stephen D., Nilubol, Naris, Parasiliti-Caprino, Mirko, Timmers, Henri H.J.L.M., Zietlow, Anna Lena, Robledo, Mercedes, Gimenez-Roqueplo, Anne Paule, Grossman, Ashley B., Taïeb, David, Maher, Eamonn R., Lenders, Jacques W.M., Eisenhofer, Graeme, Jimenez, Camilo, Pacak, Karel and Pamporaki, Christina (2024). International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents. Nature Reviews Endocrinology, 20 (12), pp. 729-748.
Abstract
Phaeochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumours that arise not only in adulthood but also in childhood and adolescence. Up to 70–80% of childhood PPGL are hereditary, accounting for a higher incidence of metastatic and/or multifocal PPGL in paediatric patients than in adult patients. Key differences in the tumour biology and management, together with rare disease incidence and therapeutic challenges in paediatric compared with adult patients, mandate close expert cross-disciplinary teamwork. Teams should ideally include adult and paediatric endocrinologists, oncologists, cardiologists, surgeons, geneticists, pathologists, radiologists, clinical psychologists and nuclear medicine physicians. Provision of an international Consensus Statement should improve care and outcomes for children and adolescents with these tumours.
Publication DOI: | https://doi.org/10.1038/s41574-024-01024-5 |
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Divisions: | College of Health & Life Sciences > Aston Medical School |
Additional Information: | Copyright © Crown 2024, corrected publication 2024. This is an accepted manuscript of an article published in Nature Reviews Endocrinology. The published version is available at: https://doi.org/10.1038/s41574-024-01024-5 |
Uncontrolled Keywords: | Endocrinology, Diabetes and Metabolism,Endocrinology |
Publication ISSN: | 1759-5037 |
Last Modified: | 24 Dec 2024 08:22 |
Date Deposited: | 15 Oct 2024 12:13 |
Full Text Link: |
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Related URLs: |
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(Scopus URL) https://www.nat ... 574-024-01024-5 (Publisher URL) |
PURE Output Type: | Article |
Published Date: | 2024-12 |
Published Online Date: | 2024-08-15 |
Accepted Date: | 2024-07-17 |
Authors: |
Casey, Ruth T.
Hendriks, Emile Deal, Cheri Waguespack, Steven G. Wiegering, Verena Redlich, Antje Akker, Scott Prasad, Rathi Fassnacht, Martin Clifton-Bligh, Roderick Amar, Laurence Bornstein, Stefan Canu, Letizia Charmandari, Evangelia Chrisoulidou, Alexandra Freixes, Maria Currás de Krijger, Ronald de Sanctis, Luisa Fojo, Antonio Ghia, Amol J. Huebner, Angela Kosmoliaptsis, Vasilis Kuehlen, Michaela Raffaelli, Marco Lussey-Lepoutre, Charlotte Marks, Stephen D. Nilubol, Naris Parasiliti-Caprino, Mirko Timmers, Henri H.J.L.M. Zietlow, Anna Lena Robledo, Mercedes Gimenez-Roqueplo, Anne Paule Grossman, Ashley B. Taïeb, David Maher, Eamonn R. Lenders, Jacques W.M. Eisenhofer, Graeme Jimenez, Camilo Pacak, Karel Pamporaki, Christina |