Glycaemic outcomes in people living with diabetes under 65 and over 65 years old using an intermittently scanned continuous glucose monitoring system

Abstract

OBJECTIVE: Intermittently scanned continuous glucose monitoring (isCGM) has revolutionised the care of people with diabetes but its uptake and benefits in older adults are not well known. We examined the impact of isCGM (Freestyle Libre, FSL) on glycaemic outcomes in younger (⩽65 years) and older adults (>65 years) with diabetes. DESIGN AND METHODS: In total, 2260 adult patients registered on the Libreview account at University Hospitals Birmingham NHS Foundation Trust, UK, were included. Inclusion criteria: all patients with type 1 and type 2 diabetes aged >18 years, use of isCGM >6 months, scanning at least 6 times/day. Demographics, diabetes history and glycaemic outcomes (time in range (TIR), time above range and time below range (TBR), estimated HbA1c, HbA1c at start and at end of study) were collected by accessing electronic patient records and Libreview. Outcomes were compared between age groups ⩽65 or >65 years old. RESULTS: Most patients were of Caucasian ethnicity (⩽65 years 68%, >65 years 73%) and had type 1 diabetes. Mean duration of diabetes was 19.5 years (range 0-65 years) and 34.5 years (range 0-79 years) for ⩽65 and >65 years, respectively. Only a quarter of those ⩽65 years achieved (219/943; 23.2%) their age specific TIR target compared to 69% (78/113) of those >65 years cohort, while 70.1% (663/946) of ⩽65 years and 40.7% (46/113) of >65 years achieved their age-specific TBR target. When the less strict ⩽65 years TBR target was applied, 75% (85/113) of >65 years cohort achieved this. CONCLUSION: FSL use was associated with improved glycaemic outcomes across all age groups. Individualised targets may be needed to improve TBR in those aged >65 years.

Publication DOI: https://doi.org/10.1177/20420188241269133
Divisions: College of Health & Life Sciences > School of Biosciences
College of Health & Life Sciences
Aston University (General)
Additional Information: Copyright © The Author(s), 2024. This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the Sage and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Uncontrolled Keywords: continuous glucose monitoring,older adults,type 1 diabetes mellitus
Publication ISSN: 2042-0188
Last Modified: 03 Dec 2024 08:23
Date Deposited: 23 Aug 2024 11:36
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Related URLs: https://journal ... 420188241269133 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2024-08-20
Published Online Date: 2024-08-20
Accepted Date: 2024-06-23
Authors: Wong, Carol
De Bray, Anne
Ul Hassan, Naeem
Almohandes, Ahmed
Thant, Kyi Zin
Gill, Sofia
Gill, Dayna
Forsdick, Hayley
Sinclair, Alan J.
Karamat, Muhammad Ali
Bellary, Srikanth (ORCID Profile 0000-0002-5924-5278)

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