Association between gait speed deterioration and EEG abnormalities

Abstract

Physical and cognitive decline at an older age is preceded by changes that accumulate over time until they become clinically evident difficulties. These changes, frequently overlooked by patients and health professionals, may respond better than fully established conditions to strategies designed to prevent disabilities and dependence in later life. The objective of this study was twofold; to provide further support for the need to screen for early functional changes in older adults and to look for an early association between decline in mobility and cognition. A cross-sectional cohort study was conducted on 95 active functionally independent community-dwelling older adults in Havana, Cuba. We measured their gait speed at the usual pace and the cognitive status using the MMSE. A value of 0.8 m/s was used as the cut-off point to decide whether they presented a decline in gait speed. A quantitative analysis of their EEG at rest was also performed to look for an associated subclinical decline in brain function. Results show that 70% of the sample had a gait speed deterioration (i.e., lower than 0.8 m/s), of which 80% also had an abnormal EEG frequency composition for their age. While there was no statistically significant difference in the MMSE score between participants with a gait speed above and below the selected cut-off, individuals with MMSE scores below 25 also had a gait speed

Publication DOI: https://doi.org/10.1371/journal.pone.0305074
Divisions: College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Audiology
Aston University (General)
Funding Information: VRR (the corresponding author) received funds from the Global Challenge Research Fund - Aston University internal call (ID-28014), but the funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscr
Additional Information: Copyright © 2024 García-Agustin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Uncontrolled Keywords: Aged,Aged, 80 and over,Cognitive Dysfunction/physiopathology,Cohort Studies,Cross-Sectional Studies,Electroencephalography,Female,Gait/physiology,Humans,Male,Middle Aged,Walking Speed
Publication ISSN: 1932-6203
Data Access Statement: Data is available from the Aston Data Explorer database (accession number: https://doi.org/10.1706/researchdata.aston.ac.uk.00000557)
Last Modified: 02 Dec 2024 09:06
Date Deposited: 06 Jun 2024 13:04
Full Text Link:
Related URLs: https://journal ... al.pone.0305074 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2024-06-04
Published Online Date: 2024-06-04
Accepted Date: 2024-04-12
Submitted Date: 2022-06-25
Authors: García-Agustin, Daysi
Rodríguez-Rodríguez, Valia (ORCID Profile 0000-0002-6085-285X)
Morgade-Fonte, Rosa Ma
Bobes, María A.
Galán-García, Lídice

Download

[img]

Version: Published Version

License: Creative Commons Attribution

| Preview

Export / Share Citation


Statistics

Additional statistics for this record