Alexander, Stephen P H, Mathie, Alistair A, Peters, John A, Veale, Emma L, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Davies, Jamie A, Aldrich, Richard W, Attali, Bernard, Baggetta, Austin M, Becirovic, Elvir, Biel, Martin, Bill, Roslyn M, Caceres, Ana I, Catterall, William A, Conner, Alex C, Davies, Paul, De Clerq, Katrien, Delling, Markus, Di Virgilio, Francesco, Falzoni, Simonetta, Fenske, Stefanie, Fortuny-Gomez, Anna, Fountain, Samuel, George, Chandy, Goldstein, Steve A N, Grimm, Christian, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Hu, Meiqin, Ijzerman, Ad P, Jabba, Sairam V, Jarvis, Mike, Jensen, Anders A, Jordt, Sven E, Kaczmarek, Leonard K, Kellenberger, Stephan, Kennedy, Charles, King, Brian, Kitchen, Philip, Liu, Qiang, Lynch, Joseph W, Meades, Jessica, Mehlfeld, Verena, Nicke, Annette, Offermanns, Stefan, Perez-Reyes, Edward, Plant, Leigh D, Rash, Lachlan, Ren, Dejian, Salman, Mootaz M, Sieghart, Werner, Sivilotti, Lucia G, Smart, Trevor G, Snutch, Terrance P, Tian, Jinbin, Trimmer, James S, Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan D, Winn, Brenda T, Wulff, Heike, Xu, Haoxing, Yang, Fan, Fang, Wei, Yue, Lixia, Zhang, Xiaoli and Zhu, Michael (2023). The Concise Guide to PHARMACOLOGY 2023/24: Ion channels. British Journal of Pharmacology, 180 (Suppl.), S145-S222.
Abstract
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16178. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
Publication DOI: | https://doi.org/10.1111/bph.16178 |
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Divisions: | College of Health & Life Sciences > School of Biosciences |
Additional Information: | Copyright © 2023 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society. This is an open access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
Uncontrolled Keywords: | Humans,Databases, Pharmaceutical,Ion Channels/chemistry,Ligands,Receptors, G-Protein-Coupled,Databases, Factual,Pharmacology |
Publication ISSN: | 1476-5381 |
Last Modified: | 06 Aug 2024 09:58 |
Date Deposited: | 21 Dec 2023 15:10 |
Full Text Link: | |
Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) https://bpspubs ... .1111/bph.16178 (Publisher URL) |
PURE Output Type: | Article |
Published Date: | 2023-12-20 |
Accepted Date: | 2023-12-01 |
Authors: |
Alexander, Stephen P H
Mathie, Alistair A Peters, John A Veale, Emma L Striessnig, Jörg Kelly, Eamonn Armstrong, Jane F Faccenda, Elena Harding, Simon D Davies, Jamie A Aldrich, Richard W Attali, Bernard Baggetta, Austin M Becirovic, Elvir Biel, Martin Bill, Roslyn M ( ![]() Caceres, Ana I Catterall, William A Conner, Alex C Davies, Paul De Clerq, Katrien Delling, Markus Di Virgilio, Francesco Falzoni, Simonetta Fenske, Stefanie Fortuny-Gomez, Anna Fountain, Samuel George, Chandy Goldstein, Steve A N Grimm, Christian Grissmer, Stephan Ha, Kotdaji Hammelmann, Verena Hanukoglu, Israel Hu, Meiqin Ijzerman, Ad P Jabba, Sairam V Jarvis, Mike Jensen, Anders A Jordt, Sven E Kaczmarek, Leonard K Kellenberger, Stephan Kennedy, Charles King, Brian Kitchen, Philip ( ![]() Liu, Qiang Lynch, Joseph W Meades, Jessica Mehlfeld, Verena Nicke, Annette Offermanns, Stefan Perez-Reyes, Edward Plant, Leigh D Rash, Lachlan Ren, Dejian Salman, Mootaz M Sieghart, Werner Sivilotti, Lucia G Smart, Trevor G Snutch, Terrance P Tian, Jinbin Trimmer, James S Van den Eynde, Charlotte Vriens, Joris Wei, Aguan D Winn, Brenda T Wulff, Heike Xu, Haoxing Yang, Fan Fang, Wei Yue, Lixia Zhang, Xiaoli Zhu, Michael |