In-vivo corneal confocal microscopy::Imaging analysis, biological insights and future directions

Abstract

In-vivo corneal confocal microscopy is a powerful imaging technique which provides clinicians and researcher with the capabilities to observe microstructures at the ocular surfaces in significant detail. In this Mini Review, the optics and image analysis methods with the use of corneal confocal microscopy are discussed. While novel insights of neuroanatomy and biology of the eyes, particularly the ocular surface, have been provided by corneal confocal microscopy, some debatable elements observed using this technique remain and these are explored in this Mini Review. Potential improvements in imaging methodology and instrumentation are also suggested.

Publication DOI: https://doi.org/10.1038/s42003-023-05005-8
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences > School of Optometry
Additional Information: Copyright © The Author(s) 2023. This article is licensed under a Creative Commons Attribution 4.0 International License.
Publication ISSN: 2399-3642
Last Modified: 07 Oct 2024 07:48
Date Deposited: 21 Jun 2023 07:16
Full Text Link:
Related URLs: https://www.nat ... 003-023-05005-8 (Publisher URL)
PURE Output Type: Review article
Published Date: 2023-06-19
Published Online Date: 2023-06-19
Accepted Date: 2023-05-31
Submitted Date: 2023-03-14
Authors: Chiang, Jeremy Chung Bo (ORCID Profile 0000-0002-6133-7411)
Roy, Maitreyee
Kim, Juno
Markoulli, Maria
Krishnan, Arun V.

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