Possible contraindications and adverse reactions associated with the use of ocular nutritional supplements


The role of oxidation in the development of age-related eye disease has prompted interest in the use of nutritional supplementation for prevention of onset and progression. Our aim is to highlight possible contraindications and adverse reactions of isolated or high dose ocular nutritional supplements. Web of Science and PubMed database searches were carried out, followed by a manual search of the bibliographies of retrieved articles. Vitamin A should be avoided in women who may become pregnant, in those with liver disease, and in people who drink heavily. Relationships have been found between vitamin A and reduced bone mineral density, and beta-carotene and increased risk of lung cancer in smoking males. Vitamin E and Ginkgo biloba have anticoagulant and anti-platelet effects respectively, and high doses are contraindicated in those being treated for vascular disorders. Those patients with contraindications or who are considered at risk of adverse reactions should be advised to seek specialist dietary advice via their medical practitioner. © 2005 The College of Optometrists.

Publication DOI: https://doi.org/10.1111/j.1475-1313.2005.00294.x
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG)
College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Vision, Hearing and Language
Additional Information: © 2005 The College of Optometrists. Published by Wiley-Blackwell.
Uncontrolled Keywords: adverse reactions,contraindications,ginkgo biloba,nutritional supplementation,vitamin A,vitamin E,zZinc,Ophthalmology,Sensory Systems,Health Professions(all)
Publication ISSN: 1475-1313
Last Modified: 31 May 2024 07:07
Date Deposited: 08 Apr 2010 11:49
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
http://onlineli ... 0294.x/abstract (Publisher URL)
PURE Output Type: Article
Published Date: 2005-05
Authors: Bartlett, Hannah E. (ORCID Profile 0000-0002-7531-6902)
Eperjesi, Frank (ORCID Profile 0000-0003-4358-0095)



Version: Accepted Version

| Preview

Export / Share Citation


Additional statistics for this record