Cognitive training and remediation interventions for substance use disorders: A Delphi consensus study


Aims: Substance use disorders (SUD) are associated with cognitive deficits that are not always addressed in current treatments, and this hampers recovery. Cognitive training and remediation interventions are well suited to fill the gap for managing cognitive deficits in SUD. We aimed to reach consensus on recommendations for developing and applying these interventions. Design, Setting and Participants: We used a Delphi approach with two sequential phases: survey development and iterative surveying of experts. This was an on-line study. During survey development, we engaged a group of 15 experts from a working group of the International Society of Addiction Medicine (Steering Committee). During the surveying process, we engaged a larger pool of experts (n = 54) identified via recommendations from the Steering Committee and a systematic review. Measurements: Survey with 67 items covering four key areas of intervention development: targets, intervention approaches, active ingredients and modes of delivery. Findings: Across two iterative rounds (98% retention rate), the experts reached a consensus on 50 items including: (i) implicit biases, positive affect, arousal, executive functions and social processing as key targets of interventions; (ii) cognitive bias modification, contingency management, emotion regulation training and cognitive remediation as preferred approaches; (iii) practice, feedback, difficulty-titration, bias modification, goal-setting, strategy learning and meta-awareness as active ingredients; and (iv) both addiction treatment work-force and specialized neuropsychologists facilitating delivery, together with novel digital-based delivery modalities. Conclusions: Expert recommendations on cognitive training and remediation for substance use disorders highlight the relevance of targeting implicit biases, reward, emotion regulation and higher-order cognitive skills via well-validated intervention approaches qualified with mechanistic techniques and flexible delivery options.

Publication DOI:
Divisions: College of Health & Life Sciences > Aston Institute of Health & Neurodevelopment (AIHN)
College of Health & Life Sciences
College of Health & Life Sciences > School of Psychology
Additional Information: Copyright © 2022, The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. Funding Information: This study was funded by grants MRF1141214 from the Australian Medical Research Future Fund and GNT2009464 from the National Health and Medical Research Council to Antonio Verdejo‐Garcia. Open access publishing facilitated by Monash University, as part of the Wiley ‐ Monash University agreement via the Council of Australian University Librarians.
Uncontrolled Keywords: Cognitive remediation,Delphi method,cognitive training,interventions,neuroscience,treatment,Medicine (miscellaneous),Psychiatry and Mental health
Publication ISSN: 1360-0443
Last Modified: 22 May 2024 17:50
Date Deposited: 16 Dec 2022 17:14
Full Text Link:
Related URLs: https://onlinel ... .1111/add.16109 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2022-12-12
Published Online Date: 2022-12-12
Accepted Date: 2022-11-23
Authors: Verdejo‐Garcia, Antonio
Rezapour, Tara
Giddens, Emily
Zonoozi, Arash Khojasteh
Rafei, Parnian
Berry, Jamie
Caracuel, Alfonso
Copersino, Marc L.
Field, Matt
Garland, Eric L.
Lorenzetti, Valentina
Malloy‐Diniz, Leandro
Manning, Victoria
Marceau, Ely M.
Pennington, David L.
Strickland, Justin C.
Wiers, Reinout
Fairhead, Rahia
Anderson, Alexandra
Bell, Morris
Boendermaker, Wouter J.
Brooks, Samantha
Bruno, Raimondo
Campanella, Salvatore
Cousijn, Janna
Cox, Miles
Dean, Andrew C.
Ersche, Karen D.
Franken, Ingmar
Froeliger, Brett
Gamito, Pedro
Gladwin, Thomas E.
Goncalves, Priscila D.
Houben, Katrijn
Jacobus, Joanna
Jones, Andrew
Kaag, Anne M.
Lindenmeyer, Johannes
McGrath, Elly
Nardo, Talia
Oliveira, Jorge
Pennington, Charlotte R. (ORCID Profile 0000-0002-5259-642X)
Perrykkad, Kelsey
Piercy, Hugh
Rupp, Claudia I.
Schulte, Mieke H. J.
Squeglia, Lindsay M.
Staiger, Petra
Stein, Dan J.
Stein, Jeff
Stein, Maria
Stoops, William W.
Sweeney, Mary
Witkiewitz, Katie
Woods, Steven P.
Yi, Richard
Zhao, Min
Ekhtiari, Hamed



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