Macro- and Microvascular Function in Middle-Aged Individuals with Low Cardiovascular Disease Risk

Abstract

Aims: To investigate the microvascular function in apparently healthy individuals showing signs of early macrovascular endothelial dysfunction. Methods: Healthy participants aged between 30–55 years were recruited for the present study. Baseline measurements included body-mass index (BMI), waist-to-hip ratio (WHR), 24-h blood pressure, as well as fasted venous glucose, triglycerides (TG) and cholesterol (HDL, LDL and total). Brachial artery reactivity was measured using the flow-mediated dilation (FMD) technique and retinal vessel reactivity was assessed by using the Dynamic Retinal Vessel Analyser (DVA) in all individuals. The enrolled participants were separated in two groups, based on either a reduced (group 1:

Publication DOI: https://doi.org/10.3390/jcm11236962
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
Additional Information: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Uncontrolled Keywords: microvascular function,retina,vascular endothelial,flow-mediated dilation
Publication ISSN: 2077-0383
Last Modified: 24 Apr 2024 17:50
Date Deposited: 09 Dec 2022 16:10
Full Text Link:
Related URLs: https://www.mdp ... 0383/11/23/6962 (Publisher URL)
PURE Output Type: Article
Published Date: 2022-12
Published Online Date: 2022-11-25
Accepted Date: 2022-11-24
Submitted Date: 2022-11-03
Authors: Patel, Sunni
Shokr, Hala
Greenstein, Adam
Gherghel, Doina

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