Low-cost fabrication of PPIX liquid phantoms for use in fluorescence Measurements

Abstract

This article presents a liquid phantom technology that simulates the fluorescent properties of protoporphyrin IX (PPIX). A technology was developed for the isolation of PPIX from dark egg shells with a final concentration close to the real values in human tissues. A comparative analysis of the transmittance coefficient of the manufactured phantom as well as the fluorescence spectra measured through the combined use of a CCD spectrometer and a hyperspectral camera is presented as results.

Publication DOI: https://doi.org/10.1117/12.2626389
Divisions: College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
Funding Information: The authors acknowledge the support of the Russian Science Foundation under project No. 21-15-00325.
Additional Information: Copyright 2022 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. Funding Information: The authors acknowledge the support of the Russian Science Foundation under project No. 21-15-00325.
Uncontrolled Keywords: fluorescence imaging,fluorescence spectroscopy,optical phantom,protoporphyrin IX,Electronic, Optical and Magnetic Materials,Atomic and Molecular Physics, and Optics,Biomaterials,Radiology Nuclear Medicine and imaging
Publication ISSN: 1605-7422
Last Modified: 10 Apr 2024 07:21
Date Deposited: 29 Jun 2022 13:33
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2626389.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2022-04-29
Accepted Date: 2021-09-01
Authors: Shupletsov, Valery
Mikenkina, Margarita
Zherebtsov, Evgeny
Dremin, Viktor (ORCID Profile 0000-0001-6974-3505)
Bykov, Alexander
Potapova, Elena
Dunaev, Andrey
Meglinski, Igor (ORCID Profile 0000-0002-7613-8191)

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