Size and position of the optic disc crescent in a white European population with myopia

Abstract

Significance: One of the first clinically observed changes in the retina with progressing myopia is in the form of optic disc crescents. If such a change is predictive of myopia progression, it could aid in myopia management interventions to target those at greatest risk of progression and subsequent ocular morbidity. Purpose: To investigate the type, dimension and appearance of optic disc crescents and how they relate to the level of myopia. Methods: Retrospective data collection analysing retinal photographs of healthy children and adults with a refractive error of ≤−0.50 D sphere and astigmatism ≤2.00 D. Crescent location, maximum crescent width and vertical disc diameter were measured from retinal images of right eyes only. Results: Four-hundred eyes with a mean spherical error (SER) of −0.50 to −14.00 D (aged 7–81 years) were included (83.5% exhibited a discernible crescent). Mean (SD) maximum crescent width was 0.24 (0.24) mm. Univariate analysis showed a significant correlation between crescent width and age (r = 0.26, p < 0.001). SER was correlated with crescent width when controlling for age (r = −0.45, p < 0.001) and to the ratio of crescent width to vertical disc diameter (r = −0.43, p < 0.001). Temporal crescents were the most frequently observed (74%), followed by inferior temporal crescents (17%). One-way between-groups analysis of variance showed a significant difference between crescent locations (F = 5.2, p < 0.001). Post-hoc analysis revealed significant differences in SER between those with no crescent versus an inferior-temporal crescent, as well as differences between those with temporal versus inferior-temporal crescents. Other crescent locations did not differ significantly in the level of myopia. Participants not exhibiting a crescent had the lowest level of myopia (mean [SD] −3.03 [1.97)] D), while those with inferior temporal crescents had a mean (SD) SER of −5.01 (2.37) D. Conclusion: In this white European population, higher levels of SER were associated with increasing crescent size. Eyes with inferior temporally located crescents were more myopic.

Publication DOI: https://doi.org/10.1111/opo.13018
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Vision, Hearing and Language
College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG)
Additional Information: © 2022 The Authors. Ophthalmic and Physiological Optics published by John Wiley & Sons Ltd on behalf of College of Optometrists. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Funding Information: Open access funding enabled and organized by Projekt DEAL.
Uncontrolled Keywords: crescent,myopia,optic nerve head,peripapillary atrophy,Ophthalmology,Optometry,Sensory Systems
Publication ISSN: 1475-1313
Last Modified: 19 Jun 2024 16:45
Date Deposited: 20 Jun 2022 10:26
Full Text Link:
Related URLs: https://onlinel ... .1111/opo.13018 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2022-09
Published Online Date: 2022-06-20
Accepted Date: 2022-05-25
Authors: Hill, David
Heitmar, Rebekka
Logan, Nicola (ORCID Profile 0000-0002-0538-9516)

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