International multi-centre study of potential benefits of ultraviolet radiation protection using contact lenses

Abstract

Purpose To examine the effects of long-term ultraviolet radiation (UVR) blocking wearing contact lenses on ocular surface health, eye focus and macular pigment. Method 210 pre-presbyopic patients were recruited from Birmingham UK, Brisbane Australia, Hong Kong China, Houston USA and Waterloo Canada (n = 42 at each site). All patients had worn contact lenses for ≥ 5 years, half (test group) of a material incorporating a UVR-blocking filter. Ocular health was assessed using slit-lamp biomicroscopy and UV autofluorescence. Accommodation was measured subjectively with a push-up test and overcoming lens-induced defocus. Objective stimulus response and dynamic measures of the accommodative response were quantified with an open-field aberrometer. Macular pigment optical density (MPOD) was assessed using heterochromatic flicker photometry (MPS II). Results The two groups of participants were matched for age, sex, race, body-mass-index, diet, lifestyle, UVR exposure, refractive error and visual acuity. Limbal (p = 0.035), but not bulbar conjunctival redness (p = 0.903) was lower in eyes that had worn UVR-blocking contact lenses compared to controls. The subjective (8.0 ± 3.7D vs 7.3 ± 3.3D; p = 0.125) and objective (F = 1.255, p = 0.285) accommodative response was higher in the test group, but the differences did not reach significance. However, the accommodative latency was shorter in eyes that had worn UVR-blocking contact lenses (p = 0.003). There was no significant different in MPOD with UVR filtration (p = 0.869). Conclusions Blocking the transmission of UVR is beneficial in maintaining the eye’s ability to focus, suggesting that presbyopia maybe delayed in long-term UVR-blocking contact lenses wearers. These lenses also provide protection to the critical limbal region.

Publication DOI: https://doi.org/10.1016/j.clae.2022.101593
Divisions: College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG)
College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Optometry
Additional Information: © 2022 The Author(s). Published by Elsevier Ltd on behalf of British Contact Lens Association. This is an open access article under the CC BY license 4.0
Publication ISSN: 1476-5411
Full Text Link:
Related URLs: https://linking ... 367048422000315 (Publisher URL)
PURE Output Type: Article
Published Date: 2022-04-15
Published Online Date: 2022-04-15
Accepted Date: 2022-03-29
Authors: Wolffsohn, James S (ORCID Profile 0000-0003-4673-8927)
Dhallu, Sandeep
Aujla, Maana
Laughton, Debbie
Tempany, Keith
Powell, Daniel
Gifford, Kate
Gifford, Paul
Wan, Kin
Cho, Pauline
Stahl, Ulrike
Woods, Jill

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