Photoacoustic Imaging in Biomedicine and Life Sciences

Abstract

Photo-acoustic imaging, also known as opto-acoustic imaging, has become a widely popular modality for biomedical applications. This hybrid technique possesses the advantages of high optical contrast and high ultrasonic resolution. Due to the distinct optical absorption properties of tissue compartments and main chromophores, photo-acoustics is able to non-invasively observe structural and functional variations within biological tissues including oxygenation and deoxygenation, blood vessels and spatial melanin distribution. The detection of acoustic waves produced by a pulsed laser source yields a high scaling range, from organ level photo-acoustic tomography to sub-cellular or even molecular imaging. This review discusses significant novel technical solutions utilising photo-acoustics and their applications in the fields of biomedicine and life sciences.

Publication DOI: https://doi.org/10.3390/life12040588
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Additional Information: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
Uncontrolled Keywords: photo-acoustics,opto-acoustic imaging,biomedical imaging,photo-acoustic tomography,photo-acoustic microscopy,photo-acoustic endoscopy
Publication ISSN: 2075-1729
Full Text Link:
Related URLs: https://www.mdp ... 5-1729/12/4/588 (Publisher URL)
PURE Output Type: Review article
Published Date: 2022-04-14
Accepted Date: 2022-02-19
Authors: Neprokin, Alexey
Broadway, Christian
Myllylä, Teemu
Bykov, Alexander
Meglinski, Igor (ORCID Profile 0000-0002-7613-8191)

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