Clarke-Bland, Charlotte E., Bill, Roslyn M. and Devitt, Andrew (2022). Emerging roles for AQP in mammalian extracellular vesicles. BBA -Biomembranes, 1864 (3),
Abstract
Recent research in the aquaporin (AQP) field has identified a role for diverse AQPs in extracellular vesicles (EV). Though still in its infancy, there is a growing body of knowledge in the area; AQPs in EV have been suggested as biomarkers for disease, as drug targets and show potential as therapeutics. To advance further in this field, AQPs in EV must be better understood. Here we summarize current knowledge of the presence and function of AQPs in EV and hypothesise their roles in health and disease.
Publication DOI: | https://doi.org/10.1016/j.bbamem.2021.183826 |
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Divisions: | College of Health & Life Sciences College of Health & Life Sciences > School of Biosciences College of Health & Life Sciences > School of Biosciences > Cellular and Molecular Biomedicine College of Health & Life Sciences > Chronic and Communicable Conditions Aston University (General) |
Additional Information: | This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/4.0) Funding: We thank the Biotechnology and Biological Sciences Research Council for their support (through BB/P025927/1 to Roslyn Bill and BB/S00324X/1 to Andrew Devitt). |
Uncontrolled Keywords: | Aquaporin,Exosome,Extracellular vesicle,Inflammation,Microvesicle,Oedema,Signalling,Water channel,Biophysics,Biochemistry,Cell Biology |
Publication ISSN: | 1879-2642 |
Last Modified: | 02 Dec 2024 08:37 |
Date Deposited: | 13 Dec 2021 09:11 |
Full Text Link: |
https://linking ... 005273621002741 |
Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) |
PURE Output Type: | Article |
Published Date: | 2022-03-01 |
Published Online Date: | 2021-11-27 |
Accepted Date: | 2021-11-19 |
Authors: |
Clarke-Bland, Charlotte E.
(
0000-0001-5776-2733)
Bill, Roslyn M. ( 0000-0003-1331-0852) Devitt, Andrew ( 0000-0002-4651-6761) |