An Artificial Lens Capsule with a Lens Radial Stretching System Mimicking Dynamic Eye Focusing

Abstract

Presbyopia is a common eye disorder among aged people which is attributed to the loss of accommodation of the crystalline lens due to the increasing stiffness. One of the potential techniques to correct presbyopia involves removing the lens substance inside the capsule and replacing it with an artificial lens. The development of such devices, e.g., accommodating intraocular lenses (AIOLs), relies on the understanding of the biomechanical behaviour of the lens capsule and the essential design verification ex vivo. To mimic the eye’s dynamic focusing ability (accommodation), an artificial lens capsule (ALC), from silicone rubber accompanied by a lens radial stretching system (LRSS) was developed. The ALC was manufactured to offer a dimension and deforming behaviour replicating the human lens capsule. The LRSS was calibrated to provide a radial stretch simulating the change of diameter of capsules during accommodating process. The biomechanical function of the ALC was addressed by studying its evolution behaviour and reaction force under multiaxial stretch from the LRSS. The study highlighted the convenience of this application by performing preliminary tests on prototypes of ophthalmic devices (e.g., AIOLs) to restore accommodation.

Publication DOI: https://doi.org/10.3390/polym13203552
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG)
College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Vision, Hearing and Language
Additional Information: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). Funding: This research was funded by INNOVATE UK under the Knowledge Transfer Partnership between Aston University and Rayner Intraocular Lenses Limited, grant number 11718. L.D. was funded, in part, by a research grant (27616) from the College of Optometrists, UK
Uncontrolled Keywords: AIOL,ALC,Accommodation,LRSS,Presbyopia,Chemistry(all),Polymers and Plastics
Publication ISSN: 2073-4360
Last Modified: 30 Apr 2024 16:45
Date Deposited: 18 Oct 2021 10:34
Full Text Link:
Related URLs: https://www.mdp ... 4360/13/20/3552 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2021-10-15
Accepted Date: 2021-10-09
Authors: Wei, Huidong
Wolffsohn, James S. (ORCID Profile 0000-0003-4673-8927)
Gomes de Oliveria, Otavio
Davies, Leon N. (ORCID Profile 0000-0002-1554-0566)

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