Real-world studies support use of continuous glucose monitoring in Type 1 and Type 2 diabetes independently of treatment regimen


Numerous randomized controlled trials (RCTs) have demonstrated the glycemic benefits of continuous glucose monitoring (CGM) in management of type 1 diabetes (T1D) and type 2 diabetes. Although RCTs remain the gold standard clinical study design, findings from these trials do not necessarily reflect the effectiveness of CGM or reveal the feasibility and wider applications for use in broader real-life settings. This review evaluates recent real-world evidence (RWE) demonstrating the value of CGM to improve clinical outcomes, such as avoidance of severe hypoglycemic and hyperglycemic crises, and improved measures of psychological health and quality of life. Additionally, this review considers recent RWE for the role of CGM to enhance health care resource utilization, including prediction of T1D and applications in gestational diabetes, chronic kidney disease, and monitoring during surgery.

Publication DOI:
Divisions: College of Health & Life Sciences > School of Biosciences
College of Health & Life Sciences
Additional Information: © James R. Gavin, III and Clifford J. Bailey, 2021; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. Funding Information: Funding for the development of the manuscript was provided by Abbott Diabetes Care.
Uncontrolled Keywords: CGM,Hospitalizations,Observational,RCTs,Type 1 diabetes,Type 2 diabetes,Endocrinology, Diabetes and Metabolism,Endocrinology,Medical Laboratory Technology
Publication ISSN: 1557-8593
Last Modified: 18 Jun 2024 07:55
Date Deposited: 04 Oct 2021 07:48
Full Text Link:
Related URLs: https://www.lie ... 9/dia.2021.0211 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2021-09
Published Online Date: 2021-06-24
Accepted Date: 2021-06-24
Authors: Gavin, James R.
Bailey, Clifford (ORCID Profile 0000-0002-6998-6811)



Version: Published Version

License: Creative Commons Attribution

| Preview

Export / Share Citation


Additional statistics for this record