Characterization and modelling the mechanical behaviour of poly (l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding


Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.

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Divisions: College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences
Additional Information: Copyright The Author(s) 2019. Open Access - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Funding: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 691238 involving Italian National Agency for New Technologies, Energy and Sustainable Economic Development (Italy), University of Warwick (UK), Queen’s University Belfast (UK) and California Institute of Technology (US).
Uncontrolled Keywords: Mechanical behaviour,Constitutive model,Stretch blow moulding,Glass transition,PLLA
Publication ISSN: 1960-6214
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Related URLs: https://link.sp ... 289-018-01463-2 (Publisher URL)
PURE Output Type: Article
Published Date: 2020-01-01
Published Online Date: 2019-01-10
Accepted Date: 2018-12-03
Authors: Wei, Huidong
Yan, Shiyong
Geol, Saurav
Menary, Gary



Version: Published Version

License: Creative Commons Attribution

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