Audit of vaccination status of health-care workers who tested positive for SARS-CoV-2


Multiple SARS-CoV-2 vaccinations have shown excellent efficacy during clinical trials. However, post vaccine surveillance is important to confirm ‘real-world’ findings of vaccine efficacy and safety. It is therefore imperative to identify individuals that become infected with SARS-CoV-2 post vaccination. We investigated the vaccination status of staff that had tested positive in a cohort of healthcare workers in one large tertiary hospital in the UK. At the time of the investigation, 8th December 2020 to 13th March 2021, 11,871 staff had been vaccinated and 225 staff tested positive for SARS-CoV-2. This period coincided with the second wave of SARS-CoV-2 infections in the UK which was driven by the Alpha variant. No healthcare workers who were double vaccinated had a positive PCR test for SARS-CoV-2 during this study period confirming vaccination with Pfizer BioNTec BNT162b2 gives excellent protection against infection of this variant.

Publication DOI:
Divisions: College of Health & Life Sciences > Aston Medical School
Additional Information: © 2021 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (
Publication ISSN: 2667-0380
Last Modified: 20 Mar 2024 08:15
Date Deposited: 03 Sep 2021 08:15
Full Text Link:
Related URLs: https://linking ... 667038021000326 (Publisher URL)
PURE Output Type: Article
Published Date: 2021-12
Published Online Date: 2021-09-02
Accepted Date: 2021-08-24
Authors: Berry, L.
Jones, K
Robbins, T.
Anderson, N.
Morgan, N.
Patel, K.
Hardy, Andrew
Kyrou, I. (ORCID Profile 0000-0002-6997-3439)
Randeva, H.

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