Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

Abstract

Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.

Publication DOI: https://doi.org/10.1117/12.2523190
Divisions: College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
Funding Information: The research was supported by the grant of the RFBR-r_a (project 17-41-590560) in respect of the design and assembling of the experimental setup; by the grant of the President of the Russian Federation for state support of young Russian scientists № MK-34
Additional Information: Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Cold pressor test,Laser Doppler flowmetry,Microcirculation,Rheumatic diseases,Velocity of capillary blood flow,Videocapillaroscopy,Electronic, Optical and Magnetic Materials,Biomaterials,Atomic and Molecular Physics, and Optics,Radiology Nuclear Medicine and imaging
Publication ISSN: 1996-756X
Last Modified: 12 Dec 2024 08:25
Date Deposited: 18 Dec 2020 15:45
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2523190.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2019-06-03
Accepted Date: 2018-09-01
Authors: Stavtsev, Dmitry D.
Volkov, Mikhail V.
Margaryants, Nikita B.
Potemkin, Andrey V.
Dremin, Viktor V. (ORCID Profile 0000-0001-6974-3505)
Kozlov, Igor O.
Makovik, Irina N.
Zherebtsov, Evgeny A.
Dunaev, Andrey V.

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