Analysis of changes in blood flow oscillations under different probe pressure using laser Doppler spectrum decomposition

Abstract

Presently, in the modern laser Doppler flowmetry (LDF) the distribution of blood perfusion and its changes along the Doppler shift frequencies are simply ignored and/or not properly addressed. Utilizing the registered power spectrum of photocurrent, we introduce an LDF signal processing approach suitable for expanding of diagnostic capabilities of the technique. In particular, we demonstrate that it is possible to determine how the oscillations of blood flow (cardiac, breathe, myogenic, etc.) are distributed along the Doppler shift frequency. Wavelet analysis is utilized to extract the oscillations corresponded to the particular frequency sub-bands of blood perfusion. The main purpose of this study is to identify influence of local pressure by fiber optic probe on cardiac oscillations and their distribution along frequency of Doppler shift.

Publication DOI: https://doi.org/10.1117/12.2527040
Divisions: College of Engineering & Physical Sciences
College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
Additional Information: Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Blood flow oscillations,Blood perfusion,Laser Doppler flowmetry,Probe pressure effects,Spectrum decomposition,Electronic, Optical and Magnetic Materials,Mechanics of Materials
Publication ISSN: 1996-756X
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Conference article
Published Date: 2019-07-22
Accepted Date: 2019-06-01
Authors: Kozlov, Igor O.
Zherebtsov, Evgeny A. (ORCID Profile 0000-0002-3635-1430)
Mezentsev, Mikhail A.
Shupletsov, Valery V.
Potapova, Elena V.
Zherebtsova, Angelina I.
Dremin, Viktor V. (ORCID Profile 0000-0001-6974-3505)
Dunaev, Andrey V.
Meglinski, Igor V. (ORCID Profile 0000-0002-7613-8191)

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