Imaging of early stage breast cancer with circularly polarized light

Abstract

In this study, we utilize the properties of polarized light for the analysis of paraffin-embedded breast cancer samples. We perform the measurements of the full Stokes vector of back-reflected radiation and calculate the degree of polarization as a diagnostic criterion for the separation of healthy and cancer sample sections. We show that circularly polarized light scattered within the breast sample is sensitive to the presence of cancer cells. The degree of the polarization of the reected light was found to be the most sensitive parameter for the reliable differentiation of tissue.

Publication DOI: https://doi.org/10.1117/12.2554166
Divisions: College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
Additional Information: Copyright 2020 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Breast cancer,Degree of polarization,Polarimetric imaging,Stokes polarimetry,Electronic, Optical and Magnetic Materials,Condensed Matter Physics,Computer Science Applications,Applied Mathematics,Electrical and Electronic Engineering
Publication ISSN: 1996-756X
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2554166.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2020-04-07
Accepted Date: 2020-04-01
Authors: Dremin, Viktor (ORCID Profile 0000-0001-6974-3505)
Anin, Dmytro
Sieryi, Oleksii
Borovkova, Mariia
Näpänkangas, Juha
Meglinski, Igor (ORCID Profile 0000-0002-7613-8191)
Bykov, Alexander

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