Dremin, Viktor, Anin, Dmytro, Sieryi, Oleksii, Borovkova, Mariia, Näpänkangas, Juha, Meglinski, Igor and Bykov, Alexander (2020). Imaging of early stage breast cancer with circularly polarized light. Proceedings of SPIE - The International Society for Optical Engineering, 11363 ,
Abstract
In this study, we utilize the properties of polarized light for the analysis of paraffin-embedded breast cancer samples. We perform the measurements of the full Stokes vector of back-reflected radiation and calculate the degree of polarization as a diagnostic criterion for the separation of healthy and cancer sample sections. We show that circularly polarized light scattered within the breast sample is sensitive to the presence of cancer cells. The degree of the polarization of the reected light was found to be the most sensitive parameter for the reliable differentiation of tissue.
| Publication DOI: | https://doi.org/10.1117/12.2554166 |
|---|---|
| Divisions: | College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT) College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design |
| Funding Information: | Authors acknowledge the support of the Academy of Finland (grants: 314369 and 325097), the ATTRACT project funded by the EU under Grant Agreement 777222. This study was also supported by the Russian Science Foundation under projects No. 19-79-00082 (exper |
| Additional Information: | Copyright 2020 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. |
| Uncontrolled Keywords: | Breast cancer,Degree of polarization,Polarimetric imaging,Stokes polarimetry,Electronic, Optical and Magnetic Materials,Condensed Matter Physics,Computer Science Applications,Applied Mathematics,Electrical and Electronic Engineering |
| Publication ISSN: | 1996-756X |
| Last Modified: | 16 Apr 2024 07:24 |
| Date Deposited: | 16 Dec 2020 16:37 |
| Full Text Link: | |
| Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) https://www.spi ... 12.2554166.full (Publisher URL) |
PURE Output Type: | Conference article |
| Published Date: | 2020-04-07 |
| Accepted Date: | 2020-04-01 |
| Authors: |
Dremin, Viktor
(
0000-0001-6974-3505)
Anin, Dmytro Sieryi, Oleksii Borovkova, Mariia Näpänkangas, Juha Meglinski, Igor (
0000-0002-7613-8191)
Bykov, Alexander |
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)