Masked comparison of two silicone hydrogel bandage contact lenses after photorefractive keratectomy


Purpose: To compare the efficiency and safety of two bandage contact lenses after photorefractive keratectomy (PRK). Methods: In this double-blind study, 45 patients (90 eyes) received PRK in both eyes and wore bandage contact lenses (BCLs), PureVision (Bausch & Lomb, Rochester, NY, USA) in one eye and PureVision2 (Bausch & Lomb, Rochester, NY, USA) in the other eye, randomly assigned. The medication regimen after surgery was the same for both eyes. The epithelial defect's size, conjunctival hyperemia and lens centration were graded objectively using slit-lamp biomicroscopy on days 1, 3 and 5 after surgery. Also ocular symptoms of discomfort including tearing, photophobia, foreign body sensation and visual fluctuations were assessed subjectively at each visit. Results: The mean epithelial defect size on the first day after operation was similar in eyes fitted with PureVision (30.08 ± 5.30 mm²) and PureVision2 (30.25 ± 5.72 mm2) lenses. (p = 0.79) Contact lens deposits and bulbar hyperaemia on days 1 and 3 after PRK were similar between the two eyes, but were significantly greater on day 5 for PureVision2 lenses. (p = 0.02; p = 0.04 respectively) There was no difference in contact lens decentration, and discomfort symptoms including pain, tearing, foreign body sensation, photophobia and visual fluctuations between the eyes fitted with PureVision and PureVision2. (p > 0.05) Conclusions: PureVision and PureVision2 contact lenses are equivalent as bandage lenses in important aspects such as corneal re-epithelialization and subjective comfort., although PureVision2 led to a higher incidence of contact lens deposits and conjunctival hyperemia early post-PRK.

Publication DOI:
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
Funding Information: The authors would like to thank the participants who made this study possible and the Deputy of Research of Mashhad University of Medical Sciences. (Ethic code: 940094).
Additional Information: © 2020, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Uncontrolled Keywords: Balafilcon A,Bandage contact lens,Photorefractive keratectomy PRK,Silicone hydrogel,Ophthalmology,Optometry
Publication ISSN: 1476-5411
Last Modified: 08 Jul 2024 07:58
Date Deposited: 12 Mar 2020 13:29
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.sci ... 367048420300230 (Publisher URL)
PURE Output Type: Article
Published Date: 2020-06
Published Online Date: 2020-02-23
Accepted Date: 2020-02-12
Authors: Bagherian, Homa
Zarei-Ghanavati, Siamak
Momeni-Moghaddam, Hamed
Wolffsohn, James S. (ORCID Profile 0000-0003-4673-8927)
Sedaghat, Mohammad Reza
Naroo, Shehzad A. (ORCID Profile 0000-0002-6373-7187)
Monfared, Naeemeh

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