Influence of blood pulsation on diagnostic volume in pulse oximetry and photoplethysmography measurements


Recent advances in the development of ultra-compact semiconductor lasers and technology of printed flexible hybrid electronics have opened broad perspectives for the design of new pulse oximetry and photoplethysmography devices. Conceptual design of optical diagnostic devices requires careful selection of various technical parameters, including spectral range; polarization and intensity of incident light; actual size, geometry, and sensitivity of the detector; and mutual position of the source and detector on the surface of skin. In the current study utilizing a unified Monte Carlo computational tool, we explore the variations in diagnostic volume due to arterial blood pulsation for typical transmitted and back-scattered probing configurations in a human finger. The results of computational studies show that the variations in diagnostic volumes due to arterial pulse wave are notably (up to 45%) different in visible and near-infrared spectral ranges in both transmitted and back-scattered probing geometries. While these variations are acceptable for relative measurements in pulse oximetry and/or photoplethysmography, for absolute measurements, an alignment normalization of diagnostic volume is required and can be done by a computational approach utilized in the framework of the current study.

Publication DOI:
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Funding Information: Funding. Academy of Finland (290596, 314369, 318281); Russian Science Foundation (19-79-00082); Russian Foundation for Basic Research (18-02-00669); MEPhI Academic Excellence Project (02.a03.21.0005); National Research Tomsk State University Academic D.I.
Additional Information: © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. Authors and readers may use, reuse, and build upon the article, or use it for text or data mining without asking prior permission from the publisher or the Author(s), as long as the purpose is non-commercial and appropriate attribution is maintained. Funding: EP/R024898/1
Uncontrolled Keywords: Atomic and Molecular Physics, and Optics,Engineering (miscellaneous),Electrical and Electronic Engineering
Publication ISSN: 2155-3165
Last Modified: 18 Mar 2024 08:34
Date Deposited: 16 Dec 2019 08:56
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.osa ... i=ao-58-34-9398 (Publisher URL)
PURE Output Type: Article
Published Date: 2019-11-22
Published Online Date: 2019-10-25
Accepted Date: 2019-10-25
Authors: Dremin, Viktor
Zherebtsov, Evgeny
Bykov, Alexander
Popov, Alexey
Doronin, Alexander
Meglinski, Igor (ORCID Profile 0000-0002-7613-8191)



Version: Published Version

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