Royston, R, Oliver, C, Howlin, P, Dosse, A, Armitage, P, Moss, J and Waite, J (2020). The Profiles and Correlates of Psychopathology in Adolescents and Adults with Williams, Fragile X and Prader-Willi Syndromes. Journal of Autism and Developmental Disorders, 50 (3), pp. 893-903.
Abstract
Psychopathology is prevalent in Williams (WS), fragile X (FXS) and Prader-Willi (PWS) syndromes. However, little is known about the potential correlates of psychopathology in these groups. A questionnaire study was completed by 111 caregivers of individuals with WS (n = 35); FXS (n = 50) and PWS (n = 26). Mean age was 26 years (range 12-57 years); 74 (67%) were male. Multiple regression analyses indicated that higher rates of health problems and sensory impairments predicted higher psychopathology in WS (p < .0001). In PWS, poorer adaptive ability predicted higher overall psychiatric disturbance (p = .001), generalised anxiety (p = .006) and hyperactivity (p = .003). There were no significant predictors in FXS. This study highlights dissociations in the potential risk markers of psychopathology between genetic syndromes. Implications for intervention are discussed.
| Publication DOI: | https://doi.org/10.1007/s10803-019-04317-1 |
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| Divisions: | College of Health & Life Sciences > School of Psychology Aston University (General) |
| Additional Information: | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| Uncontrolled Keywords: | Correlates,Fragile X syndrome,Prader–Willi syndrome,Psychopathology,Williams syndrome,Developmental and Educational Psychology |
| Publication ISSN: | 1573-3432 |
| Last Modified: | 11 Nov 2024 08:27 |
| Date Deposited: | 12 Dec 2019 12:52 |
| Full Text Link: | |
| Related URLs: |
https://link.sp ... 803-019-04317-1
(Publisher URL) http://www.scop ... tnerID=8YFLogxK (Scopus URL) |
PURE Output Type: | Article |
| Published Date: | 2020-03-01 |
| Published Online Date: | 2019-12-04 |
| Accepted Date: | 2019-12-01 |
| Authors: |
Royston, R
Oliver, C Howlin, P Dosse, A Armitage, P Moss, J Waite, J ( 
0000-0002-8676-3070)
|
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)