A Cross-sectional Examination of the Clinical Significance of Autistic Traits in Individuals Experiencing a First Episode of Psychosis


Autism traits are found at elevated rates in individuals with schizophrenia spectrum disorders, however, there is a lack of evidence regarding potential clinical impact. The current research aimed to examine potential associations between autism traits and symptoms of psychosis, social and role functioning, and quality of life. 99 individuals experiencing a first episode of psychosis took part in a cross-sectional interview and self-report questionnaire which assessed current symptoms of psychosis, autism traits, functioning, and quality of life. Participants were found to have a high level of autism traits. Higher autism traits were associated with poorer quality of life, functioning, and current psychotic symptoms. Receiver operating characteristic curve (ROC) analyses indicated that optimal AQ cut-off scores to predict severity of psychosis symptoms, functioning, and quality of life were lower than those used to suggest likely autism-spectrum diagnosis. Results suggest that autism traits are associated with poorer clinical presentation in first-episode psychosis populations, even in those whose traits fall below potentially diagnostic thresholds for autism. Psychosis services should be prepared to adequately address the needs of individuals with higher autism traits.

Publication DOI: https://doi.org/10.1016/j.psychres.2019.112623
Divisions: College of Health & Life Sciences > School of Psychology
College of Health & Life Sciences
Additional Information: © 2019, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Uncontrolled Keywords: Autism traits,Functioning,Quality of life,Schizophrenia spectrum disorders,Psychiatry and Mental health,Biological Psychiatry
Publication ISSN: 0165-1781
Last Modified: 12 Jun 2024 07:18
Date Deposited: 12 Nov 2019 16:11
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Related URLs: https://www.sci ... 165178119309977 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2019-12-01
Published Online Date: 2019-10-18
Accepted Date: 2019-10-18
Authors: Chisholm, Katharine (ORCID Profile 0000-0002-0575-0789)
Pelton, Mirabel
Duncan, Nikita
Kidd, Katharine
Wardenaar, Klaas
Upthegrove, Rachel
Broome, Matthew
Lin, Ashleigh
Wood, Stephen

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